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Protein Overview: gl-PA

General Information:
Name(s) found: gl-PA / FBpp0083005 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • The gene glass is referred to in FlyBase by the symbol Dmel\gl (CG7672, FBgn0004618). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:14193649..14198460. It has the cytological map location 91A3. Based on sequence similarity, it is predicted to have molecular function</span>: specific RNA polymerase II transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: entrainment of circadian clock; response to red light; ring gland development; compound eye photoreceptor fate commitment; entrainment of circadian clock by photoperiod. 82 alleles are reported. The phenotypes of these alleles are annotated with 30 unique terms, many of which group under: peripheral nervous system; external compound sense organ; nervous system; adult segment; endocrine system; multi-cell-component structure; adult brain; primordium; integumentary plate; compound cell cluster organ; rhabdomere; embryonic neuron; ectoderm derivative. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 604 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA][NAS]
    Biological Process: compound eye photoreceptor fate commitment [IMP]
    entrainment of circadian clock [IMP]
    compound eye photoreceptor development [NAS]
    ring gland development [IMP]
    entrainment of circadian clock by photoperiod [IMP]
    response to red light [IMP]
    Molecular Function: nucleic acid binding [IEA]
    transcription factor activity [NAS]
    zinc ion binding [IEA]
    specific RNA polymerase II transcription factor activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGLLYKGSKL LNTILDSLED QEGGAMYISC DVSNGGPVEP ETGYVPNNPL FGLALDSPQQ  60
   61 ECAASCVGCL SCQGSTALPI SSLTSSDFDC GGCFDPTIGV GVGIGGGHIQ ISTTPPASSG 120
  121 NGSSNNGAGG GSSGNHGYWS TDEMASTFPG LPPLDIDPLP SLFPFSPCGA SYNFAAGNPH 180
  181 QAASLSYTVH PHQMLISPNS HNHGQMHSQH QQHQHQQSQV QASHVGNSLL QSSGGNNIGS 240
  241 NGSAGGVANA ASCYYETSAG TAAPPPPPAA AMYPSMSVNV SMNMTMHHGY GAGDAGGVPM 300
  301 QCSQMNWTPP SNSTSAAAAA AAVNVLYPPL LSPGHYPASA TYSFTADFRA PAPTGLGALP 360
  361 PLTVGEKESP SPPANSSLAG YYPTGVGNQG YTPPHKSPTS YQAAALGLSL SAFEDEEDSN 420
  421 EDLDGDEGSS GGEMKPNLCR LCGKTYARPS TLKTHLRTHS GERPYRCPDC NKSFSQAANL 480
  481 TAHVRTHTGQ KPFRCPICDR RFSQSSSVTT HMRTHSGERP YRCSSCKKSF SDSSTLTKHL 540
  541 RIHSGEKPYQ CKLCLLRFSQ SGNLNRHMRV HGNNNSSNGS NGATGVGGES STGSGVGGGN 600
  601 SLLT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..135] deduced N/A No confident structure predictions are available.
    2 View Details [136..359] deduced N/A No confident structure predictions are available.
    3 View Details [360..433] PSI-BLAST 19.30103 Five-finger GLI1
    4 View Details [434..604] PSI-BLAST 62.69897 No description for 2i13A was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle