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Protein Overview: CG5285-PA

General Information:
Name(s) found: CG5285-PA / FBpp0082850 [FlyBase]
Description(s) found:
Found 18 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG5285 (CG5285, FBgn0038490). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:12976378..12977281. It has the cytological map location 89F1. Based on sequence similarity, it is predicted to have molecular function</span>: single-strand selective uracil DNA N-glycosylase activity. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 280 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: single-strand selective uracil DNA N-glycosylase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLKRKLNQQK CNLEIGEPTK TSARQGSTSE FFDKPLWLKF YETEVKLNEA LEKLNPPEST  60
   61 PFIYNPIVYA SQLHCDYLRR YMDGPKKLVF VGMNPGPNGM AQTGIPFGNV RTVKLLMQLA 120
  121 GSVDQPPVVH PKRPVAGLDC RIEEPSGVRL WELFLRLAGS MQTFSQQCFV HNFCPLAFFG 180
  181 ADGRNITPSE IRGAYKNQLG DLCLHTLEEQ LKLLQPDVIV AVGEYVHSAL KRSGYAKSNC 240
  241 VSVLRLPHPS PRSTNNTNWP EKAQAFLEEH NLIRFMRNEA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..280] PSI-BLAST 102.0 Single-strand selective monofunctional uracil-DNA glycosylase SMUG1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  1.06105429247323 bayes_pls_golite062009
  • hydrolase activity
    		•  0.68125450217484 bayes_pls_golite062009
  • hydrolase activity, acting on glycosyl bonds
    		•  0.52171393538922 bayes_pls_golite062009
  • hydrolase activity, hydrolyzing N-glycosyl compounds
    		•  0.513922158039369 bayes_pls_golite062009
  • DNA N-glycosylase activity
    		•  0.51291740673128 bayes_pls_golite062009
  • uracil DNA N-glycosylase activity
    		•  0.19043017897437 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle