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Protein Overview: CG10881-PA

General Information:
Name(s) found: CG10881-PA / FBpp0083293 [FlyBase]
Description(s) found:
Found 22 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG10881 (CG10881, FBgn0038796). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:16233987..16234870. It has the cytological map location 92E8. Based on sequence similarity, it is predicted to have molecular function</span>: mRNA binding; translation initiation factor activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: translational initiation. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 273 amino acids

    Gene Ontology:
    Cellular Component: eukaryotic translation initiation factor 3 complex [ISS]
    Biological Process: translational initiation [ISS]
    Molecular Function: nucleic acid binding [IEA]
    nucleotide binding [IEA]
    translation initiation factor activity [ISS]
    zinc ion binding [IEA]
    mRNA binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKTFVTSWAD EVDADYVDGL PPSNEYIKGD FKYVTEYKFN DDGKKVKVVR TFKIEKQIVP  60
   61 KAVARRRNWV KFGDSRSDKP GPNSQTTMAS EEIFMQFIGS KDFDQTHETQ LDPGKNIAKC 120
  121 RICNGEHWSV NCPYKGTSMD SKTVMETKAN AAAAAAISDP SKTGKYVPPF MKDGGGISGS 180
  181 KNWGRGRDRD DSSAVRISNL SESMTETDLE ELVKKIGPHT KMYLAREKNS GLCKGFAYVH 240
  241 FKFRQDAAAA IEVLNGHGYD HLILCVEWSK PQP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..191] deduced N/A No confident structure predictions are available.
    2 View Details [192..273] PSI-BLAST 18.09691 solution structure of RNA binding domain in eukaryotic translation initiation factor 3 subunit 4


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle