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Protein Overview: Ir93a-PC

General Information:
Name(s) found: Ir93a-PC / FBpp0288998 [FlyBase]
Description(s) found:
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  • gi|28572148|ref|NP_650923.3| CG42315, isoform C [Drosophila melanogaster] [NCBI NR]
  • gi|28381385|gb|AAF55816.2| CG42315, isoform C [Drosophila melanogaster] [NCBI NR]
  • gi|17861392|gb|AAL39173.1| GH01149p [Drosophila melanogaster] [NCBI NR]
  • The gene Ionotropic receptor 93a is referred to in FlyBase by the symbol Dmel\Ir93a (CG42315, FBgn0259215). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:16677428..16685667. It has the cytological map location 93A2. Based on sequence similarity, it is predicted to have molecular function</span>: extracellular-glutamate-gated ion channel activity. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
  • >CG17274-PA translation from_gene[CG17274 CG17274 FBgn0038835] seq_release:3 mol_weight=73677 cds_boundaries:(3R:16,677,586..16,679,990[-]) aa_length:637 transcript_info:[CG17274-RA seq_release:3] gene_info:[gene symbol:CG17274 FBgn0038835 gene_boundar [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q8T0V7) GH01149p (CG17274-PA) [DrosMelano7227.FASTAC.txt]
  • CG17274-PA, isoform A [Drosophila melanogaster]gi|17861392|gb|AAL39173.1| GH01149p [Drosophila melanogaster]gi|28572148|ref|NP_650923.3| CG17274-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3R:complement(16677566..16678293,16678418..16678793,16678847..16679026,16679081..16679229,16679287..16679389,16679596..16679973); ID=FBpp0288998; name=CG42315-PC; parent=FBgn0259215,FBtr0299720; dbxref=FlyBase:FBpp0288998,FlyBase_Annotat [fly-100309-contam.fasta]
  • GH01149p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG17274-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3R:complement(16677566..16678293,16678418..16678793,16678847..16679026,16679081..16679229,16679287..16679389,16679596..16679973); ID=FBpp0288998; name=CG42315-PC; parent=FBgn0259215,FBtr0299720; dbxref=FlyBase:FBpp0288998,FlyBase_Annotation_IDs:CG42315-PC,REFSEQ:NP_650923,GB_protein:AAF55816; MD5=37caa419ac1492f4ef15d30bc946efc6; length=637; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3R:complement(16677566..16678293,16678418..16678793,16678847..16679026,16679081..16679229,16679287..16679389,16679596..16679973); ID=FBpp0288998; name=Ir93a-PC; parent=FBgn0259215,FBtr0299720; dbxref=FlyBase:FBpp0288998,FlyBase_Annotation_IDs:CG42315-PC,REFSEQ:NP_650923,GB_protein:AAF55816; MD5=37caa419ac1492f4ef15d30bc946efc6; length=637; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • GH01149p OS=Drosophila melanogaster GN=Ir93a PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=3R:complement(16677566..16678293,16678418..16678793,16678847..16679026,16679081..16679229,16679287..16679389,16679596..16679973); ID=FBpp0288998; name=Ir93a-PC; parent=FBgn0259215,FBtr0299720; dbxref=FlyBase:FBpp0288998,FlyBase_Annotation_IDs:CG42315-PC,REFSEQ:NP_650923,GB_protein:AAF55816,FlyMine:FBpp0288998,modMine:FBpp0288998; MD5=37caa419ac1492f4ef15d30bc946efc6; length=637; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
    • Organism: Drosophila melanogaster
    Length: 637 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEA]
    plasma membrane [ISS]
    Biological Process: NONE FOUND
    Molecular Function: extracellular-glutamate-gated ion channel activity [IEA][ISS]
    ionotropic glutamate receptor activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRQQFLVISA FHEDIIEIAE TLNMFHVGNQ WMIFVLDMVA RDFDAGTVTI NLDEGANIAF  60
   61 ALNETDPNCQ DSLNCTISEI SLALVNAISK ITVEEESIYG EISDEEWEAI RFTKQEKQAE 120
  121 ILEYMKEFLK TNAKCSSCAR WRVETAITWG KSQENRKFRS TPQRDAKNRN FEFINIGYWT 180
  181 PVLGFVCQEL AFPHIEHHFR NITMDILTVH NPPWQILTKN SNGVIVEHKG IVMEIVKELS 240
  241 RALNFSYYLH EASAWKEEDS LSTSAGGNES DELVGSMTFR IPYRVVEMVQ GNQFFIAAVA 300
  301 ATVEDPDQKP FNYTQPISVQ KYSFITRKPD EVSRIYLFTA PFTVETWFCL MGIILLTAPT 360
  361 LYAINRLAPL KEMRIVGLST VKSCFWYIFG ALLQQGGMYL PTADSGRLVV GFWWIVVIVL 420
  421 VTTYCGNLVA FLTFPKFQPG VDYLNQLEDH KDIVQYGLRN GTFFERYVQS TTREDFKHYL 480
  481 ERAKIYGSAQ EEDIEAVKRG ERINIDWRIN LQLIVQRHFE REKECHFALG RESFVDEQIA 540
  541 MIVPAQSAYL HLVNRHIKSM FRMGFIERWH QMNLPSAGKC NGKSAQRQVT NHKVNMDDMQ 600
  601 GCFLVLLLGF TLALLIVCGE FWYRRFRASR KRRQFTN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..182] MSA 6.22599 View MSA. No confident structure predictions are available.
    2 View Details [183..295] PSI-BLAST 10.09691 No description for 2ieeA was found.
    3 View Details [296..637] PSI-BLAST 20.69897 Crystal Structure Of The NR2A Ligand Binding Core In Complex With Glutamate

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • catalytic activity
    		•  0.144254316055515 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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