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Protein Overview: CG2014-PA, FBpp0...

General Information:
Name(s) found: FBpp0308934 [FlyBase]
CG2014-PA / FBpp0084806 [FlyBase]
Description(s) found:
Found 24 descriptions.
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  • type=protein; loc=3R:25341567..25342205; ID=FBpp0308934; name=CG2014-PB; parent=FBgn0039669,FBtr0339902; dbxref=FlyBase:FBpp0308934,FlyBase_Annotation_IDs:CG2014-PB; MD5=d8601c29c595e2fc6ea3f0819307e78e; length=212; release=r5.56; species=Dmel; [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\CG2014 (CG2014, FBgn0039669). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:25341535..25342249. It has the cytological map location 99B2. Based on sequence similarity, it is predicted to have molecular function</span>: NADH dehydrogenase activity; NADH dehydrogenase (ubiquinone) activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: mitochondrial electron transport, NADH to ubiquinone. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 212 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial respiratory chain complex I [ISS]
    Biological Process: mitochondrial electron transport, NADH to ubiquinone [ISS]
    Molecular Function: NADH dehydrogenase activity [ISS]
    quinone binding [IEA]
    NADH dehydrogenase (ubiquinone) activity [ISS]
    4 iron, 4 sulfur cluster binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MISFLKLARN PGQLLLPGSG VLQSQWLRGQ KTMPVYDYRC QNPPKWGYSA FGRNQKTWGE  60
   61 WTCARLDDLL NWGRKGSLWP LTFGLACCAV EMMHIAAPRY DMDRYGVVFR ASPRQADVLI 120
  121 VAGTLTNKMA PAFRKIYDQM PEPRWVISMG SCANGGGYYH YSYSVVRGCD RIVPVDIYVP 180
  181 GCPPTAEALM YGILQLQKKV KRMRTLQMWY RK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..212] PSI-BLAST 53.522879 Crystal structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • NADH dehydrogenase activity
    		•  13.9361001493201 bayes_pls_golite062009
  • NADH dehydrogenase (quinone) activity
    		•  12.823760326196 bayes_pls_golite062009
  • NADH dehydrogenase (ubiquinone) activity
    		•  12.8237449606378 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
    		•  12.2946357205778 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH
    		•  11.5463682902166 bayes_pls_golite062009
  • oxidoreductase activity
    		•  6.65509281399906 bayes_pls_golite062009
  • oxidoreduction-driven active transmembrane transporter activity
    		•  3.12366321374445 bayes_pls_golite062009
  • 4 iron, 4 sulfur cluster binding
    		•  2.30490418238429 bayes_pls_golite062009
  • catalytic activity
    		•  1.41356903593784 bayes_pls_golite062009
  • iron-sulfur cluster binding
    		•  1.3943220140881 bayes_pls_golite062009
  • metal cluster binding
    		•  1.3943220140881 bayes_pls_golite062009
  • binding
    		•  1.15717679472768 bayes_pls_golite062009
  • protein binding
    		•  0.403035218757706 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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