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Protein Overview: GlcAT-I-PA

General Information:
Name(s) found: GlcAT-I-PA / FBpp0070612 [FlyBase]
Description(s) found:
Found 22 descriptions.
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  • The gene GlcAT-I is referred to in FlyBase by the symbol Dmel\GlcAT-I (CG32775, FBgn0066114). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:4025250..4026866. It has the cytological map location 4B1. There is experimental evidence that it has the molecular function</span>: galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity. It is reported to be involved in the biological process</span>: proteoglycan biosynthetic process. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 306 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEA]
    plasma membrane [ISS]
    Biological Process: proteoglycan biosynthetic process [NAS]
    Molecular Function: glucuronosyltransferase activity [ISS]
    galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity [IDA][ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEVRIRPRQ VLILIIVFLV VLMMVHRNGK RTCQGPEYLQ AMFVQGDTLP TIYAVTPTYP  60
   61 RPAQKAELTR LSHLFMLLPH LHWIIVEDTN ATTPLVRNLL DRAGLEKRST LLNIKTPSEF 120
  121 KLKGKDPNWI KPRGVEQRNL ALAWLRNHVD VDRHSIVFFM DDDNSYSTEL FAEMSKIERG 180
  181 RVGVWPVGLV GGLMVERPLL TEDGTKVTGF NAAWRPERPF PIDMAAFAIS MDLFIRNPQA 240
  241 TFSYEVQRGY QESEILRHLT TRDQLQPLAN RCTDVLVWHT RTEKTKLAAE EALLKKGQRS 300
  301 DGGMEV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..306] PSI-BLAST 100.0 1,3-Glucuronyltransferase I (glcAT-I)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • glucuronosyltransferase activity
    		•  3.35834119860565 bayes_pls_golite062009
  • transferase activity, transferring hexosyl groups
    		•  2.25735925472076 bayes_pls_golite062009
  • catalytic activity
    		•  1.88676710996045 bayes_pls_golite062009
  • UDP-glycosyltransferase activity
    		•  1.78834682378184 bayes_pls_golite062009
  • transferase activity
    		•  1.47184463413038 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.917132255588883 bayes_pls_golite062009
  • transferase activity, transferring glycosyl groups
    		•  0.897978517422275 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  0.83784639848251 bayes_pls_golite062009
  • N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity
    		•  0.827245112325815 bayes_pls_golite062009
  • acetylgalactosaminyltransferase activity
    		•  0.767787396530785 bayes_pls_golite062009
  • heparan sulfate N-acetylglucosaminyltransferase activity
    		•  0.76690934595784 bayes_pls_golite062009
  • UDP-N-acetylglucosamine diphosphorylase activity
    		•  0.513376694534047 bayes_pls_golite062009
  • polypeptide N-acetylgalactosaminyltransferase activity
    		•  0.490017972387603 bayes_pls_golite062009
  • mannosyltransferase activity
    		•  0.357617709239079 bayes_pls_golite062009
  • uridylyltransferase activity
    		•  0.321928989676507 bayes_pls_golite062009
  • mannose-phosphate guanylyltransferase activity
    		•  0.2363835251362 bayes_pls_golite062009
  • cytidylyltransferase activity
    		•  0.218759888732981 bayes_pls_golite062009
  • guanylyltransferase activity
    		•  0.0539392112504681 bayes_pls_golite062009
  • glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity
    		•  0.0254320217142603 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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