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Protein Overview: Arpc3B-PA

General Information:
Name(s) found: Arpc3B-PA / FBpp0074184 [FlyBase]
Description(s) found:
Found 23 descriptions.
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  • The gene Arpc3B is referred to in FlyBase by the symbol Dmel\Arpc3B (CG8936, FBgn0065032). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:16998604..16999885. It has the cytological map location 15E3. Based on sequence similarity, it is predicted to have molecular function</span>: actin binding. It is reported to be involved in the biological process</span>: actin filament organization. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 174 amino acids

    Gene Ontology:
    Cellular Component: germline ring canal [IDA]
    cytoskeleton [IEA]
    Arp2/3 protein complex [NAS]
    Biological Process: regulation of actin filament polymerization [IEA]
    actin filament organization [NAS]
    Molecular Function: actin binding [ISS]
    structural constituent of cytoskeleton [NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPAFHSEIED FQASVGNMAL LPLRTQVRGP APTVDIPNDI IDESLYFWKS NIFFRTYEVK  60
   61 SEVDRVLIYI TLYITECLKR LARCTSKSQG QQELYTLAIS RFDIPGDAGF PLNGIYTKPE 120
  121 DPELMRQYFL QLRQETGNRL LEKVFDTPDG KPSKWWICFA KKKFMEKSLS GPGM

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..174] PSI-BLAST 91.522879 Arp2/3 complex 21 kDa subunit ARPC3

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • actin binding
    		•  5.63989846641024 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  4.21664682046338 bayes_pls_golite062009
  • actin filament binding
    		•  3.53574857524507 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  2.90019731783322 bayes_pls_golite062009
  • binding
    		•  1.94576284584165 bayes_pls_golite062009
  • protein binding
    		•  0.756249220099259 bayes_pls_golite062009
  • structural molecule activity
    		•  0.662672430262145 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle