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Protein Overview: FBpp0309599, FBp...

General Information:
Name(s) found: FBpp0309599 [FlyBase]
FBpp0301966 [FlyBase]
FBpp0301965 [FlyBase]
DAAM-PB / FBpp0070229 [FlyBase]
Description(s) found:
Found 36 descriptions.
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  • type=protein; loc=X:complement(1184479..1185377,1185438..1185601,1185659..1185820,1185877..1186019,1186085..1186290,1186354..1187049,1187113..1187290,1187351..1188319,1189043..1189087); ID=FBpp0309599; name=DAAM-PG; parent=FBgn0025641,FBtr0342731; dbxref=FlyBase:FBpp0309599,FlyBase_Annotation_IDs:CG14622-PG; MD5=3a175b23dbc22f0ba50f32d44af96881; length=1153; release=r5.56; species=Dmel; [FlyBase]
  • type=protein; loc=X:complement(1184479..1185377,1185438..1185601,1185659..1185820,1185877..1186019,1186085..1186290,1186354..1187049,1187113..1187290,1187351..1188319,1189043..1189087); ID=FBpp0301966; name=DAAM-PF; parent=FBgn0025641,FBtr0310283; dbxref=REFSEQ:NP_726723,GB_protein:AAF45601,FlyBase:FBpp0301966,FlyBase_Annotation_IDs:CG14622-PF; MD5=3a175b23dbc22f0ba50f32d44af96881; length=1153; release=r5.56; species=Dmel; [FlyBase]
  • type=protein; loc=X:complement(1184479..1185377,1185438..1185601,1185659..1185820,1185877..1186019,1186085..1186290,1186354..1187049,1187113..1187290,1187351..1188319,1189043..1189087); ID=FBpp0301965; name=DAAM-PE; parent=FBgn0025641,FBtr0310282; dbxref=REFSEQ:NP_001259126,GB_protein:AGB94972,FlyBase:FBpp0301965,FlyBase_Annotation_IDs:CG14622-PE; MD5=3a175b23dbc22f0ba50f32d44af96881; length=1153; release=r5.56; species=Dmel; [FlyBase]
  • The gene Dishevelled Associated Activator of Morphogenesis is referred to in FlyBase by the symbol Dmel\DAAM (CG14622, FBgn0025641). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:1183740..1216389. It has the cytological map location 1F2-1F3. Based on sequence similarity, it is predicted to have molecular function</span>: actin binding. There is experimental evidence that it is involved in the biological process</span>: actin filament bundle formation; regulation of tube architecture, open tracheal system; open tracheal system development. 18 alleles are reported. The phenotypes of these alleles are annotated with: taenidial fold; filamentous actin; larval trachea; larval cuticle; larval tracheal system. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1153 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: regulation of tube architecture, open tracheal system [IMP]
    actin cytoskeleton organization [NAS]
    cuticle pattern formation [NAS]
    actin filament bundle assembly [IMP]
    open tracheal system development [IMP]
    Molecular Function: actin binding [IEA][ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPGFRGRRVW CGCFKDDEPP EICVVEGAFT LQTLTPTQPM PSVDELDTKF AELVEELDLT  60
   61 APNKEAMLSL PAQKKWQIYC SRKLPLDAAD GPDAAAVTQP PTAEHYIERL KELVVHISLS 120
  121 PEDSPSHELG NRLDGHAAFV DALKTALRTS THSFVLRFVE LDGLPALLDL LLQLDIRVAN 180
  181 SPLHTSLIGC IKALMNNSMG RAHVLAHPTA IDTIARSLAA DNIRTKIAAL EILGAVCLVP 240
  241 GGHRKVLQAM LHFQVFATER TRFQSIVNDL DRSTYAYRDN VNLKTALMSF VNAVLNYGPG 300
  301 QENLEFRLHL RYEFLMLGIQ PVIDKLRTHE NETLDRHLDF FEMVRAEDEK EFARRFKEEH 360
  361 VDTKSAGSMF ELLRRKLSHS PAYPHMLSLL QHMLLLPYTG HCTEHWLLID RVVQQIVLQV 420
  421 EQRPNSDLIV DPDDPEKQLK LAAESPVHDP DVAPLQIDVA KLVRLLVKEE QLTQARKRAD 480
  481 ELERENFDVQ SRLAKKEQEL DLRMQEKEDL ETGLARMRER LEKESAQHSQ AVQRAQTAEM 540
  541 RAEDLQHRLI SEQQERARLE RLVTEGSIPD DQKVAGLTGC NGAVSPPPAP PMLKAIPPPP 600
  601 PPMAPSMMPP PPPPCPGAPP PPPSMAQTMA PAPPKVDLPK KNVPQPTNPL KSFNWSKLPD 660
  661 AKLQGTVWSE LDESKLYNNM ELESIDKLFS AYQKNGVSAT DGSYEDLRVT GKAAKQKVLS 720
  721 VIDGRRAQNC TILLSKLKMS DMEISKAILS MDSNEQLQLD MVEQLLKFTP SAEERALLDE 780
  781 HSEDIESLAR ADRFLYEISK IPHYEQRLKS LHYKKRFMLT INDLVPRITS VMEASREVAR 840
  841 SRRLRKLLEL VLALGNYMNR GARGNASGFR LASLNRLADT KSSAAKGTTL LHYLVQVIER 900
  901 KFKDLLKLED DIPHVREASK VSLGEMDKDI QMLRTGLADV AREIEFHRSS GPAQQGDRFL 960
  961 PVMREFHAQA SVRFAELEDK FQDMKTRFDR AVRLFGEDGS VLQPDEFFGI FDSFLAAFAE1020
 1021 ARHDNESFRR RQEEEEKRAK QEAELKKRTI ERKNKTGLMT SVARNLGLKS GSSNGDPDSP1080
 1081 AKGGDNKGEF DDLISALRTG DVFGEDMAKF KRSRKARVLN GGGSSTGHTS PPRHGSLQRE1140
 1141 ESGRERERTV RRQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..447] PSI-BLAST 60.69897 Crystal structure of mDIA1 GBD-FH3 in complex with RhoC-GMPPNP
    2 View Details [448..572] PSI-BLAST 48.69897 Crystal structure of the dimeric regulatory domain of mouse diaphaneous-related formin (DRF), mDia1
    3 View Details [573..623] deduced N/A No confident structure predictions are available.
    4 View Details [624..1153] PSI-BLAST 78.0 No description for 2j1dG was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.52869107451293 bayes_pls_golite062009
  • protein binding
    		•  0.91858015757355 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle