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Protein Overview: Dsp1-PA, Dsp1-PB...

General Information:
Name(s) found: Dsp1-PC / FBpp0088320 [FlyBase]
Dsp1-PA / FBpp0088319 [FlyBase]
Dsp1-PB / FBpp0088318 [FlyBase]
Description(s) found:
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  • gi|24642476|ref|NP_542446.2| dorsal switch protein 1, isoform C [Drosophila melanogaster] [NCBI NR]
  • gi|24642474|ref|NP_727961.1| dorsal switch protein 1, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|24642472|ref|NP_727960.1| dorsal switch protein 1, isoform A [Drosophila melanogaster] [NCBI NR]
  • gi|22832358|gb|AAF48594.2| dorsal switch protein 1, isoform C [Drosophila melanogaster] [NCBI NR]
  • gi|22832357|gb|AAN09396.1| dorsal switch protein 1, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|22832356|gb|AAN09395.1| dorsal switch protein 1, isoform A [Drosophila melanogaster] [NCBI NR]
  • gi|16768340|gb|AAL28389.1| GM02110p [Drosophila melanogaster] [NCBI NR]
  • The gene Dorsal switch protein 1 is referred to in FlyBase by the symbol Dmel\Dsp1 (CG12223, FBgn0011764). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:16227645..16232927. It has the cytological map location 14B14-14B15. It is reported to have molecular function</span>: single-stranded DNA binding; transcription corepressor activity. There is experimental evidence that it is involved in the biological process</span>: negative regulation of antimicrobial humoral response; leg disc development. 11 alleles are reported. The phenotypes of these alleles are annotated with 14 unique terms, many of which group under: adult segment; organ system; peripheral nervous system; abdominal ventral denticle belt; thoracic segment; nervous system; adult mesothoracic segment; integumentary plate; cuticle; adult abdominal segment; egg; abdominal 5 ventral denticle belt; multi-cell-component structure; external compound sense organ. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase]
  • >CG12223-PB translation from_gene[CG12223 Dsp1 FBgn0011764] seq_release:3 mol_weight=43908 cds_boundaries:(X:16,065,409..16,068,823[+]) aa_length:385 transcript_info:[CG12223-RB seq_release:3] gene_info:[gene symbol:Dsp1 FLAGGED_PROBLEMATIC FBgn0011764 [hmr_yeast5_DM3-1_pombe.fasta]
  • >CG12223-PA translation from_gene[CG12223 Dsp1 FBgn0011764] seq_release:3 mol_weight=43908 cds_boundaries:(X:16,065,409..16,068,823[+]) aa_length:385 transcript_info:[CG12223-RA seq_release:3] gene_info:[gene symbol:Dsp1 FLAGGED_PROBLEMATIC FBgn0011764 [hmr_yeast5_DM3-1_pombe.fasta]
  • >CG12223-PC translation from_gene[CG12223 Dsp1 FBgn0011764] seq_release:3 mol_weight=43908 cds_boundaries:(X:16,065,409..16,068,823[+]) aa_length:385 transcript_info:[CG12223-RC seq_release:3] gene_info:[gene symbol:Dsp1 FLAGGED_PROBLEMATIC FBgn0011764 [hmr_yeast5_DM3-1_pombe.fasta]
  • CG12223-PC, isoform C [Drosophila melanogaster]gi|22832357|gb|AAN09396.1| CG12223-PB, isoform B [Drosophila melanogaster]gi|22832356|gb|AAN09395.1| CG12223-PA, isoform A [Drosophila melanogaster]gi|16768340|gb|AAL28389.1| GM02110p [Drosophila melanogas [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=X:join(16228423..16228446,16230324..16230776,16230884..16231042,16231119..16231282,16231414..16231588,16231658..16231840); ID=FBpp0088318; name=Dsp1-PB; parent=FBgn0011764,FBtr0089259; dbxref=FlyBase:FBpp0088318,FlyBase_Annotation_IDs:CG [fly-100309-contam.fasta]
  • type=protein; loc=X:join(16228423..16228446,16230324..16230776,16230884..16231042,16231119..16231282,16231414..16231588,16231658..16231840); ID=FBpp0088319; name=Dsp1-PA; parent=FBgn0011764,FBtr0089260; dbxref=FlyBase:FBpp0088319,FlyBase_Annotation_IDs:CG [fly-100309-contam.fasta]
  • type=protein; loc=X:join(16228423..16228446,16230324..16230776,16230884..16231042,16231119..16231282,16231414..16231588,16231658..16231840); ID=FBpp0088320; name=Dsp1-PC; parent=FBgn0011764,FBtr0089261; dbxref=FlyBase:FBpp0088320,FlyBase_Annotation_IDs:CG [fly-100309-contam.fasta]
  • CG12223-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Dorsal switch protein 1 CG12223-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG12223-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • GM02110p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG12223-PC, isoform C [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Dorsal switch protein 1 CG12223-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Dorsal switch protein 1 CG12223-PC, isoform C [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=X:join(16228423..16228446,16230324..16230776,16230884..16231042,16231119..16231282,16231414..16231588,16231658..16231840); ID=FBpp0088318; name=Dsp1-PB; parent=FBgn0011764,FBtr0089259; dbxref=FlyBase:FBpp0088318,FlyBase_Annotation_IDs:CG12223-PB,GB_protein:AAN09396.1,REFSEQ:NP_727961,GB_protein:AAN09396; MD5=891c61eae6e1a822323843f98b2ed71e; length=385; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=X:join(16228423..16228446,16230324..16230776,16230884..16231042,16231119..16231282,16231414..16231588,16231658..16231840); ID=FBpp0088319; name=Dsp1-PA; parent=FBgn0011764,FBtr0089260; dbxref=FlyBase:FBpp0088319,FlyBase_Annotation_IDs:CG12223-PA,GB_protein:AAN09395.1,REFSEQ:NP_727960,GB_protein:AAN09395; MD5=891c61eae6e1a822323843f98b2ed71e; length=385; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=X:join(16228423..16228446,16230324..16230776,16230884..16231042,16231119..16231282,16231414..16231588,16231658..16231840); ID=FBpp0088320; name=Dsp1-PC; parent=FBgn0011764,FBtr0089261; dbxref=FlyBase:FBpp0088320,FlyBase_Annotation_IDs:CG12223-PC,GB_protein:AAF48594.2,REFSEQ:NP_542446,GB_protein:AAF48594; MD5=891c61eae6e1a822323843f98b2ed71e; length=385; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=X:join(16228423..16228446,16230324..16230776,16230884..16231042,16231119..16231282,16231414..16231588,16231658..16231840); ID=FBpp0088318; name=Dsp1-PB; parent=FBgn0011764,FBtr0089259; dbxref=FlyBase:FBpp0088318,FlyBase_Annotation_IDs:CG12223-PB,GB_protein:AAN09396.1,REFSEQ:NP_727961,GB_protein:AAN09396; MD5=891c61eae6e1a822323843f98b2ed71e; length=385; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • type=protein; loc=X:join(16228423..16228446,16230324..16230776,16230884..16231042,16231119..16231282,16231414..16231588,16231658..16231840); ID=FBpp0088319; name=Dsp1-PA; parent=FBgn0011764,FBtr0089260; dbxref=FlyBase:FBpp0088319,FlyBase_Annotation_IDs:CG12223-PA,GB_protein:AAN09395.1,REFSEQ:NP_727960,GB_protein:AAN09395; MD5=891c61eae6e1a822323843f98b2ed71e; length=385; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • type=protein; loc=X:join(16228423..16228446,16230324..16230776,16230884..16231042,16231119..16231282,16231414..16231588,16231658..16231840); ID=FBpp0088320; name=Dsp1-PC; parent=FBgn0011764,FBtr0089261; dbxref=FlyBase:FBpp0088320,FlyBase_Annotation_IDs:CG12223-PC,GB_protein:AAF48594.2,REFSEQ:NP_542446,GB_protein:AAF48594; MD5=891c61eae6e1a822323843f98b2ed71e; length=385; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • Isoform A of High mobility group protein DSP1 OS=Drosophila melanogaster GN=Dsp1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=X:join(16228423..16228446,16230324..16230776,16230884..16231042,16231119..16231282,16231414..16231588,16231658..16231840); ID=FBpp0088318; name=Dsp1-PB; parent=FBgn0011764,FBtr0089259; dbxref=FlyBase:FBpp0088318,FlyBase_Annotation_IDs:CG12223-PB,GB_protein:AAN09396.1,REFSEQ:NP_727961,GB_protein:AAN09396; MD5=891c61eae6e1a822323843f98b2ed71e; length=385; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=X:join(16228423..16228446,16230324..16230776,16230884..16231042,16231119..16231282,16231414..16231588,16231658..16231840); ID=FBpp0088319; name=Dsp1-PA; parent=FBgn0011764,FBtr0089260; dbxref=FlyBase:FBpp0088319,FlyBase_Annotation_IDs:CG12223-PA,GB_protein:AAN09395.1,REFSEQ:NP_727960,GB_protein:AAN09395,FlyMine:FBpp0088319,modMine:FBpp0088319; MD5=891c61eae6e1a822323843f98b2ed71e; length=385; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=X:join(16228423..16228446,16230324..16230776,16230884..16231042,16231119..16231282,16231414..16231588,16231658..16231840); ID=FBpp0088320; name=Dsp1-PC; parent=FBgn0011764,FBtr0089261; dbxref=FlyBase:FBpp0088320,FlyBase_Annotation_IDs:CG12223-PC,GB_protein:AAF48594.2,REFSEQ:NP_542446,GB_protein:AAF48594; MD5=891c61eae6e1a822323843f98b2ed71e; length=385; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=X:join(16334390..16334413,16336291..16336743,16336851..16337009,16337086..16337249,16337381..16337555,16337625..16337807); ID=FBpp0088318; name=Dsp1-PB; parent=FBgn0011764,FBtr0089259; dbxref=FlyBase:FBpp0088318,FlyBase_Annotation_IDs:CG12223-PB,GB_protein:AAN09396.1,REFSEQ:NP_727961,GB_protein:AAN09396; MD5=891c61eae6e1a822323843f98b2ed71e; length=385; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=X:join(16334390..16334413,16336291..16336743,16336851..16337009,16337086..16337249,16337381..16337555,16337625..16337807); ID=FBpp0088319; name=Dsp1-PA; parent=FBgn0011764,FBtr0089260; dbxref=FlyBase:FBpp0088319,FlyBase_Annotation_IDs:CG12223-PA,GB_protein:AAN09395.1,REFSEQ:NP_727960,GB_protein:AAN09395,FlyMine:FBpp0088319,modMine:FBpp0088319; MD5=891c61eae6e1a822323843f98b2ed71e; length=385; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=X:join(16334390..16334413,16336291..16336743,16336851..16337009,16337086..16337249,16337381..16337555,16337625..16337807); ID=FBpp0088320; name=Dsp1-PC; parent=FBgn0011764,FBtr0089261; dbxref=FlyBase:FBpp0088320,FlyBase_Annotation_IDs:CG12223-PC,GB_protein:AAF48594.2,REFSEQ:NP_542446,GB_protein:AAF48594; MD5=891c61eae6e1a822323843f98b2ed71e; length=385; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=X:join(16334390..16334413,16336291..16336743,16336851..16337009,16337086..16337249,16337381..16337555,16337625..16337807); ID=FBpp0088318; name=Dsp1-PB; parent=FBgn0278608,FBtr0089259; dbxref=FlyBase:FBpp0088318,FlyBase_Annotation_IDs:CG12223-PB,GB_protein:AAN09396.1,REFSEQ:NP_727961,GB_protein:AAN09396; MD5=891c61eae6e1a822323843f98b2ed71e; length=385; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • type=protein; loc=X:join(16334390..16334413,16336291..16336743,16336851..16337009,16337086..16337249,16337381..16337555,16337625..16337807); ID=FBpp0088319; name=Dsp1-PA; parent=FBgn0278608,FBtr0089260; dbxref=FlyBase:FBpp0088319,FlyBase_Annotation_IDs:CG12223-PA,GB_protein:AAN09395.1,REFSEQ:NP_727960,GB_protein:AAN09395,FlyMine:FBpp0088319,modMine:FBpp0088319; MD5=891c61eae6e1a822323843f98b2ed71e; length=385; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • type=protein; loc=X:join(16334390..16334413,16336291..16336743,16336851..16337009,16337086..16337249,16337381..16337555,16337625..16337807); ID=FBpp0088320; name=Dsp1-PC; parent=FBgn0278608,FBtr0089261; dbxref=FlyBase:FBpp0088320,FlyBase_Annotation_IDs:CG12223-PC,GB_protein:AAF48594.2,REFSEQ:NP_542446,GB_protein:AAF48594; MD5=891c61eae6e1a822323843f98b2ed71e; length=385; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Isoform of Q24537, Isoform A of High mobility group protein DSP1 OS=Drosophila melanogaster GN=Dsp1 [DROME.fasta.20160308]
  • FBpp0088318 type=protein; loc=X:join(16334390..16334413,16336291..16336743,16336851..16337009,16337086..16337249,16337381..16337555,16337625..16337807); ID=FBpp0088318; name=Dsp1-PB; parent=FBgn0278608,FBtr0089259; dbxref=FlyBase:FBpp0088318,FlyBase_Annotation_IDs:CG12223-PB,GB_protein:AAN09396.1,REFSEQ:NP_727961,GB_protein:AAN09396; MD5=891c61eae6e1a822323843f98b2ed71e; length=385; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • FBpp0088319 type=protein; loc=X:join(16334390..16334413,16336291..16336743,16336851..16337009,16337086..16337249,16337381..16337555,16337625..16337807); ID=FBpp0088319; name=Dsp1-PA; parent=FBgn0278608,FBtr0089260; dbxref=FlyBase:FBpp0088319,FlyBase_Annotation_IDs:CG12223-PA,GB_protein:AAN09395.1,REFSEQ:NP_727960,GB_protein:AAN09395,FlyMine:FBpp0088319,modMine:FBpp0088319; MD5=891c61eae6e1a822323843f98b2ed71e; length=385; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • FBpp0088320 type=protein; loc=X:join(16334390..16334413,16336291..16336743,16336851..16337009,16337086..16337249,16337381..16337555,16337625..16337807); ID=FBpp0088320; name=Dsp1-PC; parent=FBgn0278608,FBtr0089261; dbxref=FlyBase:FBpp0088320,FlyBase_Annotation_IDs:CG12223-PC,GB_protein:AAF48594.2,REFSEQ:NP_542446,GB_protein:AAF48594; MD5=891c61eae6e1a822323843f98b2ed71e; length=385; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=X:join(16334390..16334413,16336291..16336743,16336851..16337009,16337086..16337249,16337381..16337555,16337625..16337807); ID=FBpp0088318; name=Dsp1-PB; parent=FBgn0278608,FBtr0089259; dbxref=FlyBase:FBpp0088318,FlyBase_Annotation_IDs:CG12223-PB,GB_protein:AAN09396.1,REFSEQ:NP_727961,GB_protein:AAN09396; MD5=891c61eae6e1a822323843f98b2ed71e; length=385; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
  • type=protein; loc=X:join(16334390..16334413,16336291..16336743,16336851..16337009,16337086..16337249,16337381..16337555,16337625..16337807); ID=FBpp0088319; name=Dsp1-PA; parent=FBgn0278608,FBtr0089260; dbxref=FlyBase:FBpp0088319,FlyBase_Annotation_IDs:CG12223-PA,GB_protein:AAN09395.1,REFSEQ:NP_727960,GB_protein:AAN09395,FlyMine:FBpp0088319,modMine:FBpp0088319; MD5=891c61eae6e1a822323843f98b2ed71e; length=385; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
  • type=protein; loc=X:join(16334390..16334413,16336291..16336743,16336851..16337009,16337086..16337249,16337381..16337555,16337625..16337807); ID=FBpp0088320; name=Dsp1-PC; parent=FBgn0278608,FBtr0089261; dbxref=FlyBase:FBpp0088320,FlyBase_Annotation_IDs:CG12223-PC,GB_protein:AAF48594.2,REFSEQ:NP_542446,GB_protein:AAF48594; MD5=891c61eae6e1a822323843f98b2ed71e; length=385; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 385 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEHFHQIQQL AAQQQQQVQQ QQLQQHQVVV QQNQQQAHQN SSNTTAGVGT QQLFTYKMAS  60
   61 SFPNPATTMA QVVATSNAAG TTGYDYRLNM AQAAAAAAVP GSQWWYSAAN QGQVDANTAA 120
  121 QLQHQQQQQQ QQQQQQQQQH QQQQQMQQQQ QQQNVINSAS PMSRVKADAK PRGRMTAYAY 180
  181 FVQTCREEHK KKHPDETVIF AEFSRKCAER WKTMVDKEKK RFHEMAEKDK QRYEAEMQNY 240
  241 VPPKGAVVGR GKKRKQIKDP NAPKRSLSAF FWFCNDERNK VKALNPEFGV GDIAKELGRK 300
  301 WSDVDPEVKQ KYESMAERDK ARYEREMTEY KTSGKIAMSA PSMQASMQAQ AQKAALLAAA 360
  361 AQQQHQQLEE QHDDDDGDGD DDENQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..165] MSA 1.104995 View MSA. No confident structure predictions are available.
    2 View Details [166..385] PSI-BLAST 31.69897 No description for 2gzkA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  0.927928103499335 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.38664561645052 bayes_pls_golite062009
  • DNA binding
    		•  0.37554038880732 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle