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Protein Overview: FBpp0308531, Chc...

General Information:
Name(s) found: FBpp0308531 [FlyBase]
Chc-PF / FBpp0111710 [FlyBase]
Chc-PE / FBpp0111709 [FlyBase]
Chc-PD / FBpp0089398 [FlyBase]
Chc-PC / FBpp0089397 [FlyBase]
Chc-PB / FBpp0073967 [FlyBase]
Chc-PA / FBpp0073966 [FlyBase]
Description(s) found:
Found 90 descriptions.
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  • type=protein; loc=X:complement(15722305..15722535,15722596..15722682,15722749..15722915,15722985..15727286,15727525..15727732,15728156..15728197); ID=FBpp0308531; name=Chc-PG; parent=FBgn0000319,FBtr0339445; dbxref=FlyBase:FBpp0308531,FlyBase_Annotation_IDs:CG9012-PG; MD5=7e1eb52b2f9f7ecf7169e3aba6430dd5; length=1678; release=r5.56; species=Dmel; [FlyBase]
  • The gene Clathrin heavy chain is referred to in FlyBase by the symbol Dmel\Chc (CG9012, FBgn0000319). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:15722019..15729507. It has the cytological map location 13F5-13F7. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: structural molecule activity; protein binding. There is experimental evidence that it is involved in the biological process</span>: sperm individualization; dsRNA transport; liquid clearance, open tracheal system; regulation of tube length, open tracheal system; extracellular matrix organization. 19 alleles are reported. The phenotypes of these alleles are annotated with: embryonic tracheal system; primary spermatocyte cyst; major mitochondrial derivative; minor mitochondrial derivative; spermatozoon. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase]
  • The gene Clathrin heavy chain is referred to in FlyBase by the symbol Dmel\Chc (CG9012, FBgn0000319). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:15722019..15729507. It has the cytological map location 13F5-13F7. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: structural molecule activity; protein binding. There is experimental evidence that it is involved in the biological process</span>: sperm individualization; dsRNA transport; liquid clearance, open tracheal system; regulation of tube length, open tracheal system; extracellular matrix organization. 19 alleles are reported. The phenotypes of these alleles are annotated with: embryonic tracheal system; primary spermatocyte cyst; major mitochondrial derivative; minor mitochondrial derivative; spermatozoon. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase]
  • The gene Clathrin heavy chain is referred to in FlyBase by the symbol Dmel\Chc (CG9012, FBgn0000319). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:15722019..15729507. It has the cytological map location 13F5-13F7. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: structural molecule activity; protein binding. There is experimental evidence that it is involved in the biological process</span>: sperm individualization; dsRNA transport; liquid clearance, open tracheal system; regulation of tube length, open tracheal system; extracellular matrix organization. 19 alleles are reported. The phenotypes of these alleles are annotated with: embryonic tracheal system; primary spermatocyte cyst; major mitochondrial derivative; minor mitochondrial derivative; spermatozoon. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase]
  • The gene Clathrin heavy chain is referred to in FlyBase by the symbol Dmel\Chc (CG9012, FBgn0000319). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:15722019..15729507. It has the cytological map location 13F5-13F7. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: structural molecule activity; protein binding. There is experimental evidence that it is involved in the biological process</span>: sperm individualization; dsRNA transport; liquid clearance, open tracheal system; regulation of tube length, open tracheal system; extracellular matrix organization. 19 alleles are reported. The phenotypes of these alleles are annotated with: embryonic tracheal system; primary spermatocyte cyst; major mitochondrial derivative; minor mitochondrial derivative; spermatozoon. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase]
  • The gene Clathrin heavy chain is referred to in FlyBase by the symbol Dmel\Chc (CG9012, FBgn0000319). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:15722019..15729507. It has the cytological map location 13F5-13F7. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: structural molecule activity; protein binding. There is experimental evidence that it is involved in the biological process</span>: sperm individualization; dsRNA transport; liquid clearance, open tracheal system; regulation of tube length, open tracheal system; extracellular matrix organization. 19 alleles are reported. The phenotypes of these alleles are annotated with: embryonic tracheal system; primary spermatocyte cyst; major mitochondrial derivative; minor mitochondrial derivative; spermatozoon. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase]
  • The gene Clathrin heavy chain is referred to in FlyBase by the symbol Dmel\Chc (CG9012, FBgn0000319). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:15722019..15729507. It has the cytological map location 13F5-13F7. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: structural molecule activity; protein binding. There is experimental evidence that it is involved in the biological process</span>: sperm individualization; dsRNA transport; liquid clearance, open tracheal system; regulation of tube length, open tracheal system; extracellular matrix organization. 19 alleles are reported. The phenotypes of these alleles are annotated with: embryonic tracheal system; primary spermatocyte cyst; major mitochondrial derivative; minor mitochondrial derivative; spermatozoon. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1678 amino acids

    Gene Ontology:
    Cellular Component: clathrin coat of synaptic vesicle [NAS]
    lipid particle [IDA]
    synaptic vesicle [TAS]
    coated pit [TAS]
    clathrin coat of trans-Golgi network vesicle [IEA]
    clathrin coat of coated pit [IEA][NAS]
    cytoplasmic vesicle [IDA]
    clathrin vesicle coat [TAS]
    coated vesicle [TAS]
    plasma membrane [IDA]
    Biological Process: liquid clearance, open tracheal system [IMP]
    sperm individualization [IMP]
    vesicle-mediated transport [IEA]
    synaptic vesicle coating [NAS][TAS]
    extracellular matrix organization [IMP]
    intracellular protein transport [IEA]
    regulation of tube length, open tracheal system [IMP]
    neurotransmitter secretion [NAS]
    dsRNA transport [IMP]
    Molecular Function: protein binding [IEA]
    structural molecule activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTQPLPIRFQ EHLQLTNVGI NANSFSFSTL TMESDKFICV REKVNDTAQV VIIDMNDATN  60
   61 PTRRPISADS AIMNPASKVI ALKAQKTLQI FNIEMKSKMK AHTMNEDVVF WKWISLNTLA 120
  121 LVTETSVFHW SMEGDSMPQK MFDRHSSLNG CQIINYRCNA SQQWLLLVGI SALPSRVAGA 180
  181 MQLYSVERKV SQAIEGHAAS FATFKIDANK EPTTLFCFAV RTATGGKLHI IEVGAPPNGN 240
  241 QPFAKKAVDV FFPPEAQNDF PVAMQVSAKY DTIYLITKYG YIHLYDMETA TCIYMNRISA 300
  301 DTIFVTAPHE ASGGIIGVNR KGQVLSVTVD EEQIIPYINT VLQNPDLALR MAVRNNLAGA 360
  361 EDLFVRKFNK LFTAGQYAEA AKVAALAPKA ILRTPQTIQR FQQVQTPAGS TTPPLLQYFG 420
  421 ILLDQGKLNK FESLELCRPV LLQGKKQLCE KWLKEEKLEC SEELGDLVKA SDLTLALSIY 480
  481 LRANVPNKVI QCFAETGQFQ KIVLYAKKVN YTPDYVFLLR SVMRSNPEQG AGFASMLVAE 540
  541 EEPLADINQI VDIFMEHSMV QQCTAFLLDA LKHNRPAEGA LQTRLLEMNL MSAPQVADAI 600
  601 LGNAMFTHYD RAHIAQLCEK AGLLQRALEH YTDLYDIKRA VVHTHMLNAE WLVSFFGTLS 660
  661 VEDSLECLKA MLTANLRQNL QICVQIATKY HEQLTNKALI DLFEGFKSYD GLFYFLSSIV 720
  721 NFSQDPEVHF KYIQAACKTN QIKEVERICR ESNCYNPERV KNFLKEAKLT DQLPLIIVCD 780
  781 RFDFVHDLVL YLYRNNLQKY IEIYVQKVNP SRLPVVVGGL LDVDCSEDII KNLILVVKGQ 840
  841 FSTDELVEEV EKRNRLKLLL PWLESRVHEG CVEPATHNAL AKIYIDSNNN PERYLKENQY 900
  901 YDSRVVGRYC EKRDPHLACV AYERGLCDRE LIAVCNENSL FKSEARYLVG RRDAELWAEV 960
  961 LSESNPYKRQ LIDQVVQTAL SETQDPDDIS VTVKAFMTAD LPNELIELLE KIILDSSVFS1020
 1021 DHRNLQNLLI LTAIKADRTR VMDYINRLEN YDAPDIANIA ISNQLYEEAF AIFKKFDVNT1080
 1081 SAIQVLIDQV NNLERANEFA ERCNEPAVWS QLAKAQLQQG LVKEAIDSYI KADDPSAYVD1140
 1141 VVDVASKVES WDDLVRYLQM ARKKARESYI ESELIYAYAR TGRLADLEEF ISGPNHADIQ1200
 1201 KIGNRCFSDG MYDAAKLLYN NVSNFARLAI TLVYLKEFQG AVDSARKANS TRTWKEVCFA1260
 1261 CVDAEEFRLA QMCGLHIVVH ADELEDLINY YQNRGYFDEL IALLESALGL ERAHMGMFTE1320
 1321 LAILYSKFKP SKMREHLELF WSRVNIPKVL RAAESAHLWS ELVFLYDKYE EYDNAVLAMM1380
 1381 AHPTEAWREG HFKDIITKVA NIELYYKAIE FYLDFKPLLL NDMLLVLAPR MDHTRAVSYF1440
 1441 SKTGYLPLVK PYLRSVQSLN NKAINEALNG LLIDEEDYQG LRNSIDGFDN FDNIALAQKL1500
 1501 EKHELTEFRR IAAYLYKGNN RWKQSVELCK KDKLYKDAME YAAESCKQDI AEELLGWFLE1560
 1561 RDAYDCFAAC LYQCYDLLRP DVILELAWKH KIVDFAMPYL IQVLREYTTK VDKLELNEAQ1620
 1621 REKEDDSTEH KNIIQMEPQL MITAGPAMGI PPQYAQNYPP GAATVTAAGG RNMGYPYL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..1678] PSI-BLAST 1000.0 Clathrin D6 Coat


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.86

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle