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Protein Overview: GIIIspla2-PA

General Information:
Name(s) found: GIIIspla2-PA / FBpp0071110 [FlyBase]
Description(s) found:
Found 12 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\GIIIspla2 (CG1583, FBgn0030013). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:8051580..8053072. It has the cytological map location 7D16-7D17. Based on sequence similarity, it is predicted to have molecular function</span>: phospholipase A2 activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: lipid catabolic process; phospholipid metabolic process. 9 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 272 amino acids

    Gene Ontology:
    Cellular Component: extracellular region [IEA]
    Biological Process: lipid catabolic process [IEA]
    phospholipid metabolic process [IEA]
    Molecular Function: phospholipase A2 activity [ISS]
    calcium ion binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MACADAGQCE HARFVLAAVG EHIKRQCFSD WRAISYGHRT LKKRKAERKQ TELNTMWIAN  60
   61 ERTICALMPL VILATWQLCL LPGTDAKHLA IRLRDPQSEI ESETVPLAHV HSHSHTDESG 120
  121 VRGAAAVHRR ERRQLSDWLI APNTRWCGRG NLANGTYNDL GGASKADKCC RKHDHCKMWI 180
  181 DGMSNRYDLF NYRPYTLSHC SCDLRFRTCL KMAGDEDANA IGKLFFNVVQ TQCFGLKAET 240
  241 VCVQRGGSGK ETDPCLKEEV RHKAFLRDNK RF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..123] deduced N/A No confident structure predictions are available.
    2 View Details [124..272] PSI-BLAST 50.045757 CRYSTAL STRUCTURE OF BEE-VENOM PHOSPHOLIPASE A2 IN A COMPLEX WITH A TRANSITION-STATE ANALOGUE


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.75

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle