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Protein Overview: pic-PA

General Information:
Name(s) found: pic-PA / FBpp0082177 [FlyBase]
Description(s) found:
Found 22 descriptions.
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  • The gene piccolo is referred to in FlyBase by the symbol Dmel\pic (CG7769, FBgn0260962). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:8877978..8882454. It has the cytological map location 87D14-87D11. There is experimental evidence that it has the molecular function</span>: protein binding. Based on sequence similarity, it is predicted to be involved in the biological process</span>: protein ubiquitination during ubiquitin-dependent protein catabolic process; nucleotide-excision repair. 46 alleles are reported. The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: peripheral nervous system; adult segment; organ system; nervous system; external compound sense organ; adult mesothoracic segment; imaginal precursor; compound cell cluster organ; larval imaginal precursor; circulatory system. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1140 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEA]
    Biological Process: nucleotide-excision repair [ISS][NAS]
    protein ubiquitination during ubiquitin-dependent protein catabolic process [ISS]
    Molecular Function: protein binding [IPI]
    damaged DNA binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSHHYVVTAQ KPTAVVACLT GNFTSPTDLN LIIARNNQVE IDLVTPEGLR PLKEININGT  60
   61 IAVMRHFRPP DSNKDLLFIL TRRYNVMILE ARMVNDVITV VTKANGNVSD SVGIPSEGGV 120
  121 IAAIDPKARV IGMCLYQGLF TIIPMDKDAS ELKATNLRMD ELNVYDVEFL HGCLNPTVIV 180
  181 IHKDSDGRHV KSHEINLRDK EFMKIAWKQD NVETEATMLI PVPSPIGGVI VIGRESIVYH 240
  241 DGSNYHAVAP LTFRQSTINC YARVSSNGLR YLLGNMDGQL YMLFLGTAET SKGVTVKDIK 300
  301 VEQLGEISIP ECITYLDNGF LYIGARHGDS QLVRLNSEAI DGSYVVPVEN FTNLAPILDI 360
  361 AVVDLDRQGQ GQIITCSGSF KDGSLRIIRI GIGIQEHACI DLPGIKGMWS LKVGVDESPY 420
  421 ENTLVLAFVG HTRILTLSGE EVEETEIPGF ASDLQTFLCS NVDYDQLIQV TSDSVRLVSS 480
  481 ATKALVAEWR PTGDRTIGVV SCNTTQILVA SACDIFYIVI EDGSLREQSR RTLAYEVACL 540
  541 DITPLDETQK KSDLVAVGLW TDISAVILSL PDLETIYTEK LSGEIIPRSI LMTTFEGIHY 600
  601 LLCALGDGSM YYFIMDQTTG QLTDKKKVTL GTQPTTLRTF RSLSTTNVFA CSDRPTVIYS 660
  661 SNHKLVFSNV NLKEVNHMCS LNAQAYPDSL ALANKNAVIL GTIDEIQKLH IRTVPLGEGP 720
  721 RRIAYQESSQ TFAVSTLRID VHGRGGAKPL RNSASTQAQN ITCSSNFLPK PGGGNSTAAN 780
  781 AEVGQEIDVH NLLVIDQNTF EVLHAHQFVA PETISSLMSA KLGDDPNTYY VVATSLVIPE 840
  841 EPEPKVGRII IFHYHENKLT QVAETKVDGT CYALVEFNGK VLAGIGSFVR LYEWTNEKEL 900
  901 RMECNIQNMI AALFLKAKGD FILVGDLMRS ITLLQHKQME GIFVEIARDC EPKWMRAVEI 960
  961 LDDDTFLGSE TNGNLFVCQK DSAATTDEER QLLPELARFH LGDTVNVFRH GSLVMQNVGE1020
 1021 RTTPINGCVL YGTCNGAIGI VTQIPQDFYD FLHGLEERLK KIIKSVGKIE HTYYRNFQIN1080
 1081 SKVEPSEGFI DGDLIESFLD LSRDKMRDAV QGLELTLNGE RKSADVEDVI KIVEDLTRMH1140
 1141

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..1140] PSI-BLAST 1000.0 Crystal Structure of DDB1 In Complex with Simian Virus 5 V Protein


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.90

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle