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Protein Overview: Fas1-PB

General Information:
Name(s) found: Fas1-PB / FBpp0082783 [FlyBase]
Description(s) found:
Found 25 descriptions.
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  • The gene Fasciclin 1 is referred to in FlyBase by the symbol Dmel\Fas1 (CG6588, FBgn0000634). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:12450948..12465493. It has the cytological map location 89D5-89D6. There is experimental evidence that it has the molecular function</span>: cell adhesion molecule binding. There is experimental evidence that it is involved in the biological process</span>: axon guidance; homophilic cell adhesion; calcium-independent cell-cell adhesion; neuron recognition. 26 alleles are reported. No phenotypic data is available. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 652 amino acids

    Gene Ontology:
    Cellular Component: plasma membrane [IDA][NAS]
    Biological Process: calcium-independent cell-cell adhesion [IDA]
    neuron recognition [IDA][NAS]
    axon guidance [IGI][NAS]
    neuron cell-cell adhesion [ISS][NAS]
    homophilic cell adhesion [IDA]
    Molecular Function: cell adhesion molecule binding [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLNAAALLLA LLCAANAAAA ADLADKLRDD SELSQFYSLL ESNQIANSTL SLRSCTIFVP  60
   61 TNEAFQRYKS KTAHVLYHIT TEAYTQKRLP NTVSSDMAGN PPLYITKNSN GDIFVNNARI 120
  121 IPSLSVETNS DGKRQIMHII DEVLEPLTVK AGHSDTPNNP NALKFLKNAE EFNVDNIGVR 180
  181 TYRSQVTMAK KESVYDAAGQ HTFLVPVDEG FKLSARSSLV DGKVIDGHVI PNTVIFTAAA 240
  241 QHDDPKASAA FEDLLKVTVS FFKQKNGKMY VKSNTIVGDA KHRVGVVLAE IVKANIPVSN 300
  301 GVVHLIHRPL MIIDTTVTQF LQSFKENAEN GALRKFYEVI MDNGGAVLDD INSLTEVTIL 360
  361 APSNEAWNSS NINNVLRDRN KMRQILNMHI IKDRLNVDKI RQKNANLIAQ VPTVNNNTFL 420
  421 YFNVRGEGSD TVITVEGGGV NATVIQADVA QTNGYVHIID HVLGVPYTTV LGKLESDPMM 480
  481 SDTYKMGKFS HFNDQLNNTQ RRFTYFVPRD KGWQKTELDY PSAHKKLFMA DFSYHSKSIL 540
  541 ERHLAISDKE YTMKDLVKFS QESGSVILPT FRDSLSIRVE EEAGRYVIIW NYKKINVYRP 600
  601 DVECTNGIIH VIDYPLLEEK DVVVAGGSYL PESSICIILA NLIMITVAKF LN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..315] FFAS03 6.75 Fasciclin I
    2 View Details [316..652] PSI-BLAST 60.522879 Fasciclin I


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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