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Protein Overview: TH1-PA, FBpp0309276

General Information:
Name(s) found: FBpp0309276 [FlyBase]
TH1-PA / FBpp0074080 [FlyBase]
Description(s) found:
Found 32 descriptions.
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  • type=protein; loc=X:complement(16283329..16283360,16283429..16283910,16283979..16284425,16284496..16285208,16285325..16285387); ID=FBpp0309276; name=TH1-PB; parent=FBgn0010416,FBtr0340315; dbxref=FlyBase:FBpp0309276,FlyBase_Annotation_IDs:CG9984-PB; MD5=90a19c8f6e99eebaffaa616831e6ad23; length=578; release=r5.56; species=Dmel; [FlyBase]
  • The gene TH1 is referred to in FlyBase by the symbol Dmel\TH1 (CG9984, FBgn0010416). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:16282853..16285443. It has the cytological map location 14C2-14C3. There is experimental evidence that it has the molecular function</span>: mRNA binding. There is experimental evidence that it is involved in the biological process</span>: negative regulation of transcription from RNA polymerase II promoter, mitotic. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 578 amino acids

    Gene Ontology:
    Cellular Component: transcriptional repressor complex [IDA]
    Biological Process: negative regulation of transcription from RNA polymerase II promoter, mitotic [IDA]
    negative regulation of transcription [IEA]
    Molecular Function: mRNA binding [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEVEYDDSGW QGRAKGQTNP EETLEDNPQK TIQECLEKFL TPDYIMEPGI FTQLKRYFQS  60
   61 GGSPEEVISM LSENYKAVAQ MANLLAEWLI LAGVKVTEVQ AMVENHLKEM ILKSFDPKKA 120
  121 DTIFTEEGET PDWLTEMIDH YTWRSLIYRL AEEYPDCLML NFTIKLISDA GFQSEITSIS 180
  181 TAAQQIEVFS RVLKTSIVKF LNNPDDVHGA IQECARMVCH GQHTYVYSQV LIQVLSQEQK 240
  241 GGFNMKRLSQ EIIKYALQNN QNVTPITMAL NGSAVYPQAC QALTSMLTRN TLNPADITVL 300
  301 FRNYSGSDPP PIDLIRNPQF LELLVDALFR SGVKINPEHK PKYMFLLAYA SAVIDQPAKK 360
  361 RPMTERMLNK EELKSTIQAI EKAHTICNVD QGSTELIAEL QTLYNCIKYP VVGVGVIRWI 420
  421 ENVVMEPSYF KLSTDSCPTH LAVLDEVAAV HPTLQQQILF LLIRLFESKQ DELEILVQLE 480
  481 MKKMILDRMV NLLTRGCVVP VLRYIKQCCA IEDTDISLIR YFVTEVLETI THPYSPEFVQ 540
  541 LFLPMVENEE ITGTMRGEGD NDPVSEFIVH CKAHYTTV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..166] MSA 1.016918 View MSA. No confident structure predictions are available.
    2 View Details [167..309] deduced N/A No confident structure predictions are available.
    3 View Details [310..359] MSA 1.018986 View MSA. No confident structure predictions are available.
    4 View Details [360..578] MSA 1.020973 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

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