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Protein Overview: CG8509-PA

General Information:
Name(s) found: CG8509-PA / FBpp0073913 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG8509 (CG8509, FBgn0030696). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:15703588..15704980. It has the cytological map location 13F1. Based on sequence similarity, it is predicted to have molecular function</span>: protein tyrosine phosphatase activator activity. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 432 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: protein tyrosine phosphatase activator activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNKLGYDVT DPTVQLLRAS AFMQNGPVKQ VRSLEDLDRW VRSQAYYDII AYISNTSKAI  60
   61 QGHRLTQTFP VTEQMRRLSE IFDGLDHLIV EHTPKIEDSY LALPFGQVRS KAYRTWMREM 120
  121 YQHVFSKLDE AINVNCKHIN ELGQYLRRSF GNGNTLDFGP ANELMFLFFL CGLFRAGILL 180
  181 AKDTVAAALM LFNRYVNVVR RLISTYGLTI AKDPACTIED YYFLPYLWGA AQLSVDSPFS 240
  241 PMQCEQGKIM DNYRQDFMML EIIDHLQKTR SGPLSRVALQ LWSILSIPTW PQVYRGLERN 300
  301 YIDHVLSSFG TVEQAIFCEL MSFEAVVPIM PLQRAHLGTH LIVDEKENED ELEQKYGENR 360
  361 WSLSPPVSRY VSMEPESFLG FQASKTHNKS KESEDERLWM MRQLVDENDP NSDMFFPDRE 420
  421 VKGRDSLTSF AN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..329] PSI-BLAST 146.0 No description for 2hv6A was found.
    2 View Details [330..432] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein phosphatase 2A binding
    		•  8.91440374532471 bayes_pls_golite062009
  • protein phosphatase type 2A regulator activity
    		•  8.6639960888548 bayes_pls_golite062009
  • phosphatase activator activity
    		•  8.3056988507343 bayes_pls_golite062009
  • protein tyrosine phosphatase activator activity
    		•  8.25208483660706 bayes_pls_golite062009
  • phosphatase regulator activity
    		•  6.19500533578098 bayes_pls_golite062009
  • protein phosphatase regulator activity
    		•  6.15684302555811 bayes_pls_golite062009
  • hydrolase activity
    		•  2.45059495047304 bayes_pls_golite062009
  • protein phosphatase binding
    		•  2.00937322119814 bayes_pls_golite062009
  • phosphatase binding
    		•  1.91058768875586 bayes_pls_golite062009
  • binding
    		•  1.8791829282582 bayes_pls_golite062009
  • enzyme regulator activity
    		•  1.7601888817048 bayes_pls_golite062009
  • protein binding
    		•  1.54296590753075 bayes_pls_golite062009
  • enzyme binding
    		•  0.93814259527019 bayes_pls_golite062009
  • enzyme activator activity
    		•  0.877491580866805 bayes_pls_golite062009
  • protein dimerization activity
    		•  0.382201469725949 bayes_pls_golite062009
  • catalytic activity
    		•  0.262417313750414 bayes_pls_golite062009
  • receptor binding
    		•  0.23629695620438 bayes_pls_golite062009
  • protein homodimerization activity
    		•  0.0723700055105033 bayes_pls_golite062009
  • ATP binding
    		•  0.00395016899365508 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.86

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle