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Protein Overview: nullo-PB

General Information:
Name(s) found: nullo-PB / FBpp0288840 [FlyBase]
Description(s) found:
Found 19 descriptions.
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  • The gene nullo is referred to in FlyBase by the symbol Dmel\nullo (CG14426, FBgn0004143). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:6943511..6944354. It has the cytological map location 6F1. Based on sequence similarity, it is predicted to have molecular function</span>: actin binding. There is experimental evidence that it is involved in the biological process</span>: regulation of cell shape; morphogenesis of embryonic epithelium; cell-cell junction assembly. 25 alleles are reported. The phenotypes of these alleles are annotated with: embryonic/first instar larval cuticle; zonula adherens; cleavage stage embryo; spot adherens junction; ventral furrow. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 213 amino acids

    Gene Ontology:
    Cellular Component: adherens junction [TAS]
    cell-cell junction [TAS]
    actin filament [NAS]
    Biological Process: regulation of cell shape [IMP]
    cell-cell junction assembly [IMP]
    cytokinesis, actomyosin contractile ring assembly [NAS]
    protein localization [NAS]
    cytokinesis [TAS]
    morphogenesis of embryonic epithelium [IMP]
    cellularization [NAS][TAS]
    actin cytoskeleton organization [NAS]
    Molecular Function: actin binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGSTHSAEKV KSVEDSTSPA NPGIFCTPLP GFISNIQRLV LRKLSISARK QKRLNKRSKH  60
   61 LLRPMPRCSS FGSCGTLLTP TKKSASNIAD RRYAQWKCSF EHLAQKQPRL HDISEAMTGQ 120
  121 TTPRGFPSHT DPKRCLMVMD SSSPESPLYD MVGGQKVRRR LSLRSHALVR RPSARQKAEQ 180
  181 AKLDAQFQRD LRDLEDYYGG FHFAQRRERL VKV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..213] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.93

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle