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Protein Overview: AP-2sigma-PA

General Information:
Name(s) found: AP-2sigma-PA / FBpp0083502 [FlyBase]
Description(s) found:
Found 22 descriptions.
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  • The gene AP-2Ã?&#143;Ã?&#131; is referred to in FlyBase by the symbol Dmel\AP-2Ã?&#143;Ã?&#131; (CG6056, FBgn0043012). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:17094931..17095799. It has the cytological map location 93D2. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: protein binding; protein transporter activity. It is reported to be involved in the biological process</span>: vesicle coating; neurotransmitter secretion; synaptic vesicle coating. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 142 amino acids

    Gene Ontology:
    Cellular Component: membrane coat [IEA]
    synaptic vesicle [TAS]
    coated vesicle [TAS]
    Biological Process: vesicle coating [TAS]
    vesicle-mediated transport [IEA]
    synaptic vesicle coating [TAS]
    intracellular protein transport [IEA]
    neurotransmitter secretion [NAS]
    Molecular Function: protein binding [IEA]
    protein transporter activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIRFILIQNR AGKTRLAKWY MNFDDDEKQK LIEEVHAVVT VRDAKHTNFV EFRNFKIVYR  60
   61 RYAGLYFCIC VDVNDNNLCY LEAIHNFVEV LNEYFHNVCE LDLVFNFYKV YSVVDEMFLA 120
  121 GEIRETSQTK VLKQLLTLNS LE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..142] PSI-BLAST 37.30103 Sigma2 adaptin (clathrin coat assembly protein AP17)


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle