Protein Overview: trol-PC

General Information:
Name(s) found:	trol-PC / FBpp0070438 [FlyBase]
Description(s) found: Found 13 descriptions. SHOW ALL	The gene terribly reduced optic lobes is referred to in FlyBase by the symbol Dmel\trol (CG33950, FBgn0261451). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:2365016..2439423. It has the cytological map location 3A1-3A4. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: maintenance of epithelial cell apical/basal polarity. 171 alleles are reported. The phenotypes of these alleles are annotated with: female reproductive system; eye; dorsal mesothoracic disc; neuroblast; brain; dorsal metathoracic disc; larval brain; larval optic lobe; thoracic neuroblast; larval central nervous system. It has 8 annotated transcripts and 8 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	4117 amino acids
Gene Ontology:
Cellular Component:	lipid particle [IDA] basement membrane [ISS] extracellular matrix [IEA] proteinaceous extracellular matrix [NAS]
Biological Process:	maintenance of epithelial cell apical/basal polarity [IMP] asymmetric neuroblast division [NAS] cell adhesion [IEA]
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSETPDPLT PSPQPPLAND SLNNALHQGV KAQRGWMRMW NVCIFMSFVL SCHFDVDCWQ  60
   61 CLHSRKSRAK NKCQANEFRC NNGDCIDARK RCNNVSDCSE GEDENEECPA ACSGMEYQCR 120
  121 DGTRCISVSQ QCDGHSDCSD GDDEEHCDGI VPKLRYTCPK GKFTCRDLSC ISIVHRCDGR 180
  181 ADCPNDRSDE EGCPCLYDKW QCDDGTCIAK ELLCNGNIDC PEDISDERYC EGGYDSEECR 240
  241 FDEFHCGTGE CIPMRQVCDN IYDCNDYSDE VNCVEGEEED RVGIPIGHQP WRPASKHDDW 300
  301 LHEMDTSEYQ VYQPSNVYEK ANSQNPCASN QFRCTTSNVC IPLHLRCDGF YHCNDMSDEK 360
  361 SCEQYQRHTT TRRPLTLATP TSRITTQGPG LLERRNTTTA TEASRWPWAT KTTTIATTTS 420
  421 NPITTVGVAN SPPQTCLENI EFACHNRDCI SIESVCDGIP DCGRNEDEDD ALCKCSGDKY 480
  481 KCQRGGGCIP KSQVCDGKPQ CHDRSDESAC HLHGRLNKTR LGVKCLESQY QCGDGSCISG 540
  541 YKRCNGIHDC ADASDEYNCI YDYEDTYDTD PNNNPLNECD ILEFECDYSQ CLPLEKKCDG 600
  601 YADCEDMSDE LECQSYTDHC LESEFECDSY CLPRDQLCNG IPNCQDGSDE RNCTFCREDA 660
  661 YLCNTGECVA DNQRCNGIAD CADGSDERHC ARIYCPPNKL ACNGTCVSRR IKCDGIRDCL 720
  721 DGYDEMYCPE TNNHYPTQNV NVIRPKLGPN PIPKSCRPHE WQCANLECID SSLQCNEIKD 780
  781 CSDGSDEELS VCFGTATTRL KPSDCSPEQF YCDESCYNRS VRCNGHVDCS DGSDEVGCSL 840
  841 PCPQHQCPSG RCYTESERCD RHRHCEDGSD EANCTAILCK DNEFLCFDRQ FCINATQQCD 900
  901 GYYDCRDFSD EQNCIGCYAN QFRCNNGDCV SGSAPCNGYS ECSDHSDELN CGGTQECLPN 960
  961 QFRCNSGQCV SSSVRCNGRT DCQDSSDEQN CGHRHTEVSQ GLETTGVFTT STTSTTAMTP1020
 1021 LRIICPPTSF KCENGPCISL GLKCNGRVDC PYDGSDEADC GQISNDIDPA DSNDRRPNQL1080
 1081 NLKTYPDSQI IKENNDVGSR PESACTEYQA TCMNGECIDK SSICDGNPDC SDASDEQSCS1140
 1141 LGLKCQPNQF MCSNSKCVDR TWRCDGENDC GDNSDETSCD PEPSGAPCRY NEFQCRSGHC1200
 1201 IPKSFQCDNV PDCTDGTDEV GCMAPLPIRP PPQSVSLLEY EVLELTCVAT GTPTPTIVWR1260
 1261 LNWGHVPDKC ESKSYGGTGT LRCPDMRPQD SGAYSCEIIN TRGTHFVNPD TIVTVRPVRT1320
 1321 DVCEAGFFNM LARKAEECVQ CFCFGVAKAC DSANLFTYAI HPPILSHRVV SVELSPLRQI1380
 1381 VINEAAPGQD LLTLLHGVQF RATNVHFSGR ETPYLALPAD YMGNQLKSYG GNLRYEVNYR1440
 1441 GSGRPVNGPD VIITGNRFTL TYRVRTQPGQ NNRVSIPFVP GGWQKPDGRK ASREEIMMIL1500
 1501 ANVDNILIRL GYLDSTAREV DLINIALDSA GTADKGLGSA SLVEKCQCPP GYVGDSCESC1560
 1561 ASGYVRQPGG PWLGHCVPFI PDSCPSGTYG DPRRGVPCKE CPCPLTGSNN FASGCQQSPD1620
 1621 GDVVCRCNEG YTGRRCEQCA AGYQGNPLAA GGICRRIPDT SCNVDGTYSV HSNGTCQCKD1680
 1681 SVIGEQCDTC KSKSFHLNSF TYTGCIECFC SGVGLDCDSS TWYRDQVTST FGRSRVDHGF1740
 1741 VLVTNYMQPT PDTVPVSMAA EPNALSFIGS ADQSGNTLYW SLPAAFLGNK LSSYGGKLTY1800
 1801 TLSYSPLPNG IMSRNSAPDV VIKSGEDLRL IHYRKSQVVP SVANTYSVEI KESAWQRGDE1860
 1861 VVANREHVLM ALSDITAIYI KATYTTSTKE ASLRQVTLDV ATPTNLGTPR AVEVEQCRCP1920
 1921 EGYLGLSCEQ CAPGYARDPE GGIYLGLCRP CECNGHSKYC NSDTGDCEEC SDNTEGPSCE1980
 1981 RCAAGYVGDA TRGTIYDCQP DEGYPIPSPP APGNQTLECT AYCQIEGIYD CRGNECLCKR2040
 2041 NVIGDQCDQC RPGTYGLSAQ NQDGCKECYC SGLASQCRSA ALYRQLIPVD FILNAPLITD2100
 2101 ESGAVQDTEN LIPDISRNMY TYTHTSYLPK YWSLRGSVLG NQLFSYGGRL SYSLIVESYG2160
 2161 NYERGHDIVL IGNGLKLIWS RPDGNENQEE YNVRLHEDEQ WTRQDRESAR PASRSDFMTV2220
 2221 LSDLQHILIR ATPRVPTQST SIGNVILESA VTTRTPGATH ASDIELCQCP SGYVGTSCES2280
 2281 CAPLHYRDAS GSCSLCPCDV SNTESCDLVS GGYVECRCKA RWKGDRCREI DTNDPTDIGT2340
 2341 EDPVLTQIIV SIQKPEITIV PVGGSMTLSC SGRMRWSNSP VIVNWYKENS RLPENVEVQG2400
 2401 GNLYLYDLQV SDSGVYICQA VNNETASVFK DTVSITITKK DQLSPAEIVN LPSHVTFEEY2460
 2461 VNNEIICEVL GNPAPRVTWA RVDGHADAQS TRTYDNRLIF DSPRKSDEGR YRCQAENDQN2520
 2521 RDEKYVIVYV QSNPPQPPPQ QDRLYITPEE INGLAGESFQ LNCQFTSVAS LRYDWSHNGR2580
 2581 SLSSSPARNV EIRGNTLEVR DASESDSGVY TCVAYDVRTR RNFTESARVN IDRREEQPFG2640
 2641 NKPIIESLEQ NILIIQGEDY SITCEASGSP YPSIKWAKVH DFMPENVHIS GNVLTIYGAR2700
 2701 FENRGVYSCV AENDHGSDLS STSIDIEPRE RPSVKIVSAP LQTFSVGAPA SLYCTVEGIP2760
 2761 DPTVEWVRVD GQPLSPRHKI QSPGYMVIDD IQLEDSGDYE CRAKNIVGEA TGVATITVQE2820
 2821 PTLVQIIPDN RDLRLTEGDE LSLTCVGSGV PNPEVEWVNE MALKRDLYSP PSNTAILKIY2880
 2881 RVTKADAGIY TCHGKNEAGS DEAHVRVEVQ ERRGDIGGVD DDSDRDPINY NPPQQQNPGI2940
 2941 HQPGSNQLLA TDIGDNVTLT CDMFQPLNTR WERVDGAPLP RNAYTIKNRL EIVRVEQQNL3000
 3001 GQYRCNGIGR DGNVKTYFVK ELVLMPLPRI RFYPNIPLTV EAGQNLDVHC QVENVRPEDV3060
 3061 HWSTDNNRPL PSSVRIVGSV LRFVSITQAA AGEYRCSAFN QYGNRSQIAR VAVKKPADFH3120
 3121 QVPQSQLQRH REGENIQLQC TVTDQYGVRA QDNVEFNWFR DDRRPLPNNA RTDSQILVLT3180
 3181 NLRPEDAGRY ICNSYDVDRG QQLPEVSIDL QVLTATPPPN SPIYLPPQLP AKSRDYSLKL3240
 3241 DDQSSNLRAG ESTDVECYSS DDTYTDVVWE RSDGAPLSNN VRQVGNRLVI SNVSPSDAGN3300
 3301 YVCKCKTDEG DLYTTSYKLE VEDQPHELKS SKIVYAKVGA NADLQCGADE SRQPTYRWSR3360
 3361 QYGQLQAGRS LMNEKLSLDS VQANDAGTYI CTAQYADGET ADFPNILVVT GAIPQFRQEP3420
 3421 RSYMSFPTLP NSSFKFNFEL TFRPENGDGL LLFNGQTRGS GDYIALSLKD RYAEFRFDFG3480
 3481 GKPMLVRAEE PLALNEWHTV RVSRFKRDGY IQVDEQHPVA FPTLQQIPQL DLIEDLYIGG3540
 3541 VPNWELLPAD AVSQQVGFVG CISRLTLQGR TVELIREAKY KEGITDCRPC AQGPCQNKGV3600
 3601 CLESQTEQAY TCICQPGWTG RDCAIEGTQC TPGVCGAGRC ENTENDMECL CPLNRSGDRC3660
 3661 QYNEILNEHS LNFKGNSFAA YGTPKVTKVN ITLSVRPASL EDSVILYTAE STLPSGDYLA3720
 3721 LVLRGGHAEL LINTAARLDP VVVRSAEPLP LNRWTRIEIR RRLGEGILRV GDGPERKAKA3780
 3781 PGSDRILSLK THLYVGGYDR STVKVNRDVN ITKGFDGCIS RLYNFQKPVN LLADIKDAAN3840
 3841 IQSCGETNMI GGDEDSDNEP PVPPPTPDVH ENELQPYAMA PCASDPCENG GSCSEQEDVA3900
 3901 VCSCPFGFSG KHCQEHLQLG FNASFRGDGY VELNRSHFQP ALEQSYTSMG IVFTTNKPNG3960
 3961 LLFWWGQEAG EEYTGQDFIA AAVVDGYVEY SMRLDGEEAV IRNSDIRVDN GERHIVIAKR4020
 4021 DENTAILEVD RMLHSGETRP TSKKSMKLPG NVFVGGAPDL EVFTGFRYKH NLNGCIVVVE4080
 4081 GETVGQINLS SAAVNGVNAN VCPANDDPLG GTEPPVV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.58

Protein Overview: trol-PC

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: