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Protein Overview: Atx-1-PB

General Information:
Name(s) found: Atx-1-PB / FBpp0289092 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • The gene Ataxin 1 is referred to in FlyBase by the symbol Dmel\Atx-1 (CG4547, FBgn0029907). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:6715052..6718238. It has the cytological map location 6D3. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: binding. There is experimental evidence that it is involved in the biological process</span>: photoreceptor cell maintenance; imaginal disc-derived wing vein specification. 5 alleles are reported. The phenotypes of these alleles are annotated with: eye; interommatidial bristle; wing margin bristle; metathoracic bristle; eye photoreceptor cell; wing; ommatidium; mesothoracic bristle. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 230 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: photoreceptor cell maintenance [IMP]
    imaginal disc-derived wing vein specification [IMP]
    Molecular Function: binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQMHMELSYG RGYDPIGRQP PSLPPPSQQH WSSNGFSDDS ASCFRRGSYI ELASGAMRRV  60
   61 EDIRTEDFIQ SALRSQLFEL REATVVRIDW SGCPSLVTLT FSYDTHHAKM DLQVQPGHPM 120
  121 FVYGQGWASC DPQLSLQLYE LKCQQLQVGD ICLSLVPNEQ PAAPCPPQPA PPPPCPPPSL 180
  181 PPSMEMPVPM GSPPTGSYGF LPFKHPYEMY AQMASFVAVY TQHMMGKLNY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..230] PSI-BLAST 51.39794 AXH domain of human spinocerebellar ataxin-1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  0.707059204953393 bayes_pls_golite062009
  • protein binding
    		•  0.079651215445451 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

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