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Protein Overview: ferrochelatase-PA

General Information:
Name(s) found: ferrochelatase-PA / FBpp0085208 [FlyBase]
Description(s) found:
Found 23 descriptions.
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  • The gene ferrochelatase is referred to in FlyBase by the symbol Dmel\ferrochelatase (CG2098, FBgn0024891). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:27636176..27637985. It has the cytological map location 100D2. There is experimental evidence that it has the molecular function</span>: ferrochelatase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: protoporphyrinogen IX biosynthetic process. 5 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 384 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial inner membrane [ISS][NAS]
    Biological Process: protoporphyrinogen IX biosynthetic process [ISS][NAS]
    Molecular Function: ferrochelatase activity [IDA][ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFLHNTKFCR LASGLAGGVR NLSGQKPKTA ILMLNMGGPT HTDQVHDYLL RIMTDRDMIQ  60
   61 LPVQSRLGPW IAQRRTPEVQ KKYKEIGGGS PILKWTELQG QLMCEQLDRI SPETAPHKHY 120
  121 VGFRYVNPLT ENTLAEIEKD KPERVVLFSQ YPQYSCATSG SSFNSIFTHY RSNNLPSDIK 180
  181 WSIIDRWGTH PLLIKTFAQR IRDELAKFVE TKRNDVVILF TAHSLPLKAV NRGDAYPSEI 240
  241 GASVHMVMQE LGQTNPYSLA WQSKVGPLPW LAPATDDAIK GYVKQGLKNF ILVPIAFVNE 300
  301 HIETLHELDI EYCDELAKEV GVEEIRRAAT PNDHPLFIDA LTNVVADHLK SQQAVNPKFL 360
  361 MRCPMCSNPK CRESKSWYRQ LCSN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..384] PSI-BLAST 108.0 No description for 2po7A was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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