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Protein Overview: P5cr-PA

General Information:
Name(s) found: P5cr-PA / FBpp0083127 [FlyBase]
Description(s) found:
Found 22 descriptions.
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  • The gene Pyrroline 5-carboyxlate reductase is referred to in FlyBase by the symbol Dmel\P5cr (CG6009, FBgn0015781). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:14854659..14855881. It has the cytological map location 91E4. Based on sequence similarity, it is predicted to have molecular function</span>: pyrroline-5-carboxylate reductase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: proline biosynthetic process. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 280 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: proline biosynthetic process [IEA][ISS]
    oxidation reduction [IEA]
    Molecular Function: pyrroline-5-carboxylate reductase activity [ISS]
    binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKLDEKIGF IGGGNMAYAI GSGLVRCGIV KASQVQVSGP HIENLQRWRD LGAVTCDDNC  60
   61 MVLEHSDIVF ICVKPHMLTP CAAQLKYKHV PSAKDASKLV VSVLAGTSLE TLEEAFSFMG 120
  121 SSELKVIRTM PNTSMQVGEG CTVYTGNARV SHHDLEKIHL MLNALGLAQQ VPESMIDAVT 180
  181 GVAGCGPAFV YTIIEALADG GVKQGVPRQM ALQFAAQTLL GAAKTVLLTG KHPAVLRDEV 240
  241 CSPGGATIVG VHELEKGNLR STLINAVEKS SQRSAELGKK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..280] PSI-BLAST 46.69897 No description for 2izzA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.68

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle