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Protein Overview: CG5265-PA

General Information:
Name(s) found: CG5265-PA / FBpp0082848 [FlyBase]
Description(s) found:
Found 19 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG5265 (CG5265, FBgn0038486). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:12964829..12966856. It has the cytological map location 89F1. Based on sequence similarity, it is predicted to have molecular function</span>: carnitine O-acetyltransferase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: fatty acid metabolic process; carnitine metabolic process. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 643 amino acids

    Gene Ontology:
    Cellular Component: peroxisome [ISS]
    endoplasmic reticulum [ISS]
    mitochondrial inner membrane [ISS]
    Biological Process: fatty acid metabolic process [ISS]
    carnitine metabolic process [ISS]
    Molecular Function: carnitine O-acetyltransferase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKFRDNGKVL WNFARISALQ QTRYTFGKKM PIASYSTAKD KPKSDQPNLL KYHVLPLEEI  60
   61 LNRFMITVQP LLTPEEFKKQ EKITNEFQRK EGAKLQKLLE ETGEQEKNWL AHRWLKVAYL 120
  121 QFRSPVTCFS SPGMTFPKQK FESVHEFVDY TSRVIFGLGE FNDLVHAKKI PIVKMGKNEL 180
  181 DNSQFGKVFG TCRIPRRFTD DIVYNPCSDY VVVIYRNHFY QLKIYDKEGK LIIAPCLAVQ 240
  241 LEEIMAKEKE PGVPYGILTT DSRDNWAEAY EHLSNTPRNR VALKTIQNAM FTVSLDECTS 300
  301 PKEGRDAEEL ILTLIHGKGS KCNSANRWMD KTIQLVVNPN GHVGFTYEHS PAEGQPIAMM 360
  361 MDYVVKKMKD DPSYGECGSE NFIPAKKIKF CDVSKCVEQW LIIAQKNVDK LVQDLQMKVL 420
  421 KFDCYGKDFI KKQRLGPDSF VQMALQLAFF KLHYEPAAQY ESAHLRIFDG GRTETIRSCS 480
  481 NESLAFCHAM DDVSASAQER ASKIREAVMC HQMYAKLALL GKGVDRHLFG LKLMAVENCL 540
  541 PVPEFFSSPG YVKSTHFRMS TSQVATKYDA FMGYGPSVED GYACCYNPRE HDIILAISAW 600
  601 RHCQATDHQK IAKALAQSFA EMKDVLETCP ASKDKPPELK CKY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..643] PSI-BLAST 1000.0 Crystal structure of the M564G mutant of murine CrAT

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • carnitine O-acyltransferase activity
    		•  7.54616819269984 bayes_pls_golite062009
  • carnitine O-acetyltransferase activity
    		•  7.38318207912192 bayes_pls_golite062009
  • choline O-acetyltransferase activity
    		•  6.09272417016149 bayes_pls_golite062009
  • octanoyltransferase activity
    		•  4.52268776339565 bayes_pls_golite062009
  • O-octanoyltransferase activity
    		•  4.52268776339565 bayes_pls_golite062009
  • carnitine O-octanoyltransferase activity
    		•  4.52268776339565 bayes_pls_golite062009
  • S-acyltransferase activity
    		•  4.44987112475286 bayes_pls_golite062009
  • carnitine O-palmitoyltransferase activity
    		•  3.83467723502092 bayes_pls_golite062009
  • O-palmitoyltransferase activity
    		•  3.83467723502092 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  3.7327637835604 bayes_pls_golite062009
  • O-acyltransferase activity
    		•  3.7101056995294 bayes_pls_golite062009
  • dihydrolipoamide S-acyltransferase activity
    		•  3.56004160262054 bayes_pls_golite062009
  • dihydrolipoyllysine-residue acetyltransferase activity
    		•  3.36143851730669 bayes_pls_golite062009
  • S-acetyltransferase activity
    		•  3.32990830846882 bayes_pls_golite062009
  • acyltransferase activity
    		•  3.08588280042054 bayes_pls_golite062009
  • transferase activity, transferring acyl groups other than amino-acyl groups
    		•  3.027770031317 bayes_pls_golite062009
  • S-succinyltransferase activity
    		•  3.02354522717247 bayes_pls_golite062009
  • dihydrolipoyllysine-residue succinyltransferase activity
    		•  3.02354522717247 bayes_pls_golite062009
  • O-acetyltransferase activity
    		•  2.37098434941789 bayes_pls_golite062009
  • palmitoyltransferase activity
    		•  2.23754077046213 bayes_pls_golite062009
  • succinyltransferase activity
    		•  2.08404693277798 bayes_pls_golite062009
  • choline binding
    		•  1.59193088660278 bayes_pls_golite062009
  • catalytic activity
    		•  1.51562638409295 bayes_pls_golite062009
  • acetyltransferase activity
    		•  1.12787027896966 bayes_pls_golite062009
  • transferase activity
    		•  1.08341671157927 bayes_pls_golite062009
  • binding
    		•  0.999555841397607 bayes_pls_golite062009
  • pyruvate dehydrogenase activity
    		•  0.85838145786229 bayes_pls_golite062009
  • protein binding
    		•  0.104367069798378 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle