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Protein Overview: FBpp0307578

General Information:
Name(s) found: FBpp0307578 [FlyBase]
Description(s) found:
Found 23 descriptions.
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  • type=protein; loc=3R:join(19008642..19008782,19009166..19009886,19009945..19010681); ID=FBpp0307578; name=Irk1-PD; parent=FBgn0265042,FBtr0336475; dbxref=REFSEQ:NP_651131,GB_protein:AAF56107,FlyBase:FBpp0307578,FlyBase_Annotation_IDs:CG44159-PD; MD5=32e22df3475464b0006ee0b3177a82f4; length=532; release=r5.56; species=Dmel; [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 532 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [IDA]
    Biological Process: potassium ion transport [IDA]
    regulation of membrane potential [IDA]
    Molecular Function: ATP-activated inward rectifier potassium channel activity [ISS]
    inward rectifier potassium channel activity [IDA][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYILLFRFRY RQTRFSSRRV RKRVVFKHGE CNVVQGNVAK RRRRYLQDIF TTLVDAQWRW  60
   61 TLLVFAASFV FSWAFFGFIW WIIAYAHNDL EYTNLKNQSP DLVANITHTV CVTQVSNMMS 120
  121 AFLYSVETQT TIGYGNRYVT EECPEAIFTM CIQCITGVFI QAFMVGIVFA KLSRPKKRAQ 180
  181 TLLFSRNAVI CHRDGVPCLM FRVGDMRKSH IIEAHVRAQI IRKKVTKEGE VLPFYQQELH 240
  241 IGADGGEDRL MFIWPTTIVH KIDRNSPLYM LSASDMLKER FEVVVMLEGV IESTGMTTQA 300
  301 RSSYLPSEVL WGHRFVNVVS FRKETGEYEV DYTLFNNTYD VDTPLCSAKQ LDELKSEYSK 360
  361 SAKCVNAPFA DRTLSASLFQ RIASAASVDH LDPASDESLD SGRLQIRSHS IPNGVLASEL 420
  421 EPLNNNKHGA SFTMGGLTIT TTAPSIPNLS SINEKTNSGN SINSSNYSNN NSLSTLTGGG 480
  481 SAASGPGGGI TIVAGSGNHG GAGGGGGGGG RHKSNPRRLS IKQDQLPIDS IC

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..342] PSI-BLAST 80.69897 No description for 2qksA was found.
    2 View Details [343..458] PSI-BLAST 62.0 Crystal Structure of Cytoplasmic Domains of IRK1 (Kir2.1) channel
    3 View Details [459..532] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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