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Protein Overview: APC7-PB

General Information:
Name(s) found: APC7-PB / FBpp0070908 [FlyBase]
Description(s) found:
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  • gi|24640160|ref|NP_727101.1| anaphase promoting complex 7, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|22831829|gb|AAN09176.1| anaphase promoting complex 7, isoform B [Drosophila melanogaster] [NCBI NR]
  • The gene Anaphase Promoting Complex 7 is referred to in FlyBase by the symbol Dmel\APC7 (CG14444, FBgn0029879). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:6491078..6493733. It has the cytological map location 6C1. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: binding. There is experimental evidence that it is involved in the biological process</span>: mitosis. 4 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • >CG14444-PB translation from_gene[CG14444 CG14444 FBgn0029879] seq_release:3 mol_weight=60001 cds_boundaries:(X:6,337,801..6,339,684[+]) aa_length:528 transcript_info:[CG14444-RB seq_release:3] gene_info:[gene symbol:CG14444 FBgn0029879 gene_boundaries [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q8IRQ6) CG14444-PB [DrosMelano7227.FASTAC.txt]
  • CG14444-PB, isoform B [Drosophila melanogaster]gi|24640160|ref|NP_727101.1| CG14444-PB [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=X:join(6491458..6491806,6491967..6492637,6492708..6492988,6493059..6493344); ID=FBpp0070908; name=APC7-PB; parent=FBgn0029879,FBtr0070947; dbxref=FlyBase:FBpp0070908,FlyBase_Annotation_IDs:CG14444-PB,GB_protein:AAN09176.1,REFSEQ:NP_72710 [fly-100309-contam.fasta]
  • Anaphase Promoting Complex 7 CG14444-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG14444-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=X:join(6491458..6491806,6491967..6492637,6492708..6492988,6493059..6493344); ID=FBpp0070908; name=APC7-PB; parent=FBgn0029879,FBtr0070947; dbxref=FlyBase:FBpp0070908,FlyBase_Annotation_IDs:CG14444-PB,GB_protein:AAN09176.1,REFSEQ:NP_727101,GB_protein:AAN09176; MD5=af3f09a2548d86313480be39ead95c9e; length=528; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=X:join(6491458..6491806,6491967..6492637,6492708..6492988,6493059..6493344); ID=FBpp0070908; name=APC7-PB; parent=FBgn0029879,FBtr0070947; dbxref=FlyBase:FBpp0070908,FlyBase_Annotation_IDs:CG14444-PB,GB_protein:AAN09176.1,REFSEQ:NP_727101,GB_protein:AAN09176; MD5=af3f09a2548d86313480be39ead95c9e; length=528; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • Anaphase promoting complex 7, isoform B OS=Drosophila melanogaster GN=Apc7 PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=X:join(6491458..6491806,6491967..6492637,6492708..6492988,6493059..6493344); ID=FBpp0070908; name=Apc7-PB; parent=FBgn0029879,FBtr0070947; dbxref=FlyBase:FBpp0070908,FlyBase_Annotation_IDs:CG14444-PB,GB_protein:AAN09176.1,REFSEQ:NP_727101,GB_protein:AAN09176,FlyMine:FBpp0070908,modMine:FBpp0070908; MD5=af3f09a2548d86313480be39ead95c9e; length=528; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=X:join(6597425..6597773,6597934..6598604,6598675..6598955,6599026..6599311); ID=FBpp0070908; name=APC7-PB; parent=FBgn0029879,FBtr0070947; dbxref=FlyBase:FBpp0070908,FlyBase_Annotation_IDs:CG14444-PB,GB_protein:AAN09176.1,REFSEQ:NP_727101,GB_protein:AAN09176,FlyMine:FBpp0070908,modMine:FBpp0070908; MD5=af3f09a2548d86313480be39ead95c9e; length=528; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=X:join(6597425..6597773,6597934..6598604,6598675..6598955,6599026..6599311); ID=FBpp0070908; name=APC7-PB; parent=FBgn0029879,FBtr0070947; dbxref=FlyBase:FBpp0070908,FlyBase_Annotation_IDs:CG14444-PB,GB_protein:AAN09176.1,REFSEQ:NP_727101,GB_protein:AAN09176,FlyMine:FBpp0070908,modMine:FBpp0070908; MD5=af3f09a2548d86313480be39ead95c9e; length=528; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Isoform of Q9W3Y6, Anaphase promoting complex subunit 7, isoform B OS=Drosophila melanogaster GN=APC7 PE=4 SV=1 [DROME.fasta.20160308]
  • FBpp0070908 type=protein; loc=X:join(6597425..6597773,6597934..6598604,6598675..6598955,6599026..6599311); ID=FBpp0070908; name=APC7-PB; parent=FBgn0029879,FBtr0070947; dbxref=FlyBase:FBpp0070908,FlyBase_Annotation_IDs:CG14444-PB,GB_protein:AAN09176.1,REFSEQ:NP_727101,GB_protein:AAN09176,FlyMine:FBpp0070908,modMine:FBpp0070908; MD5=af3f09a2548d86313480be39ead95c9e; length=528; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=X:join(6597425..6597773,6597934..6598604,6598675..6598955,6599026..6599311); ID=FBpp0070908; name=APC7-PB; parent=FBgn0029879,FBtr0070947; dbxref=FlyBase:FBpp0070908,FlyBase_Annotation_IDs:CG14444-PB,GB_protein:AAN09176.1,REFSEQ:NP_727101,GB_protein:AAN09176,UniProt/TrEMBL:Q8IRQ6,FlyMine:FBpp0070908,modMine:FBpp0070908; MD5=af3f09a2548d86313480be39ead95c9e; length=528; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 528 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: mitosis [IMP]
    Molecular Function: binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMRHKNAVLV AIESSYPEFG DAEQRRRAAE CYRQIGNTDM AIETLLQVPP TLRSPRINLM  60
   61 LARLQHHGSR HGTTKKSEAV LAYKEVIREC PMALQVIEAL LELGVNGNEI NSLVMHAATV 120
  121 PDHFDWLSKW IKALAQMFNF KHSDASQTFL MLHDNTTLRC NEHLMMALGK CLYYNGDYFQ 180
  181 AEDIFSSTLC ANPDNVEAIG LMAVLCGQEG GCEQDSADMD YLFAKVSSEV KYTASHWFAH 240
  241 AQLLYDEGKF ERGLNFVEKC LDSEPRNHEA LILRGRLLIA LERHTQAVCA FRTAQMVAPY 300
  301 RFEIYRGLFH SYLAQKRFKE ANALCNWTIR LFQNSPRSFT MFGRTLFLFP DPRMRRTARK 360
  361 FAEKSLKINH IYTPAVNLIA DICQVEGPTK AIIKLLEKHV IIFPKVNLLN HLGDIMRKQK 420
  421 EPVKAMEYYY KALRQDPKSK RTLRGLRLLA KSDDESPVLD ESDDIGMDNQ QSINDLTTLC 480
  481 EATNAQGAEG AESVENSREA SSSAAARSGQ EEDVDEHDWI DVPDGMSY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..453] PSI-BLAST 59.0 The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.
    2 View Details [454..528] PSI-BLAST 21.69897 No description for 2j9qA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.23224150119114 bayes_pls_golite062009
  • protein binding
    		•  1.11681353322487 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.80

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle