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Protein Overview: inx2-PC, FBpp030...

General Information:
Name(s) found: FBpp0304593 [FlyBase]
inx2-PC / FBpp0291074 [FlyBase]
inx2-PB / FBpp0070966 [FlyBase]
inx2-PA / FBpp0070965 [FlyBase]
Description(s) found:
Found 55 descriptions.
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  • type=protein; loc=X:6893162..6894265; ID=FBpp0304593; name=Inx2-PD; parent=FBgn0027108,FBtr0332314; dbxref=REFSEQ:NP_001259301,GB_protein:AGB95146,FlyBase:FBpp0304593,FlyBase_Annotation_IDs:CG4590-PD; MD5=371f9f9aa24b99a80f5e9c6d30eab4e3; length=367; release=r5.56; species=Dmel; [FlyBase]
  • The gene innexin 2 is referred to in FlyBase by the symbol Dmel\inx2 (CG4590, FBgn0027108). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:6892696..6898182. It has the cytological map location 6E4. It is reported to have molecular function</span>: gap junction channel activity. There is experimental evidence that it is involved in the biological process</span>: morphogenesis of embryonic epithelium; olfactory behavior; foregut morphogenesis. 40 alleles are reported. The phenotypes of these alleles are annotated with: embryonic hindgut; embryonic salivary gland; embryonic head; embryonic segment; proventriculus primordium; embryonic Malpighian tubule; embryonic/larval proventriculus; embryonic epidermis; embryonic tracheal system; embryonic foregut. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
  • The gene innexin 2 is referred to in FlyBase by the symbol Dmel\inx2 (CG4590, FBgn0027108). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:6892696..6898182. It has the cytological map location 6E4. It is reported to have molecular function</span>: gap junction channel activity. There is experimental evidence that it is involved in the biological process</span>: morphogenesis of embryonic epithelium; olfactory behavior; foregut morphogenesis. 40 alleles are reported. The phenotypes of these alleles are annotated with: embryonic hindgut; embryonic salivary gland; embryonic head; embryonic segment; proventriculus primordium; embryonic Malpighian tubule; embryonic/larval proventriculus; embryonic epidermis; embryonic tracheal system; embryonic foregut. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
  • The gene innexin 2 is referred to in FlyBase by the symbol Dmel\inx2 (CG4590, FBgn0027108). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:6892696..6898182. It has the cytological map location 6E4. It is reported to have molecular function</span>: gap junction channel activity. There is experimental evidence that it is involved in the biological process</span>: morphogenesis of embryonic epithelium; olfactory behavior; foregut morphogenesis. 40 alleles are reported. The phenotypes of these alleles are annotated with: embryonic hindgut; embryonic salivary gland; embryonic head; embryonic segment; proventriculus primordium; embryonic Malpighian tubule; embryonic/larval proventriculus; embryonic epidermis; embryonic tracheal system; embryonic foregut. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 367 amino acids

    Gene Ontology:
    Cellular Component: gap junction [IDA][ISS][NAS]
    integral to membrane [NAS]
    Biological Process: foregut morphogenesis [IMP]
    morphogenesis of embryonic epithelium [IMP]
    olfactory behavior [IMP]
    Molecular Function: gap junction channel activity [NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFDVFGSVKG LLKIDQVCID NNVFRMHYKA TVIILIAFSL LVTSRQYIGD PIDCIVDEIP  60
   61 LGVMDTYCWI YSTFTVPERL TGITGRDVVQ PGVGSHVEGE DEVKYHKYYQ WVCFVLFFQA 120
  121 ILFYVPRYLW KSWEGGRLKM LVMDLNSPIV NDECKNDRKK ILVDYFIGNL NRHNFYAFRF 180
  181 FVCEALNFVN VIGQIYFVDF FLDGEFSTYG SDVLKFTELE PDERIDPMAR VFPKVTKCTF 240
  241 HKYGPSGSVQ THDGLCVLPL NIVNEKIYVF LWFWFIILSI MSGISLIYRI AVVAGPKLRH 300
  301 LLLRARSRLA ESEEVELVAN KCNIGDWFLL YQLGKNIDPL IYKEVISDLS REMSGDEHSA 360
  361 HKRPFDA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..169] MSA 8.11099 View MSA. No confident structure predictions are available.
    2 View Details [170..367] MSA 4.104996 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle