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Protein Overview: Rlip-PA

General Information:
Name(s) found: Rlip-PA / FBpp0083406 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • The gene Ral interacting protein is referred to in FlyBase by the symbol Dmel\Rlip (CG11622, FBgn0026056). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:16843423..16846475. It has the cytological map location 93B4. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: receptor-mediated endocytosis. 8 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 625 amino acids

    Gene Ontology:
    Cellular Component: intracellular [IEA]
    Biological Process: signal transduction [IEA]
    receptor-mediated endocytosis [IMP]
    Molecular Function: protein binding [IPI]
    Ral GTPase activator activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDFDSPEEKE FPGLYASEAA DAKSRKSKEE SDFSEDHDHS KKDLLIGRRK DKKEKGKDRG  60
   61 YAALEGESSP EEELDTKSPS KSKKSKTFKF TSSKSKEKRE KSRDKSEKDS KHAEEEPSVS 120
  121 HKVKEKERDK EKDRDEPKKK DKEEKRKEKD KKADKKDKKD KKSKQLSQQQ DDVSAAEEVL 180
  181 ALGYPVFGVS VSLATERSRC HDGVDIPLVV RDCIDFLQDH LKCEQIYKIE PIKTRLMHFK 240
  241 RLYNNREHDS AVDELNLPTA CSLLKLFLRE LPEPLLTTDL VARFEEVASH PKVTTQQAEL 300
  301 QQLLEQLPKC NRTLLAWVLL HFDAVIQQER HNKLNAQSLA MLLSPTLQMS HRLMVALLCH 360
  361 CNNLFADVQL IKYVPPLTST SPKLPDTPED IQTELRKQDS LLSQIHSEMN AGFITKKREE 420
  421 QLWEVQRIIT QLKRKLRTFE KKQEKTAEEV DNSSSAPPAV ASEDTTDSKP AGTPAVSTNN 480
  481 SISQEEPKTD TLTPKDAPND FTIDPSTGFI LLPKSNPHRE NLLRLQIEYD ELMEWQNELK 540
  541 ARIVAERNEV YRLKQLYEQQ SINSQMASLA SGSQAPPESD YERIIEHYTR ENALLEHKKN 600
  601 MLGMELKEER RACIALQVEL RLQQF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..74] deduced N/A No confident structure predictions are available.
    2 View Details [75..390] PSI-BLAST 49.154902 Crystal Structure of the Human Beta2-Chimaerin
    3 View Details [391..510] deduced N/A No confident structure predictions are available.
    4 View Details [511..625] PSI-BLAST 9.30103 No description for 2v1yB was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  1.30378408278683 bayes_pls_golite062009
  • Rho GTPase activator activity
    		•  0.883269528292209 bayes_pls_golite062009
  • protein binding
    		•  0.779915873989726 bayes_pls_golite062009
  • catalytic activity
    		•  0.022300147518912 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle