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Protein Overview: Ir93a-PB

General Information:
Name(s) found: Ir93a-PB / FBpp0288997 [FlyBase]
Description(s) found:
Found 12 descriptions.
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  • The gene Ionotropic receptor 93a is referred to in FlyBase by the symbol Dmel\Ir93a (CG42315, FBgn0259215). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:16677428..16685667. It has the cytological map location 93A2. Based on sequence similarity, it is predicted to have molecular function</span>: extracellular-glutamate-gated ion channel activity. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 525 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEA]
    plasma membrane [ISS]
    Biological Process: NONE FOUND
    Molecular Function: extracellular-glutamate-gated ion channel activity [IEA][ISS]
    ionotropic glutamate receptor activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLLFLLFYS YVDQEFLKTN AKCSSCARWR VETAITWGKS QENRKFRSTP QRDAKNRNFE  60
   61 FINIGYWTPV LGFVCQELAF PHIEHHFRNI TMDILTVHNP PWQILTKNSN GVIVEHKGIV 120
  121 MEIVKELSRA LNFSYYLHEA SAWKEEDSLS TSAGGNESDE LVGSMTFRIP YRVVEMVQGN 180
  181 QFFIAAVAAT VEDPDQKPFN YTQPISVQKY SFITRKPDEV SRIYLFTAPF TVETWFCLMG 240
  241 IILLTAPTLY AINRLAPLKE MRIVGLSTVK SCFWYIFGAL LQQGGMYLPT ADSGRLVVGF 300
  301 WWIVVIVLVT TYCGNLVAFL TFPKFQPGVD YLNQLEDHKD IVQYGLRNGT FFERYVQSTT 360
  361 REDFKHYLER AKIYGSAQEE DIEAVKRGER INIDWRINLQ LIVQRHFERE KECHFALGRE 420
  421 SFVDEQIAMI VPAQSAYLHL VNRHIKSMFR MGFIERWHQM NLPSAGKCNG KSAQRQVTNH 480
  481 KVNMDDMQGC FLVLLLGFTL ALLIVCGEFW YRRFRASRKR RQFTN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..87] MSA 2.655988 View MSA. No confident structure predictions are available.
    2 View Details [88..168] PSI-BLAST 20.09691 No description for 2v3tA was found.
    3 View Details [169..525] PSI-BLAST 20.221849 Crystal Structure Of The NR2A Ligand Binding Core In Complex With Glutamate

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • catalytic activity
    		•  0.144254316055515 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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