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Protein Overview: Sptr-PA

General Information:
Name(s) found: Sptr-PA / FBpp0071184 [FlyBase]
Description(s) found:
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  • gi|7290936|gb|AAF46376.1| sepiapterin reductase [Drosophila melanogaster] [NCBI NR]
  • gi|6006815|gb|AAF00619.1|AF167284_1 sepiapterin reductase [Drosophila melanogaster] [NCBI NR]
  • gi|3548968|gb|AAD12760.1| sepiapterin reductase; SR [Drosophila melanogaster] [NCBI NR]
  • gi|24640597|ref|NP_727265.1| sepiapterin reductase [Drosophila melanogaster] [NCBI NR]
  • gi|223968827|emb|CAR94144.1| CG12117-PA [Drosophila melanogaster] [NCBI NR]
  • gi|223968819|emb|CAR94140.1| CG12117-PA [Drosophila melanogaster] [NCBI NR]
  • gi|223968815|emb|CAR94138.1| CG12117-PA [Drosophila melanogaster] [NCBI NR]
  • gi|223968811|emb|CAR94136.1| CG12117-PA [Drosophila melanogaster] [NCBI NR]
  • gi|223968809|emb|CAR94135.1| CG12117-PA [Drosophila melanogaster] [NCBI NR]
  • gi|21429826|gb|AAM50591.1| GH04031p [Drosophila melanogaster] [NCBI NR]
  • gi|194353342|emb|CAQ53463.1| CG12117-PA [Drosophila melanogaster] [NCBI NR]
  • gi|194353332|emb|CAQ53458.1| CG12117-PA [Drosophila melanogaster] [NCBI NR]
  • gi|194353330|emb|CAQ53457.1| CG12117-PA [Drosophila melanogaster] [NCBI NR]
  • gi|194353326|emb|CAQ53455.1| CG12117-PA [Drosophila melanogaster] [NCBI NR]
  • gi|194353322|emb|CAQ53453.1| CG12117-PA [Drosophila melanogaster] [NCBI NR]
  • The gene Sepiapterin reductase is referred to in FlyBase by the symbol Dmel\Sptr (CG12117, FBgn0014032). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:8357338..8359030. It has the cytological map location 7E11. Based on sequence similarity, it is predicted to have molecular function</span>: sepiapterin reductase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: tetrahydrobiopterin biosynthetic process; oxidation reduction. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG12117-PA translation from_gene[CG12117 Sptr FBgn0014032] seq_release:3 mol_weight=29232 cds_boundaries:(X:8,202,470..8,203,252[-]) aa_length:261 transcript_info:[CG12117-RA seq_release:3] gene_info:[gene symbol:Sptr FBgn0014032 gene_boundaries:(X:8, [hmr_yeast5_DM3-1_pombe.fasta]
  • (O76752) SPTR protein (GH04031p) [DrosMelano7227.FASTAC.txt]
  • (AE003444) Sptr gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG12117-PA [Drosophila melanogaster]gi|21429826|gb|AAM50591.1| GH04031p [Drosophila melanogaster]gi|24640597|ref|NP_727265.1| CG12117-PA [Drosophila melanogaster]gi|3548968|gb|AAD12760.1| sepiapterin reductase; SR [Drosophila melanogaster]gi|6006815|g [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=X:complement(8357554..8358339); ID=FBpp0071184; name=Sptr-PA; parent=FBgn0014032,FBtr0071241; dbxref=FlyBase:FBpp0071184,FlyBase_Annotation_IDs:CG12117-PA,GB_protein:AAF46376.1,REFSEQ:NP_727265,GB_protein:AAF46376; MD5=a96790f73208d9a906 [fly-100309-contam.fasta]
  • GH04031p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Sepiapterin reductase CG12117-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • sepiapterin reductase; SR [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG12117-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • sepiapterin reductase [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=X:complement(8357554..8358339); ID=FBpp0071184; name=Sptr-PA; parent=FBgn0014032,FBtr0071241; dbxref=FlyBase:FBpp0071184,FlyBase_Annotation_IDs:CG12117-PA,GB_protein:AAF46376.1,REFSEQ:NP_727265,GB_protein:AAF46376; MD5=a96790f73208d9a906e867f2d5326c44; length=261; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=X:complement(8357554..8358339); ID=FBpp0071184; name=Sptr-PA; parent=FBgn0014032,FBtr0071241; dbxref=FlyBase:FBpp0071184,FlyBase_Annotation_IDs:CG12117-PA,GB_protein:AAF46376.1,REFSEQ:NP_727265,GB_protein:AAF46376; MD5=a96790f73208d9a906e867f2d5326c44; length=261; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • CG12117-PA OS=Drosophila melanogaster GN=Sptr PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=X:complement(8357554..8358339); ID=FBpp0071184; name=Sptr-PA; parent=FBgn0014032,FBtr0071241; dbxref=FlyBase:FBpp0071184,FlyBase_Annotation_IDs:CG12117-PA,GB_protein:AAF46376.1,REFSEQ:NP_727265,GB_protein:AAF46376,FlyMine:FBpp0071184,modMine:FBpp0071184; MD5=a96790f73208d9a906e867f2d5326c44; length=261; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=X:complement(8463521..8464306); ID=FBpp0071184; name=Sptr-PA; parent=FBgn0014032,FBtr0071241; dbxref=FlyBase:FBpp0071184,FlyBase_Annotation_IDs:CG12117-PA,GB_protein:AAF46376.1,REFSEQ:NP_727265,GB_protein:AAF46376,FlyMine:FBpp0071184,modMine:FBpp0071184; MD5=a96790f73208d9a906e867f2d5326c44; length=261; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=X:complement(8463521..8464306); ID=FBpp0071184; name=Sptr-PA; parent=FBgn0014032,FBtr0071241; dbxref=FlyBase:FBpp0071184,FlyBase_Annotation_IDs:CG12117-PA,GB_protein:AAF46376.1,REFSEQ:NP_727265,GB_protein:AAF46376,FlyMine:FBpp0071184,modMine:FBpp0071184; MD5=a96790f73208d9a906e867f2d5326c44; length=261; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • CG12117-PA OS=Drosophila melanogaster GN=Sptr PE=1 SV=1 [DROME.fasta.20160308]
  • FBpp0071184 type=protein; loc=X:complement(8463521..8464306); ID=FBpp0071184; name=Sptr-PA; parent=FBgn0014032,FBtr0071241; dbxref=FlyBase:FBpp0071184,FlyBase_Annotation_IDs:CG12117-PA,GB_protein:AAF46376.1,REFSEQ:NP_727265,GB_protein:AAF46376,FlyMine:FBpp0071184,modMine:FBpp0071184; MD5=a96790f73208d9a906e867f2d5326c44; length=261; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=X:complement(8463521..8464306); ID=FBpp0071184; name=Sptr-PA; parent=FBgn0014032,FBtr0071241; dbxref=FlyBase:FBpp0071184,FlyBase_Annotation_IDs:CG12117-PA,GB_protein:AAF46376.1,REFSEQ:NP_727265,GB_protein:AAF46376,UniProt/TrEMBL:O76752,FlyMine:FBpp0071184,modMine:FBpp0071184; MD5=a96790f73208d9a906e867f2d5326c44; length=261; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 261 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: tetrahydrobiopterin biosynthetic process [IEA]
    oxidation reduction [IEA]
    Molecular Function: sepiapterin reductase activity [IDA][ISS]
    binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDLKQRTYLL VTGASRGIGR EFAQQLAKRI KAEGSMVTLL GRNQTLLQES KAEIVATVPD  60
   61 LSVQTYSLEL ETAKTEDFTK ILEASGGKNN FERAIVIHNA GTVGDTSKRA KEIGDTDFLQ 120
  121 RYYHSNVFSA ISLNCEFMRV FKGIPKLVVN LSTLAAIAPI SSMAHYCTVK AAREMYFRVL 180
  181 ATEESAEDTL VLNYAPGVID TQMTVQVQRE AHDPAVVAMF REQRESKTML TPAQTTERFI 240
  241 KVLEAFKFKS GDHVDYRDEQ F

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..261] PSI-BLAST 70.154902 No description for 2p68A was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.80

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle