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Protein Overview: Act88F-PA

General Information:
Name(s) found: Act88F-PA / FBpp0082597 [FlyBase]
Description(s) found:
Found 28 descriptions.
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  • The gene Actin 88F is referred to in FlyBase by the symbol Dmel\Act88F (CG5178, FBgn0000047). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:11265710..11267895. It has the cytological map location 88F5. Based on sequence similarity, it is predicted to have molecular function</span>: structural constituent of cytoskeleton. There is experimental evidence that it is involved in the biological process</span>: skeletal myofibril assembly; phagocytosis, engulfment. 82 alleles are reported. The phenotypes of these alleles are annotated with: dorsal medial muscle; tendon cell; sarcomere; myofibril; wing; indirect flight muscle. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 376 amino acids

    Gene Ontology:
    Cellular Component: actin filament [ISS]
    Biological Process: phagocytosis, engulfment [IMP]
    cytoskeleton organization [ISS]
    skeletal myofibril assembly [IMP]
    Molecular Function: ATP binding [IEA]
    protein binding [IEA]
    structural constituent of cytoskeleton [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCDDDAGALV IDNGSGMCKA GFAGDDAPRA VFPSIVGRPR HQGVMVGMGQ KDSYVGDEAQ  60
   61 SKRGILTLKY PIEHGIITNW DDMEKIWHHT FYNELRVAPE EHPVLLTEAP LNPKANREKM 120
  121 TQIMFETFNS PAMYVAIQAV LSLYASGRTT GIVLDSGDGV SHTVPIYEGF ALPHAILRLD 180
  181 LAGRDLTDYL MKILTERGYS FTTTAEREIV RDIKEKLCYV ALDFEQEMAT AAASTSLEKS 240
  241 YELPDGQVIT IGNERFRCPE ALFQPSFLGM ESCGIHETVY NSIMKCDVDI RKDLYANSVL 300
  301 SGGTTMYPGI ADRMQKEITA LAPSTIKIKI IAPPERKYSV WIGGSILASL STFQQMWISK 360
  361 QEYDESGPGI VHRKCF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..376] PSI-BLAST 154.0 Actin


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.76

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle