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Protein Overview: Syt12-PA, FBpp03...

General Information:
Name(s) found: FBpp0303988 [FlyBase]
Syt12-PA / FBpp0073598 [FlyBase]
Description(s) found:
Found 25 descriptions.
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  • type=protein; loc=X:join(13257325..13257513,13257617..13258905,13258964..13259108,13259173..13259526,13259608..13259994); ID=FBpp0303988; name=Syt12-PB; parent=FBgn0261085,FBtr0331598; dbxref=REFSEQ:NP_001259513,GB_protein:AGB95355,FlyBase:FBpp0303988,FlyBase_Annotation_IDs:CG10617-PB; MD5=880287bbf5eb92b4e8dd5a5cfdd99706; length=787; release=r5.56; species=Dmel; [FlyBase]
  • The gene Synaptotagmin 12 is referred to in FlyBase by the symbol Dmel\Syt12 (CG10617, FBgn0261085). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:13253283..13262214. It has the cytological map location 11F1. Based on sequence similarity, it is predicted to have molecular function</span>: calcium-dependent phospholipid binding. Based on sequence similarity, it is predicted to be involved in the biological process</span>: neurotransmitter secretion. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 787 amino acids

    Gene Ontology:
    Cellular Component: synaptic vesicle [ISS]
    Biological Process: neurotransmitter secretion [ISS]
    Molecular Function: calcium-dependent phospholipid binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMSFTITLAL LLLAVLILGI LFACHCLGPR AANWMRMRSS KEEKIGLSNH KQKLFHANGY  60
   61 MASIQSGSEF LLSTSGSFKR FDTIDKEDYN RSQQTHQTHL FLMNGGGAVS ITGSSSALQA 120
  121 TTAMWHLPRS GIKIPPPPDR PAPSPNSAAA AGKTVTFSLS QVNEVIMPGE QVTSNDQERR 180
  181 SCLRQNGGTA GGAGGGGVLP QPLEAPPPPR LTASTSVNLS GTAIPRPIAK RQVSTQPANN 240
  241 SGCQPEQTVV TPMREGERKA PALKRRNSST NPFLCESTEQ IPSNPISEPL NATVASLEKT 300
  301 TISTSECTPI TAPLETPNGP ISTDTPSTIH HNGNPFVERE SLSSRLLKIH NTTNPFTGLS 360
  361 QRVKGPHLLQ KTISEDYLFR KLGVNCPMAN GNGTGPGSGH VNGNGNGTWS FGRSLLRQDS 420
  421 TLSLGMGLGR RNSSQVSLDS HAGSVPGSMD GINLERAISC DSVTSDSTLF LDQLDQPYTQ 480
  481 ITGYLCVGLN YDQMSISNEG MELTVSVLEA KGLICPFSVE SLDTFVRIYL VPDHPGAMQT 540
  541 KVVKGTLTPS YNESFDFWLH KRQARHSLWF HLYHNGPAHT LIGEAEMEIG EMPRPITTWI 600
  601 PLSDSRKCNA RWGELMFSLS YLPTAERLTI VVVKARNLKL DGEQPAPESA ETVHSVFVKV 660
  661 YLMDKDRKVL KKRTSLKRKD RSPIFNESMI FSVPPPSLTT TQLRVTVFGV TTSGVTPLGH 720
  721 IVAGSCAVGK GLRHWHQMLS SLRKPVAMWH VLRRAVNQPI FTGGAEAVVA AMQNTLQRST 780
  781 AKRNSIV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..280] MSA 6.219997 View MSA. No confident structure predictions are available.
    2 View Details [281..479] deduced N/A No confident structure predictions are available.
    3 View Details [480..787] PSI-BLAST 89.39794 Synaptogamin I


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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