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Protein Overview: AP-1sigma-PA

General Information:
Name(s) found: AP-1sigma-PA / FBpp0083884 [FlyBase]
Description(s) found:
Found 22 descriptions.
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  • The gene AP-1Ã?&#143;Ã?&#131; is referred to in FlyBase by the symbol Dmel\AP-1Ã?&#143;Ã?&#131; (CG5864, FBgn0039132). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:19784376..19788277. It has the cytological map location 95D1. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: protein binding; protein transporter activity. It is reported to be involved in the biological process</span>: vesicle coating; neurotransmitter secretion; synaptic vesicle coating. 6 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 157 amino acids

    Gene Ontology:
    Cellular Component: synaptic vesicle [TAS]
    clathrin coat of trans-Golgi network vesicle [IEA]
    clathrin adaptor complex [IEA]
    coated vesicle [TAS]
    Biological Process: vesicle coating [TAS]
    vesicle-mediated transport [IEA]
    synaptic vesicle coating [TAS]
    intracellular protein transport [IEA]
    neurotransmitter secretion [NAS]
    Molecular Function: protein binding [IEA]
    protein transporter activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMLFMLLFSR QGKLRLQKWY MAYPDKVKKK ITRELVTTIL ARKPKMCSFL EWKDCKIVYK  60
   61 RYASLYFCCA IEQNDNELLT LEIIHRYVEL LDKYFGSVCE LDIIFNFEKA YFILDELLIG 120
  121 GEIQETSKKN VLKAIASQDL LQEDETPQSF FDDHGLG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..157] PSI-BLAST 39.522879 AP1 clathrin adaptor core


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle