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Protein Overview: Mhcl-PD

General Information:
Name(s) found: Mhcl-PD / FBpp0082687 [FlyBase]
Description(s) found:
Found 19 descriptions.
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  • The gene Myosin heavy chain-like is referred to in FlyBase by the symbol Dmel\Mhcl (CG31045, FBgn0026059). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:11894245..11923310. It has the cytological map location 89B2-89B3. Based on sequence similarity, it is predicted to have molecular function</span>: ATPase activity, coupled. The biological processes in which it is involved are not known. 6 alleles are reported. The phenotypes of these alleles are annotated with: ventral nerve cord; peripheral nervous system. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1134 amino acids

    Gene Ontology:
    Cellular Component: myosin complex [ISS]
    Biological Process: NONE FOUND
    Molecular Function: ATP binding [IEA]
    protein binding [IEA]
    ATPase activity, coupled [ISS]
    motor activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPPLSPANEA TAEIAASGEE NAGPVESDRL EKEKFLARVL AAMNGGPRSG NLASNNSSGS  60
   61 SLNSTLSGSA PLARPPKPPA SQARKQLRLL PKQREQSPVL SNGHTTRSTL SHQHTTNKYT 120
  121 LKSTGGNAGS STLSSSLLGN KDSEIPYEVS LKLPLNPPTG ADSDRHRLVN RSPSPALSVS 180
  181 SRCSTQSQSS ISNFTSNSRL QTPPRRVFPQ SYTRGSGGVD PYEMRQLESS PVVFDGNLSF 240
  241 VLGCQRQPVY QSMRASPSFE DPRTSSAYLS EKIQNFLKRT DHVQEEWTAM SRRTRRINSN 300
  301 SGRAGGSESR CTTPGSTCSG YDDYDTISLI ERQRERNSME RCGSVGRTRS SQNILTKAFQ 360
  361 LAKQLPHTPT SRGNSVARDR ESSVATISLT TGDNDDDDDR TIREEDDELS ELTVDLAEER 420
  421 STAHIATERL EAETAERLKL EKELGDQTNK VKNLQETTEK LEMELICAKS DLNGISEDED 480
  481 AENEDGVGGG VYKLKYERVA RELEFTKRRL HTQHEHDLEQ LVALKKHLEM KLSDAYEEVV 540
  541 EQRQVVGQWK RKAQKMTNEM NDLRMLLEEQ NARNNLLEKK QRKFDAECQS LQDAVRQERQ 600
  601 AKERYGREKD VLQAEKFTLE QTLADTRLDL EFKEEKLASL QRELEEMTFG GGTEEEFAQL 660
  661 RRSKNETERR AKEQEEELDE MAGQIQLLEQ AKLRLEMTLE TMRKEARRES QQRDEELEEV 720
  721 RGNGYKKIKA LECQLETEHE ERTLLLREKH ELERRLSSME DRDRVDRDAE EALNQKLRRD 780
  781 LRKYKALLKD AQTQLERLKA DTPGKTLIRQ LRNQLEDAES ARSLAMKARQ TAEAELTEVQ 840
  841 AMFDESHRAR NDAEERANAA HRDRAELQAQ IEENEEELGE LMKKYSATVK QLNTEQINVS 900
  901 EAEFKLNEME AERNNLKEQV AELQHRLDNV ENLGDPSMAM MSKRLELRTK ELESRLELEQ 960
  961 ATRARLEVQV NRHKEALEKL QNEVTQSKMR EMQAQDVIKK SQKSLRDMRE EFHAVSSREQ1020
 1021 ESLTRRKDLE KKVEQMESEG AALKNDLRLA LQRIADLQQA MEEEGEEELS ESDESLSSVG1080
 1081 SISDLEDRLR PVHVKRSSQQ SLNGSIGGGG GSVVSSTRTV VFEKDDNSPR NNAK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..360] PSI-BLAST 23.045757 Heavy meromyosin subfragment
    2 View Details [361..556] PSI-BLAST 4.69897 No description for 2dfsA was found.
    3 View Details [557..775] FFAS03 2.44 No description for 2i1jA was found.
    4 View Details [776..1065] PSI-BLAST 11.69897 Tropomyosin
    5 View Details [1066..1134] PSI-BLAST 3.69897 No description for 2iw5A was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle