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Protein Overview: CG14721-PA

General Information:
Name(s) found: CG14721-PA / FBpp0081906 [FlyBase]
Description(s) found:
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  • gi|28571654|ref|NP_650110.3| CG14721 [Drosophila melanogaster] [NCBI NR]
  • gi|28381251|gb|AAF54690.2| CG14721 [Drosophila melanogaster] [NCBI NR]
  • gi|19527811|gb|AAL90020.1| AT07857p [Drosophila melanogaster] [NCBI NR]
  • This gene is referred to in FlyBase by the symbol Dmel\CG14721 (CG14721, FBgn0037942). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:7561169..7562565. It has the cytological map location 86E17. Based on sequence similarity, it is predicted to have molecular function</span>: thiamin diphosphokinase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: thiamin metabolic process; thiamin diphosphate biosynthetic process. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG14721-PA translation from_gene[CG14721 CG14721 FBgn0037942] seq_release:3 mol_weight=38384 cds_boundaries:(3R:7,561,234..7,562,388[+]) aa_length:345 transcript_info:[CG14721-RA seq_release:3] gene_info:[gene symbol:CG14721 FBgn0037942 gene_boundarie [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q8T4A5) AT07857p (CG14721-PA) [DrosMelano7227.FASTAC.txt]
  • CG14721-PA [Drosophila melanogaster]gi|19527811|gb|AAL90020.1| AT07857p [Drosophila melanogaster]gi|28571654|ref|NP_650110.3| CG14721-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3R:join(7561216..7561579,7561641..7562165,7562225..7562373); ID=FBpp0081906; name=CG14721-PA; parent=FBgn0037942,FBtr0082430; dbxref=FlyBase:FBpp0081906,FlyBase_Annotation_IDs:CG14721-PA,GB_protein:AAF54690.2,REFSEQ:NP_650110,GB_protein: [fly-100309-contam.fasta]
  • CG14721-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • AT07857p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3R:join(7561216..7561579,7561641..7562165,7562225..7562373); ID=FBpp0081906; name=CG14721-PA; parent=FBgn0037942,FBtr0082430; dbxref=FlyBase:FBpp0081906,FlyBase_Annotation_IDs:CG14721-PA,GB_protein:AAF54690.2,REFSEQ:NP_650110,GB_protein:AAF54690; MD5=9a841e1e79578582bff268f3dbe5afe1; length=345; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3R:join(7561216..7561579,7561641..7562165,7562225..7562373); ID=FBpp0081906; name=CG14721-PA; parent=FBgn0037942,FBtr0082430; dbxref=FlyBase:FBpp0081906,FlyBase_Annotation_IDs:CG14721-PA,GB_protein:AAF54690.2,REFSEQ:NP_650110,GB_protein:AAF54690; MD5=9a841e1e79578582bff268f3dbe5afe1; length=345; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • AT07857p OS=Drosophila melanogaster GN=CG14721 PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=3R:join(7561216..7561579,7561641..7562165,7562225..7562373); ID=FBpp0081906; name=CG14721-PA; parent=FBgn0037942,FBtr0082430; dbxref=FlyBase:FBpp0081906,FlyBase_Annotation_IDs:CG14721-PA,GB_protein:AAF54690.2,REFSEQ:NP_650110,GB_protein:AAF54690,FlyMine:FBpp0081906,modMine:FBpp0081906; MD5=9a841e1e79578582bff268f3dbe5afe1; length=345; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3R:join(11735494..11735857,11735919..11736443,11736503..11736651); ID=FBpp0081906; name=CG14721-PA; parent=FBgn0037942,FBtr0082430; dbxref=FlyBase:FBpp0081906,FlyBase_Annotation_IDs:CG14721-PA,GB_protein:AAF54690.2,REFSEQ:NP_650110,GB_protein:AAF54690,FlyMine:FBpp0081906,modMine:FBpp0081906; MD5=9a841e1e79578582bff268f3dbe5afe1; length=345; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3R:join(11735494..11735857,11735919..11736443,11736503..11736651); ID=FBpp0081906; name=CG14721-PA; parent=FBgn0037942,FBtr0082430; dbxref=FlyBase:FBpp0081906,FlyBase_Annotation_IDs:CG14721-PA,GB_protein:AAF54690.2,REFSEQ:NP_650110,GB_protein:AAF54690,FlyMine:FBpp0081906,modMine:FBpp0081906; MD5=9a841e1e79578582bff268f3dbe5afe1; length=345; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • AT07857p OS=Drosophila melanogaster GN=CG14721 PE=1 SV=1 [DROME.fasta.20160308]
  • FBpp0081906 type=protein; loc=3R:join(11735494..11735857,11735919..11736443,11736503..11736651); ID=FBpp0081906; name=CG14721-PA; parent=FBgn0037942,FBtr0082430; dbxref=FlyBase:FBpp0081906,FlyBase_Annotation_IDs:CG14721-PA,GB_protein:AAF54690.2,REFSEQ:NP_650110,GB_protein:AAF54690,FlyMine:FBpp0081906,modMine:FBpp0081906; MD5=9a841e1e79578582bff268f3dbe5afe1; length=345; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=3R:join(11735494..11735857,11735919..11736443,11736503..11736651); ID=FBpp0081906; name=CG14721-PA; parent=FBgn0037942,FBtr0082430; dbxref=FlyBase:FBpp0081906,FlyBase_Annotation_IDs:CG14721-PA,GB_protein:AAF54690.2,REFSEQ:NP_650110,GB_protein:AAF54690,UniProt/TrEMBL:Q8T4A5,FlyMine:FBpp0081906,modMine:FBpp0081906; MD5=9a841e1e79578582bff268f3dbe5afe1; length=345; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 345 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: thiamin metabolic process [IEA]
    thiamin diphosphate biosynthetic process [IEA]
    Molecular Function: thiamin diphosphokinase activity [ISS]
    ATP binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MILVKLYGTG GCTMTAAGAP GSALNWMRRS RHGFGLIRIT RVGRPAHQRT THSATHRFLC  60
   61 TKTTIGFRQQ MDHTIPPKEY KWTPGNLINE NFKLGDHGHV CVVLNRQIQV PAHVVKLLWK 120
  121 NAAVRCAVDG GSNHWRDFVV AQAMSKKANG SAPTTPLEPL DVITGDFDSI TEETVDFFKT 180
  181 TPKVHTPDQD ATDFTKAMAV LQPVMTQRKI QDVVVFHDTS GRLDQVMANL NTLYKSQKDN 240
  241 CNVFLLSGDS VTWLLRPGKH TIQVPVDLVT SQRWCSLMPV GSSAHNVTTT GLKWNLYHAQ 300
  301 LEFGGMVSTS NTYATEFVQV ETDANLIWSM GAYEFEDKVR QAAKT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..345] PSI-BLAST 73.39794 Thiamin pyrophosphokinase, substrate-binding domain; Thiamin pyrophosphokinase, catalytic domain


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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