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Protein Overview: exo84-PA

General Information:
Name(s) found: exo84-PA / FBpp0084350 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\exo84 (CG6095, FBgn0260946). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:21875451..21877957. It has the cytological map location 96F10. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: contractile ring contraction involved in cytokinesis during cell cycle; meiotic spindle stabilization; cytokinesis; cytokinesis after meiosis II; maintenance of epithelial cell apical/basal polarity; cytokinesis after meiosis I. 9 alleles are reported. The phenotypes of these alleles are annotated with: epidermal cell; Nebenkern. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 671 amino acids

    Gene Ontology:
    Cellular Component: exocyst [ISS][NAS]
    Biological Process: synaptic vesicle targeting [NAS]
    synaptic vesicle docking during exocytosis [NAS]
    vesicle-mediated transport [ISS]
    contractile ring contraction involved in cell cycle cytokinesis [IMP]
    maintenance of epithelial cell apical/basal polarity [IMP]
    cytokinesis after meiosis I [IMP]
    intracellular transport [NAS]
    cytokinesis [IMP]
    meiotic spindle stabilization [IMP]
    cytokinesis after meiosis II [IMP]
    neurotransmitter secretion [NAS]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKEFDDFNFS VEKYTKDLTR ECVGGSDLQQ RKKEIEAYNE TTAATLKQTC KKNYMEFIQT  60
   61 AKEISHLESE MYQLSHILIE QRNILATMTD GKTSSHLKAE SLEAESTTAT EDLENSHATR 120
  121 AVKEMVQGFN GNLEGKTFLN EGALIELDSN DYRPIQRVFF FLFNDVLIVC KVKHDKRLDF 180
  181 LTEYDPKKIA VINIKDLDGV KNAINIITPD GSKIYQSITA AGKTEWIEKL EEAFRFDQQK 240
  241 KPKKGQAPQP PTRAKQQSKA STPEKETTPQ SPGQPKSLED ETPEWLSTAS EEIQTLVAQR 300
  301 HFEDAQELIK RTQDFLRNEN RKKLPLADAI ETKVKQQELK LINVLLKELS NSHNRNLQIA 360
  361 LRAAKRPLKI LVEMGRYRQA SATLLKVCAV SLRVAQREAR RNNADISELF FCDLTQVACD 420
  421 FLTAFEKQPA CVSALVVWCN AELQYFASQL IKHYLTKGTS LESVAKCVER VRKPSTKLTE 480
  481 IGLDISYHLE GLLRTTLESL IEESKERLLD SVGRTEESWQ PYNLQTKSNL KRLLLELDVL 540
  541 GIDVRAQATG DTWINLTQST VVFIRHFLQL TEYCGCLAKC ETLLQSLELL LKELFIAQHS 600
  601 LKPPSDMAVD PNFVMKNKIF LVDNLLPIAI DKFRQISGRQ CEGLRELHTK MSRQQGAPVP 660
  661 RQRSVYTTDV F

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..256] PSI-BLAST 24.045757 No description for 2dfkA was found.
    2 View Details [257..542] PSI-BLAST 25.39794 Crystal Structure of the Exo84p C-terminal Domains
    3 View Details [543..671] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

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    Created and Maintained by: Michael Riffle