Protein Overview: tmod-PL, tmod-PE...

General Information:
Name(s) found:	tmod-PL / FBpp0291757 [FlyBase] tmod-PI / FBpp0291321 [FlyBase] tmod-PF / FBpp0085022 [FlyBase] tmod-PD / FBpp0085021 [FlyBase] tmod-PE / FBpp0085020 [FlyBase]
Description(s) found: Found 57 descriptions. SHOW ALL	The gene tropomodulin is referred to in FlyBase by the symbol Dmel\tmod (CG1539, FBgn0082582). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:26358336..26404627. It has the cytological map location 99F7-99F8. Based on sequence similarity, it is predicted to have molecular function</span>: actin binding. Based on sequence similarity, it is predicted to be involved in the biological process</span>: cytoskeleton organization. 24 alleles are reported. The phenotypes of these alleles are annotated with: striated muscle thin filament; indirect flight muscle. It has 12 annotated transcripts and 12 annotated polypeptides. [FlyBase] The gene tropomodulin is referred to in FlyBase by the symbol Dmel\tmod (CG1539, FBgn0082582). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:26358336..26404627. It has the cytological map location 99F7-99F8. Based on sequence similarity, it is predicted to have molecular function</span>: actin binding. Based on sequence similarity, it is predicted to be involved in the biological process</span>: cytoskeleton organization. 24 alleles are reported. The phenotypes of these alleles are annotated with: striated muscle thin filament; indirect flight muscle. It has 12 annotated transcripts and 12 annotated polypeptides. [FlyBase] The gene tropomodulin is referred to in FlyBase by the symbol Dmel\tmod (CG1539, FBgn0082582). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:26358336..26404627. It has the cytological map location 99F7-99F8. Based on sequence similarity, it is predicted to have molecular function</span>: actin binding. Based on sequence similarity, it is predicted to be involved in the biological process</span>: cytoskeleton organization. 24 alleles are reported. The phenotypes of these alleles are annotated with: striated muscle thin filament; indirect flight muscle. It has 12 annotated transcripts and 12 annotated polypeptides. [FlyBase] The gene tropomodulin is referred to in FlyBase by the symbol Dmel\tmod (CG1539, FBgn0082582). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:26358336..26404627. It has the cytological map location 99F7-99F8. Based on sequence similarity, it is predicted to have molecular function</span>: actin binding. Based on sequence similarity, it is predicted to be involved in the biological process</span>: cytoskeleton organization. 24 alleles are reported. The phenotypes of these alleles are annotated with: striated muscle thin filament; indirect flight muscle. It has 12 annotated transcripts and 12 annotated polypeptides. [FlyBase] The gene tropomodulin is referred to in FlyBase by the symbol Dmel\tmod (CG1539, FBgn0082582). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:26358336..26404627. It has the cytological map location 99F7-99F8. Based on sequence similarity, it is predicted to have molecular function</span>: actin binding. Based on sequence similarity, it is predicted to be involved in the biological process</span>: cytoskeleton organization. 24 alleles are reported. The phenotypes of these alleles are annotated with: striated muscle thin filament; indirect flight muscle. It has 12 annotated transcripts and 12 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	439 amino acids
Gene Ontology:
Cellular Component:	cytoskeleton [IEA]
Biological Process:	cytoskeleton organization [ISS]
Molecular Function:	actin binding [ISS] tropomyosin binding [IEA][NAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDIEDVFGG SAEETKPEPD AQSKTSVVTE HTEEVIPGET EKMVTETIDE DGDVVEETTE  60
   61 VTRKTVKRTM KITETSATTK TTTLTTPAKL YGKDLSEYDD VDVESLLAQL SPEEITILAK 120
  121 EVDPDDNFLP PDQRNSYECT KEATGPLNRK QLIEHINKQA IETPDQPEFE PFVQGKVRGK 180
  181 KWVPPPRDAR DIEAEEQIAI DMGEEYEHAL NDATQEEIID LAAILGFHSM MNQDQYHASL 240
  241 LNKGQPVGLG WDGITKSTQQ KLFPMDPPNN TDVEESIKRV KDDDSKLIDL NLNNIKNISD 300
  301 EKLEQLFAAL PQNEHLEVLS LTNVGLTDKT ALLLAAAIEK SKTLRVLNVE TNFISPPVIV 360
  361 KLVQALLKCH TIEEFRASNQ RSAVLGNKIE MEITDLVEKN SSLLRLGLHL EFNDARHRVA 420
  421 AHLQRNIDRI RVKRLNQRK

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..109]	deduced	N/A	No confident structure predictions are available.
2	View Details	[110..245]	Pfam	7.744727	No description for PF03250.5 was found. No confident structure predictions are available.
3	View Details	[246..439]	PSI-BLAST	20.522879	Tropomodulin C-terminal domain

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: tmod-PL, tmod-PE...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: