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Protein Overview: lva-PC, FBpp0309608

General Information:
Name(s) found: FBpp0309608 [FlyBase]
lva-PC / FBpp0070596 [FlyBase]
Description(s) found:
Found 27 descriptions.
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  • type=protein; loc=X:complement(3849908..3850005,3850082..3850278,3850340..3850460,3850546..3854443,3854510..3854617,3854675..3858385,3858450..3858530,3858600..3858671,3858734..3858787); ID=FBpp0309608; name=lva-PD; parent=FBgn0029688,FBtr0342740; dbxref=FlyBase:FBpp0309608,FlyBase_Annotation_IDs:CG6450-PD; MD5=6396e4c3e2e9c0dc879860b8ca19f160; length=2779; release=r5.56; species=Dmel; [FlyBase]
  • The gene lava lamp is referred to in FlyBase by the symbol Dmel\lva (CG6450, FBgn0029688). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:3849578..3858787. It has the cytological map location 4A1. There is experimental evidence that it has the molecular function</span>: actin binding; protein binding; microtubule binding. There is experimental evidence that it is involved in the biological process</span>: negative regulation of dendrite morphogenesis; establishment of Golgi localization; cellularization. 8 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 2779 amino acids

    Gene Ontology:
    Cellular Component: cell cortex [IDA]
    Golgi apparatus [IDA][NAS][TAS]
    Biological Process: negative regulation of dendrite morphogenesis [IMP]
    establishment of Golgi localization [IMP]
    cellularization [IMP][NAS][TAS]
    Molecular Function: protein binding [IPI]
    actin binding [IDA]
    spectrin binding [TAS]
    microtubule binding [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEDSGALES SYDFSIVQPD DHEYGEADIR LAGSSNDLSS LQNVSASTTR GTKGKGRLDS  60
   61 LKENLYKQQE RLTALKERAL RKSQDERHKS SMSDSMESLK TLGQKLTVLK TRSGDSSTPL 120
  121 VSPTKDSDPG DVSLLQTSGS EKLLMLTQRT EQNRALLEQR KRDLAKSLLS VKSNIGHQTT 180
  181 AELGSSMTDL RHAASVSNPP VSRHRSALDL EAQGQEAVDE SRVKLLRSRM KLTELKQGRQ 240
  241 EQELNELRTE LAKRAKLIER LELSGAELQR TLTQRNEELE QLRVVQAEED SLKVQENSRL 300
  301 QGEVLVLRER LAELENVNDL LETTRCELQE ELTTARERQR NLELEQEQEK ASRSPQSEAA 360
  361 HTDAQVSAEL AKQLQELTNQ LADLQATNEE LRQQVAAQAK LQVTDEIVSQ RLEELEATIA 420
  421 AQLLELQEQK SAMAAQNEEL AEKTTELNVL NVNLRLLEEK LAQSSRSKPL FLEDHSEDSA 480
  481 ASKQMQEDLQ QLKLKLDETN KANIKLKLKC KQAEKKLQKF QSQDGQQQLA SLLADNEELQ 540
  541 QRIAVLEDEK GQWQLANMQE DDRQPEQSTE SNNPLQLETI RLLEEQKLEL QQALEALLSS 600
  601 SSSAESIEIV ERHHLECLGQ RRPASEGDAQ EQKQVHPPGP SHVSELTQTE QTEEEDSSGE 660
  661 TLSQLRERLE LFTQERGEVL DKLEQLSAEN LQLQARLEES SSSLQLLQRE REKDLISSTS 720
  721 TSSNLSQELS SMQRSSEVVA TLDAGEGGPV LFEKCEKSLS KLNSELEAYR KANDRQAKFN 780
  781 VSKKLAKEAK NCHTQLSELL HKVKEASTAV ETVTVVETVV AVTAPNGKAL AEYEQLNAQN 840
  841 AELKAVISRL RQELDELRES YPETEAPLAI VGSDSQREDE ILQLQSQLED ARSLQAEQRQ 900
  901 QIEEQVDQIK ELRQTEAEQL QLVARQSAEI TQLQLQSEQF DQLLNSKEMS HEKQLEQQTR 960
  961 IRRELEARAE SLEGELSILQ TLVAEQKQQL IESVSESEHA LNLKMLELQS AQEELRELRA1020
 1021 KEDPDQLREA LRVSKSLVAQ QVRELTSSQE TVDALNQQIQ EYQGLEHAHK EEQFKNRELR1080
 1081 EKLKKYALNL KKRTQDNADL EQKVQELTSQ LQEQQELVKQ KEEVEREPIV DNHRVEQLQQ1140
 1141 QVSKLNEDLK AKIHLNLENR DALRQLKQQI QEQEQLIQER DAELQDANLV SKELRRERQE1200
 1201 ADQEVFQLGQ ENSRLREEIS KLQEEIHNLG QRVNEEPTAV EDLRRQLEAK SKKFEKSKEL1260
 1261 IKLRNATIQS LQRELQQLQQ DQDSEVEHVR NARAAHEQLR LEKDAEITAL RQEILKLERS1320
 1321 RAAGEGDDTI TKTSHQLLES QSQQQAESLQ VAERELQQLR VQLTAAQEQH ALLAQQYASD1380
 1381 KANFEMTIAR LETLHEGIQA KLQEDASYIE SLEAQNTELQ ARSAALEEQA ASQANQQAAS1440
 1441 QDKVQILEQQ LKEQREQEEQ KRQQDQQLQE RFYELGQREQ AQSRQLELLT SEAEESRQQL1500
 1501 AGLRTEYESL LAKHSQLTAT AQAEREQMSS HSQEELAELR QQLDVKEADL HRQRQVYDAK1560
 1561 LAAKATELDE LECDLNSHVE RAAAETRELC QQLERSQELV AQRTEELQRL NEEFQEVERE1620
 1621 RSTLSREVTL LRLQHDSAEQ DVLELQELRM QAMQDKTEMD NLRTQIDALC ANHSQELQAL1680
 1681 QQRIAELDTL GQNQTDDQVY IETENKRLAE QLSELQAQLA RQQHQQQQQQ HHHPAVQSQQ1740
 1741 HPPPASLFFG GDALAAPSPF DEIAQPLRVS SLAASAPPPI SPPPTIEDLQ RNVSDLEKHA1800
 1801 QDLETKLLAR NQNLAEQEER RLQLEQRLSE VERLLSERTQ QLADIQTANE ERDRLAALEK1860
 1861 LIQPAAAPTL DMFFGGQAEE TVPDAVSHHL DLGLPQTEPV VEPLIQPKKA YLCQPKQEIQ1920
 1921 EQTAQTIDWG VDEDPWASAA NEAPQTDVEH LHTRIAQLEL QLSNAEQQKT ELQTKAAKLM1980
 1981 KRLKEYKTKA TTTATPTVTV DNDLDSTIIE ELKHQLQLQE SRLSKAEEIS QQHALEKEKL2040
 2041 AKRIDVLTAG NDRMAEMKER QDMDVQMYQA RIRELQEKLS QLDQWGEPAA TVSSSLDGDE2100
 2101 AARIESLQQE IQQLRQQVSE LEDERTRDQA ELGALRQSSQ GYDEAEDNQK LELQQLRQQE2160
 2161 SELEALRTRD QSELEALRQS CQGHDETVRI ATLQQDNQQL ELQQLRQAII ELETLRARDQ2220
 2221 TELEALRQSS QGHDEAARIA IEQRDNQQLE LQQLRQQLIE LEALRARDQA ELEALRQSCQ2280
 2281 GQQLSVDMAS RNDEQMAQLQ EKESEIVHLK QRIEELMRED QTEKLVFEIL TKNQELQLLR2340
 2341 MQVKQLEEDK EDQQVSAAPP KDDGETVEKL KSLCQQLQQE KSDMEEELRV LNNHVLSSLE2400
 2401 LEDRMKQTLL QLDTKNIEIT ELRRSLEILQ SQNLGQNSAA EQIPDLSAIN QQWEQLVEQK2460
 2461 CGEVASIWQE HLSQREAAFK AQLEEVTQQQ QRELPQSQQS TQGEATSDIM QKMQKALETQ2520
 2521 EMEIVTLKEQ LAIRSAEYAR LAAQYDPFRL QNRGGASGGN PASTTVSAGG PPSLTANEPL2580
 2581 PEYVLKADLD YALMMLHQRD MRVEEMIVEL VQLLEERDHL QLKLSDTLRQ LETERSRVSD2640
 2641 EPSATASSSA ASSSSPSKIS SAGSNSELLG TTSAAGSDLK QKLAELQTVK HSKDKVIVDE2700
 2701 REQRLQQMLQ LQKDMAKQGS GSQSGAGAVA AVAAPTSAAP TAIGVDLSQS GLRSPSMMLM2760
 2761 DWILGNNNKE EEAGHQTTG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.89

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle