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Protein Overview: Aos1-PA

General Information:
Name(s) found: Aos1-PA / FBpp0082065 [FlyBase]
Description(s) found:
Found 42 descriptions.
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  • The gene Aos1 is referred to in FlyBase by the symbol Dmel\Aos1 (CG12276, FBgn0029512). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:8258255..8259626. It has the cytological map location 87B10. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: positive regulation of NF-kappaB transcription factor activity. 6 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 337 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    SUMO activating enzyme complex [ISS]
    Biological Process: protein sumoylation [ISS]
    protein modification process [IEA]
    SMT3-dependent protein catabolic process [NAS]
    positive regulation of NF-kappaB transcription factor activity [IDA]
    Molecular Function: SUMO activating enzyme activity [ISS][NAS]
    protein binding [IPI]
    small protein activating enzyme activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVVDMDTSET AVELTEAENE LYDRQIRLWG LESQKRLRTA KILIAGLCGL GAEITKNIIL  60
   61 SGVNSVKLLD DKDVTEEDFC SQFLVPRESL NTNRAEASLT RARALNPMVD ISADREPLKE 120
  121 KTSEFFGQFD VVVVNGATNE ELLRIDTICR DLGVKFIATD VWGTFGFYFA SLQKHSYVED 180
  181 VIKHKVVANS EKKKKYETVS IPTQRDVDYP GYSAWLDFDV TEPSYLRKLK RNGPGVLLLS 240
  241 VLQKFRTTHK RDPSYKTREA DLELLRGIRD ELLPNSILGD EALGLIFAQI SPAVAVVGGV 300
  301 VAQEVIKVVT KLEAPHRNLF VFDPETCAGY VEAIGAK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..337] PSI-BLAST 75.221849 SUMO E1 ACTIVATING ENZYME SAE1-SAE2-MG-ATP COMPLEX


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.77

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle