Protein Overview: FBpp0297442, FBp...

General Information:
Name(s) found:	FBpp0297442 [FlyBase] FBpp0297441 [FlyBase] FBpp0297440 [FlyBase] Cortactin-PA / FBpp0083441 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|7300693\|gb\|AAF55840.1\| cortactin [Drosophila melanogaster] [NCBI NR] gi\|24648611\|ref\|NP_524426.2\| cortactin [Drosophila melanogaster] [NCBI NR] gi\|15291859\|gb\|AAK93198.1\| LD29964p [Drosophila melanogaster] [NCBI NR] type=protein; loc=3R:complement(16887948..16889056,16889148..16889551,16889620..16889786); ID=FBpp0297442; name=Cortactin-PD; parent=FBgn0025865,FBtr0306349; dbxref=REFSEQ:NP_001247224,GB_protein:AFH06542,FlyBase:FBpp0297442,FlyBase_Annotation_IDs:CG3637-PD; MD5=f9df6ebf38c67c333b6d660cdc9e6f5a; length=559; release=r5.56; species=Dmel; [FlyBase] type=protein; loc=3R:complement(16887948..16889056,16889148..16889551,16889620..16889786); ID=FBpp0297441; name=Cortactin-PC; parent=FBgn0025865,FBtr0306348; dbxref=REFSEQ:NP_001247223,GB_protein:AFH06541,FlyBase:FBpp0297441,FlyBase_Annotation_IDs:CG3637-PC; MD5=f9df6ebf38c67c333b6d660cdc9e6f5a; length=559; release=r5.56; species=Dmel; [FlyBase] type=protein; loc=3R:complement(16887948..16889056,16889148..16889551,16889620..16889786); ID=FBpp0297440; name=Cortactin-PB; parent=FBgn0025865,FBtr0306347; dbxref=REFSEQ:NP_001247222,GB_protein:AFH06540,FlyBase:FBpp0297440,FlyBase_Annotation_IDs:CG3637-PB; MD5=f9df6ebf38c67c333b6d660cdc9e6f5a; length=559; release=r5.56; species=Dmel; [FlyBase] The gene Cortactin is referred to in FlyBase by the symbol Dmel\Cortactin (CG3637, FBgn0025865). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:16887402..16890185. It has the cytological map location 93B8-93B9. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: regulation of cell shape; border follicle cell migration; ovarian ring canal formation. 18 alleles are reported. The phenotypes of these alleles are annotated with: nurse follicle cell; nurse cell ring canal; egg; border follicle cell. It has one annotated transcript and one annotated polypeptide. [FlyBase] >CG3637-PA translation from_gene[CG3637 Cortactin FBgn0025865] seq_release:3 mol_weight=61083 cds_boundaries:(3R:16,887,968..16,889,803[-]) aa_length:559 transcript_info:[CG3637-RA seq_release:3] gene_info:[gene symbol:Cortactin FBgn0025865 gene_bounda [hmr_yeast5_DM3-1_pombe.fasta] (Q9VDF4) Cortactin protein (LD29964P) [DrosMelano7227.FASTAC.txt] (AE003733) Cortactin gene product [Drosophila melanogaster] [yeastflysequest.fasta] CG3637-PA [Drosophila melanogaster]gi\|15291859\|gb\|AAK93198.1\| LD29964p [Drosophila melanogaster]gi\|24648611\|ref\|NP_524426.2\| CG3637-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas] type=protein; loc=3R:complement(16887948..16889056,16889148..16889551,16889620..16889786); ID=FBpp0083441; name=Cortactin-PA; parent=FBgn0025865,FBtr0084039; dbxref=FlyBase:FBpp0083441,FlyBase_Annotation_IDs:CG3637-PA,GB_protein:AAF55840.1,REFSEQ:NP_52442 [fly-100309-contam.fasta] LD29964p [Drosophila melanogaster] [nr-271106-contam.fasta] Cortactin CG3637-PA [Drosophila melanogaster] [nr-271106-contam.fasta] CG3637-PA [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=3R:complement(16887948..16889056,16889148..16889551,16889620..16889786); ID=FBpp0083441; name=Cortactin-PA; parent=FBgn0025865,FBtr0084039; dbxref=FlyBase:FBpp0083441,FlyBase_Annotation_IDs:CG3637-PA,GB_protein:AAF55840.1,REFSEQ:NP_524426,GB_protein:AAF55840; MD5=f9df6ebf38c67c333b6d660cdc9e6f5a; length=559; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=3R:complement(16887948..16889056,16889148..16889551,16889620..16889786); ID=FBpp0083441; name=Cortactin-PA; parent=FBgn0025865,FBtr0084039; dbxref=FlyBase:FBpp0083441,FlyBase_Annotation_IDs:CG3637-PA,GB_protein:AAF55840.1,REFSEQ:NP_524426,GB_protein:AAF55840; MD5=f9df6ebf38c67c333b6d660cdc9e6f5a; length=559; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] Cortactin OS=Drosophila melanogaster GN=Cortactin PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=3R:complement(16887948..16889056,16889148..16889551,16889620..16889786); ID=FBpp0083441; name=Cortactin-PA; parent=FBgn0025865,FBtr0084039; dbxref=FlyBase:FBpp0083441,FlyBase_Annotation_IDs:CG3637-PA,GB_protein:AAF55840.1,REFSEQ:NP_524426,GB_protein:AAF55840,FlyMine:FBpp0083441,modMine:FBpp0083441; MD5=f9df6ebf38c67c333b6d660cdc9e6f5a; length=559; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=3R:complement(16887948..16889056,16889148..16889551,16889620..16889786); ID=FBpp0297440; name=Cortactin-PB; parent=FBgn0025865,FBtr0306347; dbxref=REFSEQ:NP_001247222,GB_protein:AFH06540,FlyBase:FBpp0297440,FlyBase_Annotation_IDs:CG3637-PB; MD5=f9df6ebf38c67c333b6d660cdc9e6f5a; length=559; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=3R:complement(16887948..16889056,16889148..16889551,16889620..16889786); ID=FBpp0297441; name=Cortactin-PC; parent=FBgn0025865,FBtr0306348; dbxref=REFSEQ:NP_001247223,GB_protein:AFH06541,FlyBase:FBpp0297441,FlyBase_Annotation_IDs:CG3637-PC; MD5=f9df6ebf38c67c333b6d660cdc9e6f5a; length=559; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=3R:complement(16887948..16889056,16889148..16889551,16889620..16889786); ID=FBpp0297442; name=Cortactin-PD; parent=FBgn0025865,FBtr0306349; dbxref=REFSEQ:NP_001247224,GB_protein:AFH06542,FlyBase:FBpp0297442,FlyBase_Annotation_IDs:CG3637-PD; MD5=f9df6ebf38c67c333b6d660cdc9e6f5a; length=559; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=3R:complement(join(21063898..21064064,21063426..21063829,21062226..21063334)); ID=FBpp0083441; name=Cortactin-PA; parent=FBgn0025865,FBtr0084039; dbxref=FlyBase:FBpp0083441,FlyBase_Annotation_IDs:CG3637-PA,GB_protein:AAF55840.1,REFSEQ:NP_524426,GB_protein:AAF55840,FlyMine:FBpp0083441,modMine:FBpp0083441; MD5=f9df6ebf38c67c333b6d660cdc9e6f5a; length=559; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=3R:complement(join(21063898..21064064,21063426..21063829,21062226..21063334)); ID=FBpp0297440; name=Cortactin-PB; parent=FBgn0025865,FBtr0306347; dbxref=REFSEQ:NP_001247222,GB_protein:AFH06540,FlyBase:FBpp0297440,FlyBase_Annotation_IDs:CG3637-PB; MD5=f9df6ebf38c67c333b6d660cdc9e6f5a; length=559; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=3R:complement(join(21063898..21064064,21063426..21063829,21062226..21063334)); ID=FBpp0297441; name=Cortactin-PC; parent=FBgn0025865,FBtr0306348; dbxref=REFSEQ:NP_001247223,GB_protein:AFH06541,FlyBase:FBpp0297441,FlyBase_Annotation_IDs:CG3637-PC; MD5=f9df6ebf38c67c333b6d660cdc9e6f5a; length=559; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=3R:complement(join(21063898..21064064,21063426..21063829,21062226..21063334)); ID=FBpp0297442; name=Cortactin-PD; parent=FBgn0025865,FBtr0306349; dbxref=REFSEQ:NP_001247224,GB_protein:AFH06542,FlyBase:FBpp0297442,FlyBase_Annotation_IDs:CG3637-PD; MD5=f9df6ebf38c67c333b6d660cdc9e6f5a; length=559; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=3R:complement(join(21063898..21064064,21063426..21063829,21062226..21063334)); ID=FBpp0083441; name=Cortactin-PA; parent=FBgn0025865,FBtr0084039; dbxref=FlyBase:FBpp0083441,FlyBase_Annotation_IDs:CG3637-PA,GB_protein:AAF55840.1,REFSEQ:NP_524426,GB_protein:AAF55840,FlyMine:FBpp0083441,modMine:FBpp0083441; MD5=f9df6ebf38c67c333b6d660cdc9e6f5a; length=559; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] type=protein; loc=3R:complement(join(21063898..21064064,21063426..21063829,21062226..21063334)); ID=FBpp0297440; name=Cortactin-PB; parent=FBgn0025865,FBtr0306347; dbxref=REFSEQ:NP_001247222,GB_protein:AFH06540,FlyBase:FBpp0297440,FlyBase_Annotation_IDs:CG3637-PB; MD5=f9df6ebf38c67c333b6d660cdc9e6f5a; length=559; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] type=protein; loc=3R:complement(join(21063898..21064064,21063426..21063829,21062226..21063334)); ID=FBpp0297441; name=Cortactin-PC; parent=FBgn0025865,FBtr0306348; dbxref=REFSEQ:NP_001247223,GB_protein:AFH06541,FlyBase:FBpp0297441,FlyBase_Annotation_IDs:CG3637-PC; MD5=f9df6ebf38c67c333b6d660cdc9e6f5a; length=559; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] type=protein; loc=3R:complement(join(21063898..21064064,21063426..21063829,21062226..21063334)); ID=FBpp0297442; name=Cortactin-PD; parent=FBgn0025865,FBtr0306349; dbxref=REFSEQ:NP_001247224,GB_protein:AFH06542,FlyBase:FBpp0297442,FlyBase_Annotation_IDs:CG3637-PD; MD5=f9df6ebf38c67c333b6d660cdc9e6f5a; length=559; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] Cortactin, isoform A OS=Drosophila melanogaster GN=Cortactin PE=1 SV=1 [DROME.fasta.20160308] FBpp0083441 type=protein; loc=3R:complement(join(21063898..21064064,21063426..21063829,21062226..21063334)); ID=FBpp0083441; name=Cortactin-PA; parent=FBgn0025865,FBtr0084039; dbxref=FlyBase:FBpp0083441,FlyBase_Annotation_IDs:CG3637-PA,GB_protein:AAF55840.1,REFSEQ:NP_524426,GB_protein:AAF55840,FlyMine:FBpp0083441,modMine:FBpp0083441; MD5=f9df6ebf38c67c333b6d660cdc9e6f5a; length=559; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] FBpp0297440 type=protein; loc=3R:complement(join(21063898..21064064,21063426..21063829,21062226..21063334)); ID=FBpp0297440; name=Cortactin-PB; parent=FBgn0025865,FBtr0306347; dbxref=REFSEQ:NP_001247222,GB_protein:AFH06540,FlyBase:FBpp0297440,FlyBase_Annotation_IDs:CG3637-PB; MD5=f9df6ebf38c67c333b6d660cdc9e6f5a; length=559; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] FBpp0297441 type=protein; loc=3R:complement(join(21063898..21064064,21063426..21063829,21062226..21063334)); ID=FBpp0297441; name=Cortactin-PC; parent=FBgn0025865,FBtr0306348; dbxref=REFSEQ:NP_001247223,GB_protein:AFH06541,FlyBase:FBpp0297441,FlyBase_Annotation_IDs:CG3637-PC; MD5=f9df6ebf38c67c333b6d660cdc9e6f5a; length=559; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] FBpp0297442 type=protein; loc=3R:complement(join(21063898..21064064,21063426..21063829,21062226..21063334)); ID=FBpp0297442; name=Cortactin-PD; parent=FBgn0025865,FBtr0306349; dbxref=REFSEQ:NP_001247224,GB_protein:AFH06542,FlyBase:FBpp0297442,FlyBase_Annotation_IDs:CG3637-PD; MD5=f9df6ebf38c67c333b6d660cdc9e6f5a; length=559; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=3R:complement(join(21063898..21064064,21063426..21063829,21062226..21063334)); ID=FBpp0083441; name=Cortactin-PA; parent=FBgn0025865,FBtr0084039; dbxref=FlyBase:FBpp0083441,FlyBase_Annotation_IDs:CG3637-PA,GB_protein:AAF55840.1,REFSEQ:NP_524426,GB_protein:AAF55840,UniProt/TrEMBL:Q9VDF4,FlyMine:FBpp0083441,modMine:FBpp0083441; MD5=f9df6ebf38c67c333b6d660cdc9e6f5a; length=559; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta] type=protein; loc=3R:complement(join(21063898..21064064,21063426..21063829,21062226..21063334)); ID=FBpp0297440; name=Cortactin-PB; parent=FBgn0025865,FBtr0306347; dbxref=REFSEQ:NP_001247222,GB_protein:AFH06540,FlyBase:FBpp0297440,FlyBase_Annotation_IDs:CG3637-PB,UniProt/TrEMBL:Q9VDF4; MD5=f9df6ebf38c67c333b6d660cdc9e6f5a; length=559; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta] type=protein; loc=3R:complement(join(21063898..21064064,21063426..21063829,21062226..21063334)); ID=FBpp0297441; name=Cortactin-PC; parent=FBgn0025865,FBtr0306348; dbxref=REFSEQ:NP_001247223,GB_protein:AFH06541,FlyBase:FBpp0297441,FlyBase_Annotation_IDs:CG3637-PC,UniProt/TrEMBL:Q9VDF4; MD5=f9df6ebf38c67c333b6d660cdc9e6f5a; length=559; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta] type=protein; loc=3R:complement(join(21063898..21064064,21063426..21063829,21062226..21063334)); ID=FBpp0297442; name=Cortactin-PD; parent=FBgn0025865,FBtr0306349; dbxref=REFSEQ:NP_001247224,GB_protein:AFH06542,FlyBase:FBpp0297442,FlyBase_Annotation_IDs:CG3637-PD,UniProt/TrEMBL:Q9VDF4; MD5=f9df6ebf38c67c333b6d660cdc9e6f5a; length=559; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	559 amino acids
Gene Ontology:
Cellular Component:	cytoskeleton [ISS] sperm individualization complex [IDA]
Biological Process:	regulation of cell shape [IMP] cytoskeleton organization [ISS] female germline ring canal formation [IMP] border follicle cell migration [IMP]
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWKASAGHQI QATSAASAED DDWETDPDFV NDVSEQEQRW GSKTIDGSGR TAGTIDMDKL  60
   61 REETEQADLD KKKQLLKDQN AGYGYGGKFG VEKDRMDKSA VGHDYQGKVG KHASQKDYSD 120
  121 GFGGKFGVQE DRKDKSAVGW DHVEKVEKHA SQKDYATGFG GKFGVQSDRV DKSAVGWDHI 180
  181 EKVEKHESQK DYSKGFGGKF GVQEDRKDKS AVGWDHKEAP QKHASQVDHK VKPVIEGAKP 240
  241 SNLRAKFENL AKNSEEESRK RAEEQKRLRE AKDKRDREEA AKKTVAENTP RTSTEAPPPK 300
  301 GSRAAIQTGR TGGIGNAISA FNQMQSPVSE TPPARKEPII IPKAQPVKIE LEAKEEPTAS 360
  361 TTSAAVAPTP TVVPAREPET APVAKAAAPP PDVVPQIEVE TVDTPPRSEP QSPVYVPTPQ 420
  421 PEVHAQVQVQ PEPQPQADPE PVVEEEPLYQ NQAEIKAASP LPPTNGTVSE AVAPSGTATV 480
  481 PEEAIYANSD NLADYLEDTG IHAIALYDYQ AADDDEISFD PDDVITHIEK IDDGWWRGLC 540
  541 KNRYGLFPAN YVQVVGQNS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..197]	MSA	2.110934	View MSA. No confident structure predictions are available.
2	View Details	[198..390]	deduced	N/A	No confident structure predictions are available.
3	View Details	[391..457]	deduced	N/A	No confident structure predictions are available.
4	View Details	[458..559]	PSI-BLAST	20.39794	Solution structures of the SH3 domain of human Src substrate cortactin

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.63

Protein Overview: FBpp0297442, FBp...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: