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Protein Overview: CG9172-PB, FBpp0...

General Information:
Name(s) found: FBpp0309363 [FlyBase]
CG9172-PB / FBpp0073950 [FlyBase]
CG9172-PA / FBpp0073949 [FlyBase]
Description(s) found:
Found 38 descriptions.
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  • type=protein; loc=X:complement(15880044..15880709); ID=FBpp0309363; name=CG9172-PC; parent=FBgn0030718,FBtr0340417; dbxref=FlyBase:FBpp0309363,FlyBase_Annotation_IDs:CG9172-PC; MD5=3309fc94bfe314740e66f80b298f9fa9; length=221; release=r5.56; species=Dmel; [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\CG9172 (CG9172, FBgn0030718). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:15879877..15880791. It has the cytological map location 14A5. Based on sequence similarity, it is predicted to have molecular function</span>: NADH dehydrogenase activity; NADH dehydrogenase (ubiquinone) activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: mitochondrial electron transport, NADH to ubiquinone. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\CG9172 (CG9172, FBgn0030718). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:15879877..15880791. It has the cytological map location 14A5. Based on sequence similarity, it is predicted to have molecular function</span>: NADH dehydrogenase activity; NADH dehydrogenase (ubiquinone) activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: mitochondrial electron transport, NADH to ubiquinone. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 221 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial respiratory chain complex I [ISS]
    Biological Process: mitochondrial electron transport, NADH to ubiquinone [ISS]
    Molecular Function: NADH dehydrogenase activity [ISS]
    quinone binding [IEA]
    NADH dehydrogenase (ubiquinone) activity [ISS]
    4 iron, 4 sulfur cluster binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRSAMMSST LSRALQKATQ TPNASISALP ALNLALVRQQ QTLPVAEVAQ NLPKKGYSPF  60
   61 GTKQSSVAEW SLARLDDLLN WGRKGSIWPL TFGLACCAVE MMHIAAPRYD MDRYGVVFRA 120
  121 SPRQADVIIV AGTLTNKMAP ALRKVYDQMP EPRWVISMGS CANGGGYYHY SYSVVRGCDR 180
  181 IIPVDIYVPG CPPTAEALMY GVLQLQKKVK RMKTLQMWYR K

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..221] PSI-BLAST 53.39794 Crystal structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • NADH dehydrogenase activity
    		•  13.9361001493201 bayes_pls_golite062009
  • NADH dehydrogenase (quinone) activity
    		•  12.823760326196 bayes_pls_golite062009
  • NADH dehydrogenase (ubiquinone) activity
    		•  12.8237449606378 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
    		•  12.2946357205778 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH
    		•  11.5463682902166 bayes_pls_golite062009
  • oxidoreductase activity
    		•  6.65509281399906 bayes_pls_golite062009
  • oxidoreduction-driven active transmembrane transporter activity
    		•  3.12366321374445 bayes_pls_golite062009
  • 4 iron, 4 sulfur cluster binding
    		•  2.30490418238429 bayes_pls_golite062009
  • catalytic activity
    		•  1.41356903593784 bayes_pls_golite062009
  • iron-sulfur cluster binding
    		•  1.3943220140881 bayes_pls_golite062009
  • metal cluster binding
    		•  1.3943220140881 bayes_pls_golite062009
  • binding
    		•  1.12857450780286 bayes_pls_golite062009
  • protein binding
    		•  0.241603585422086 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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