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Protein Overview: CG6439-PA, CG6439-PB

General Information:
Name(s) found: CG6439-PB / FBpp0290012 [FlyBase]
CG6439-PA / FBpp0083588 [FlyBase]
Description(s) found:
Found 29 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG6439 (CG6439, FBgn0038922). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:17842264..17845104. It has the cytological map location 93F14-94A1. Based on sequence similarity, it is predicted to have molecular function</span>: isocitrate dehydrogenase (NAD+) activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: tricarboxylic acid cycle. 5 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\CG6439 (CG6439, FBgn0038922). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:17842264..17845104. It has the cytological map location 93F14-94A1. Based on sequence similarity, it is predicted to have molecular function</span>: isocitrate dehydrogenase (NAD+) activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: tricarboxylic acid cycle. 5 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 370 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [ISS]
    Biological Process: tricarboxylic acid cycle [ISS]
    oxidation reduction [IEA]
    Molecular Function: magnesium ion binding [IEA]
    isocitrate dehydrogenase (NAD+) activity [ISS]
    NAD or NADH binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSMLARTVGR TFMQAAAARS LHTTSTLRAT DNYGANRTTC TLIPGDGVGP ELVYSLQEVF  60
   61 KAASVPVDFE CYFLSEINPV LSAKLEDVVA SIQKNKVCIK GVLATPDYSN VGDLQTLNMK 120
  121 LRNDLDLYAN VVHVRSLPGV KTRHTNIDTV IIREQTEGEY SALEHESVPG IVECLKIITA 180
  181 KKSMRIAKFA FDYATKNQRK KVTAVHKANI MKLGDGLFLR SCEEVSRLYP RIQFEKMIVD 240
  241 NTTMQMVSNP NQFDVMVTPN LYGAIVDNLA SGLVGGAGVV AGASYSSESV VFEPGARHTF 300
  301 AEAVGKNVAN PTAMLLCGVK LLRHINLPTY GEIIQNAINK VLNDGKVRTK DLGGQSTTQD 360
  361 FTRAIILNMS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..370] PSI-BLAST 101.0 No description for 2d1cA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.57

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle