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Protein Overview: lox-PA

General Information:
Name(s) found: lox-PA / FBpp0085171 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • The gene lysyl oxidase-like is referred to in FlyBase by the symbol Dmel\lox (CG11335, FBgn0039848). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:27284102..27285591. It has the cytological map location 100C4. There is experimental evidence that it has the molecular function</span>: copper ion binding; protein-lysine 6-oxidase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: cell adhesion; protein modification process. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 360 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEA]
    Biological Process: protein modification process [ISS]
    oxidation reduction [IEA]
    cell adhesion [ISS]
    Molecular Function: copper ion binding [IDA]
    scavenger receptor activity [IEA]
    protein-lysine 6-oxidase activity [IDA][ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASFRFQLLQ LLVVLSQGWA NLNVQNNYRN MMVRLATNKA ALAGIQVLRE GRVEVSFDFG  60
   61 ASWGTICSTS WSMREANVVC RQLGLGYASK ASQGTEHGDS RKYPWGMVGT LCRGTERRLA 120
  121 DCIRESHYPN LCNARNHNVS IAACVSHSAD LEIGLVDIER TARLEAVPMS RLTCAMEEHC 180
  181 VSADAYEIRR TNPHAARILL RFSVKASNVG TADVSPYANY KEWVWHQCHR HYHSMNVFAT 240
  241 FDVYDLNYRK VAQGHKASFC LMDSECRPGV RQKYTCGNTT QGISVGCADT YTDVLDCQWV 300
  301 DVTRVPINRR YILRVALNPE YKLGEISFEN NGAECLLDYT GVRQTTRIFN CRRKPLWFKI 360
  361

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..147] PSI-BLAST 29.69897 STRUCTURE OF M2BP SCAVENGER RECEPTOR CYSTEINE-RICH DOMAIN
    2 View Details [148..237] PSI-BLAST 3.30103 No description for 2ja4A was found.
    3 View Details [238..360] FFAS03 1.1 No description for 2iwtB was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein binding
    		•  0.552410974340988 bayes_pls_golite062009
  • binding
    		•  0.536923542644072 bayes_pls_golite062009
  • catalytic activity
    		•  0.43947186099223 bayes_pls_golite062009
  • receptor activity
    		•  0.0495857193797902 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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