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Protein Overview: mav-PA

General Information:
Name(s) found: mav-PA / FBpp0088172 [FlyBase]
Description(s) found:
Found 22 descriptions.
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  • The gene maverick is referred to in FlyBase by the symbol Dmel\mav (CG1901, FBgn0039914). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 4:643842..646656. It has the cytological map location 102D1. Based on sequence similarity, it is predicted to have molecular function</span>: transforming growth factor beta receptor binding. Based on sequence similarity, it is predicted to be involved in the biological process</span>: transforming growth factor beta receptor signaling pathway. 3 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 701 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: transforming growth factor beta receptor signaling pathway [ISS]
    growth [IEA]
    Molecular Function: growth factor activity [IEA]
    transforming growth factor beta receptor binding [ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIIDINPNLT PKKETAVWCD SFQHKCKVSN RTIKIFPSLL NKSNWIVSIL WHICVHHTIT  60
   61 IRNSKAREPP CKHPPITDNA EAKLTLVCSR SLKLYKIWFI LILLMSTQHQ VSGHGIFRQT 120
  121 SSSKAVFSYY QPKENITFTN LQLQNLENEA KRLETNQHPI IRAKSTPKMG LKNVFESFSK 180
  181 QSRDSIYNAS SNKYSLINVS QSKNFPQLFN KKLSVQWINT VPIQSRQTRE TRDIGLETKR 240
  241 HSKPSKRVDE TRLKHLVLKG LGIKKLPDMR KVNISQAEYS SKYIEYLSRL RSNQEKGNSY 300
  301 FNNFMGASFT RDLHFLSITT NGFNDISNKR LRHRRSLKKI NRLNQNPKKH QNYGDLLRGE 360
  361 QDTMNILLHF PLTNAQDANF HHDKIDEANV RLMLLYSSSL ATNFRRGPGS RKNKISQISG 420
  421 NDNIERHCNF GDVNLNQSNK NSSQQLTLKV YQLLSANRRR KITSRKIEFG NVGFQETRTQ 480
  481 WIEFDVTKAV RSWLNKSHEN LGIEIQCDKC KSIGARILSD FSPSTPPRST ASSDEHLNLM 540
  541 PVLNIIGHGT LNSQQHGDAD IHQIMLTNNR SDQYVHHRSN HDSTWRKDKW TNNCYKLHQR 600
  601 CCRNQLDVAF KSIKGFEFIL QPKVFDAGYC HGRCPPRHNP AHHHALLQSL IWQEDHKRAP 660
  661 RPCCTPSKLE MLEILHVDEN HSDKLKISTW SDMQVVECAC S

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..75] deduced N/A No confident structure predictions are available.
    2 View Details [76..294] deduced N/A No confident structure predictions are available.
    3 View Details [295..388] MSA 1.238995 View MSA. No confident structure predictions are available.
    4 View Details [389..525] MSA 8.369992 View MSA. No confident structure predictions are available.
    5 View Details [526..701] PSI-BLAST 36.221849 BONE MORPHOGENETIC PROTEIN-7

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5
    Term Confidence Notes
  • receptor serine/threonine kinase binding
    		•  2.59151978891498 bayes_pls_golite062009
  • transforming growth factor beta receptor binding
    		•  2.37742979972948 bayes_pls_golite062009
  • transmembrane receptor protein serine/threonine kinase binding
    		•  2.37742979972948 bayes_pls_golite062009
  • receptor binding
    		•  2.35731964024213 bayes_pls_golite062009
  • binding
    		•  1.94128368349087 bayes_pls_golite062009
  • protein binding
    		•  1.64946640536226 bayes_pls_golite062009
  • growth factor activity
    		•  1.46380647398443 bayes_pls_golite062009
  • growth factor binding
    		•  0.115424337995679 bayes_pls_golite062009
  • vascular endothelial growth factor receptor binding
    		•  0.0947383314256207 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.47

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle