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Protein Overview: CG7280-PA

General Information:
Name(s) found: CG7280-PA / FBpp0074426 [FlyBase]
Description(s) found:
Found 22 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG7280 (CG7280, FBgn0030966). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:18740415..18742584. It has the cytological map location 17E1. Based on sequence similarity, it is predicted to have molecular function</span>: sulfite oxidase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: sulfur metabolic process. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 573 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial intermembrane space [ISS][NAS]
    Biological Process: sulfur metabolic process [ISS]
    protein catabolic process [NAS]
    oxidation reduction [IEA]
    Molecular Function: electron carrier activity [IEA]
    sulfite oxidase activity [ISS][NAS]
    molybdenum ion binding [IEA]
    heme binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRLLRPSWAG LLRGRHHQHQ RHHRRLLLTT SRGSNGEREE QQHSQWSSPG SRSEQLFYAA  60
   61 FWAGGLTLGY HWLTDKKNHV LLEGQKVASE EELEATARLW HVTNRRELPT YRAEEVEQHN 120
  121 SVEKRIWVTY GLGVYDVTDF VENHPGGDKI LMAAGSAIDP FWGIYQQHNT LEVLELLEGF 180
  181 RIGNLEGLVV TNVDDELGSP WSQEPQRHAL LKPASKRPFN AEPPIGLLAE QFYTPNELFY 240
  241 VRNHLPVPVI NPEDYELEIE GGAKDKTLTL DGIKALPKHS VTAAIMCGGN RRSEMTKVKA 300
  301 VKGLSWGAGA VGNAKWSGAR LCDILREQGV QPDETKHVIF EGADLDPTSH PYGASIPLAK 360
  361 ALDPRGDVIL AYEMNDEPLS RDHGFPIRVI VPGTVGARNV KWLTRIVVAD KESDSHWQQN 420
  421 DYKGFSPSTD WDTVDFSKSD AIQAMPVTSA ICTPQPGARV KVDDDEGHIT VRGYAWSGGG 480
  481 RKIVRVDLTN DEGVSWHVAE LEQEEMPDGR HYGWSLWTAR LPVSEAQRRA GDVEIWAKAV 540
  541 DSAYNVQPEK FEHIWNLRGV LANAYHKVKV KII

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..101] MSA 4.151996 View MSA. No confident structure predictions are available.
    2 View Details [102..573] PSI-BLAST 98.045757 Sulfite oxidase, C-terminal domain; Sulfite oxidase, N-terminal domain; Sulfite oxidase, middle catalytic domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • sulfite oxidase activity
    		•  3.51337503004627 bayes_pls_golite062009
  • oxidoreductase activity, acting on sulfur group of donors, oxygen as acceptor
    		•  1.96064934018532 bayes_pls_golite062009
  • binding
    		•  1.13937274704645 bayes_pls_golite062009
  • molybdopterin cofactor binding
    		•  0.928574039561971 bayes_pls_golite062009
  • oxidoreductase activity, acting on sulfur group of donors
    		•  0.39125796343404 bayes_pls_golite062009
  • protein binding
    		•  0.268795825133297 bayes_pls_golite062009
  • ligand-gated ion channel activity
    		•  0.203350317729126 bayes_pls_golite062009
  • ligand-gated channel activity
    		•  0.203350317729126 bayes_pls_golite062009
  • hydrolase activity
    		•  0.157008651395982 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.61

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle