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Protein Overview: eas-PE

General Information:
Name(s) found: eas-PE / FBpp0073994 [FlyBase]
Description(s) found:
Found 12 descriptions.
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  • The gene easily shocked is referred to in FlyBase by the symbol Dmel\eas (CG3525, FBgn0000536). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:16172360..16179654. It has the cytological map location 14B7. There is experimental evidence that it has the molecular function</span>: ethanolamine kinase activity. There is experimental evidence that it is involved in the biological process</span>: response to mechanical stimulus; asymmetric neuroblast division; brain development; mushroom body development; mechanosensory behavior. 26 alleles are reported. The phenotypes of these alleles are annotated with: mushroom body beta'-lobe; calyx of mushroom body; mushroom body beta-lobe; mushroom body alpha-lobe; mushroom body alpha'-lobe. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 518 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: mechanosensory behavior [IMP]
    long-term memory [TAS]
    phosphatidylethanolamine biosynthetic process [NAS]
    habituation [TAS]
    mushroom body development [IMP][TAS]
    asymmetric neuroblast division [IMP]
    brain development [IMP]
    phosphorylation [NAS]
    associative learning [TAS]
    response to mechanical stimulus [IGI][IMP]
    Molecular Function: ethanolamine kinase activity [IDA][NAS]
    choline kinase activity [NAS][TAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGTETKSNSY TGQISTSGGN PKVMKDSLSL VRQTVNQQTL SLSQSNQVQN QLNSHSNSNS  60
   61 YPNPSGSENK NENEQNSRDI RAKPEDKSRK EAIVPFVPIF VEEADVIQGA KELLKVIRPT 120
  121 WDLSHVEFKI RVVPQIEDRY PAQNAMVMMT LYSFTDGITN KLVGCFHKEI SKLNDENGGS 180
  181 YLPIKTQGLS PVQSEDPVII EKEDDDEFTD DRAADDGSPV QYSDNVVLVR IYGNKTDLLI 240
  241 DRKAETQNFL LLHTYGLAPS LYATFKNGLV YEYVPGTTLN TDSVLCPEIW PLVARRMAEM 300
  301 HRKVRKHGDS SATKPMPMIW KKTQSFLDLV PERFSDAEKH KRVKETFLPI GRLREEFNKL 360
  361 YEYLEALDSP IVFSHNDLLL GNVIYTQSLN TVNFIDYEYA DYNFQAFDIG NHFAEMCGVD 420
  421 EVDYSRYPKR EFQLQWLRVY LEEYLQRSNI QNDEVELLYV QVNQFALASH IFWTVWSLLQ 480
  481 AEHSTIDFDY VGYAFLRYNE YLARKVEFLS LTAAKNNK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..89] deduced N/A No confident structure predictions are available.
    2 View Details [90..132] MSA 1.095996 View MSA. No confident structure predictions are available.
    3 View Details [133..518] PSI-BLAST 52.522879 No description for 2ig7A was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle