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Protein Overview: CG4335-PA

General Information:
Name(s) found: CG4335-PA / FBpp0083302 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG4335 (CG4335, FBgn0038795). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:16232337..16233568. It has the cytological map location 92E7. Based on sequence similarity, it is predicted to have molecular function</span>: gamma-butyrobetaine dioxygenase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: oxidation reduction; carnitine biosynthetic process. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 364 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: oxidation reduction [IEA]
    carnitine biosynthetic process [IEA]
    Molecular Function: trimethyllysine dioxygenase activity [IEA]
    L-ascorbic acid binding [IEA]
    iron ion binding [IEA]
    gamma-butyrobetaine dioxygenase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLLKHPKTS QSIEINEFWL RDHCRCVECL NFETNQRRYD VLDLPADIMP LDVKYDGMNL  60
   61 QVQWSDAHKS NYDLDFIFDS QLERLIGRRS KSTNLTPWNR SIILQNERHL RFPLPQLVSS 120
  121 DNEVRSLVES LVRYGIVFID DVAPTANMTE LALRRVFPLM KTFFGEMWTF SDNPDHADTA 180
  181 YTKLYLGSHT DNTYFCDAAG LQALHCIEHS GSGGENFFVD GLHVVHELKR RYPAAYDVLC 240
  241 SVQVPGEYIE KGEHHYHTAP IIQVDPLTQE FVQLRLNVYD RAVFNTIPQA EMAEFYDSLR 300
  301 QLLLIVRDKQ QQWALKLCPG SIVLFDNWRV LHGREAYTGS RTMSGSYVQR TDFLSKARVL 360
  361 GIID

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..87] MSA 13.184996 View MSA. No confident structure predictions are available.
    2 View Details [88..364] PSI-BLAST 50.30103 Taurine/alpha-ketoglutarate dioxygenase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • damaged DNA binding
    		•  2.1600632791412 bayes_pls_golite062009
  • oxidoreductase activity
    		•  2.14660717798066 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
    		•  1.96457406152694 bayes_pls_golite062009
  • binding
    		•  0.997838210709106 bayes_pls_golite062009
  • catalytic activity
    		•  0.921320409505 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.195303464765705 bayes_pls_golite062009
  • DNA binding
    		•  0.119653205743915 bayes_pls_golite062009
  • protein binding
    		•  0.0481711987500598 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle