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Protein Overview: Actn3-PA

General Information:
Name(s) found: Actn3-PA / FBpp0082822 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • The gene Ã?&#142;Ã?± actinin 3 is referred to in FlyBase by the symbol Dmel\Actn3 (CG8953, FBgn0015008). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:12801620..12803382. It has the cytological map location 89E5. Based on sequence similarity, it is predicted to have molecular function</span>: calcium ion binding; actin filament binding; actin binding. Based on sequence similarity, it is predicted to be involved in the biological process</span>: actin filament bundle formation. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 553 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: actin filament bundle assembly [ISS]
    Molecular Function: actin filament binding [ISS]
    actin binding [ISS][NAS]
    calcium ion binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKICLGKVIL FTRSLRETFA ESQESGNQEQ SSKALVLLRC TRYIKRLSMV LTLLETEEGL  60
   61 NKVNKTLFQL DVDTILFELE CIVKEALKSL SVSRFPYQES SCTTTETLVK ESPICELNKL 120
  121 RLMLKNEKKK QELEIMGHNL IIMKEKTLVL QARKNQRAAE NRLAEKQDRI KALEECLANC 180
  181 KFQLKNVNEQ YQKLKKASNQ LIRESNQIRP QKSWSVLVGR RKGRISTRTS FVWKSLKLDQ 240
  241 SERETLMGLK KRLSEEKEIK LRAKTEMSKI RKAMDELCLG KGELQFGLQN KSETDASKDT 300
  301 LVVIDKALSA LSQYNTLKFP DCNFQLSRLM KSLYGSLTTI RDRWIRKISS AVEPTPSCLK 360
  361 SNTPSLPEPP LTVSFSTDLF WDKIYKPCTQ SNPVMPNTSL IPVLPKKQPK SLQLTCEPSV 420
  421 QYKVASRSST TAPVPKYLGK TFGDRRLSLL RWCQERVKPY GIPMYEFSAS WISGRALCAI 480
  481 IHSYLPDLID KTYLAKKKPE EVLAYGIKVA KSIGVSDSVD LIRELRQGRP NLEKIVDFVE 540
  541 ELQGYLDMYD TNI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..341] PSI-BLAST 15.69897 Heavy meromyosin subfragment
    2 View Details [342..553] PSI-BLAST 32.0 No description for 2eyiA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.83

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle