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Protein Overview: Flo-2-PA, Flo-2-...

General Information:
Name(s) found: FBpp0303249 [FlyBase]
Flo-2-PE / FBpp0073768 [FlyBase]
Flo-2-PA / FBpp0073766 [FlyBase]
Description(s) found:
Found 42 descriptions.
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  • type=protein; loc=X:join(14735004..14735052,14818259..14818446,14819679..14819717,14820799..14820907,14824780..14825347,14825835..14826018,14826081..14826260); ID=FBpp0303249; name=Flo2-PK; parent=FBgn0264078,FBtr0330216; dbxref=REFSEQ:NP_001259555,GB_protein:AGB95397,FlyBase:FBpp0303249,FlyBase_Annotation_IDs:CG32593-PK; MD5=d693f1fe4142b61b1925783f125500ac; length=438; release=r5.56; species=Dmel; [FlyBase]
  • The gene flotillin 2 is referred to in FlyBase by the symbol Dmel\Flo-2 (CG32593, FBgn0024753). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:14733411..14827616. It has the cytological map location 12F5-13A1. There is experimental evidence that it has the molecular function</span>: structural molecule activity. It is reported to be involved in the biological process</span>: cell adhesion. 25 alleles are reported. The phenotypes of these alleles are annotated with: eye; macrochaeta; ocellus; wing. It has 8 annotated transcripts and 8 annotated polypeptides. [FlyBase]
  • The gene flotillin 2 is referred to in FlyBase by the symbol Dmel\Flo-2 (CG32593, FBgn0024753). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:14733411..14827616. It has the cytological map location 12F5-13A1. There is experimental evidence that it has the molecular function</span>: structural molecule activity. It is reported to be involved in the biological process</span>: cell adhesion. 25 alleles are reported. The phenotypes of these alleles are annotated with: eye; macrochaeta; ocellus; wing. It has 8 annotated transcripts and 8 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 438 amino acids

    Gene Ontology:
    Cellular Component: flotillin complex [NAS]
    Biological Process: cell adhesion [NAS]
    Molecular Function: structural molecule activity [IEP]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGNIHTTGPN EALIVSGGCC GSTKKRTIVG GWAWAWWLVT DVQRLSLNVM TLNPMCENVE  60
   61 TSQGVPLTVT GVAQCKIMKS SSYKQTDYHN DEADELLGTA SEQFLGKSVK EIKQTILQTL 120
  121 EGHLRAILGT LTVEEVYKDR DQFAALVREV AAPDVGRMGI EILSFTIKDV YDDVQYLASL 180
  181 GKAQTAVVKR DADAGVAEAN RDAGIREAEC EKSAMDVKYS TDTKIEDNTR MYKLQKANFD 240
  241 QEINTAKAES QLAYELQAAK IRQRIRNEEI QIEVVERRKQ IEIESQEVQR KDRELTGTVK 300
  301 LPAEAEAFRL QTLAQAKQCQ TIEGARAEAE RIRKIGSAEA HAIELVGKAE AERMRMKAHV 360
  361 YKQYGDAAIM NIVLESLPKI AAEVAAPLAK TDEIVLIGGN DNITNDVTRL VAQLPPSINA 420
  421 LTGVDLSKVL SKIPGAKA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..169] PSI-BLAST 19.154902 Solution Structure of the Band 7 Domain of the mouse Flotillin 2 Protein
    2 View Details [170..438] PSI-BLAST 4.221849 Heavy meromyosin subfragment

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.23605224291772 bayes_pls_golite062009
  • protein binding
    		•  0.792911224088066 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle