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Protein Overview: CG14721-PA

General Information:
Name(s) found: CG14721-PA / FBpp0081906 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG14721 (CG14721, FBgn0037942). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:7561169..7562565. It has the cytological map location 86E17. Based on sequence similarity, it is predicted to have molecular function</span>: thiamin diphosphokinase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: thiamin metabolic process; thiamin diphosphate biosynthetic process. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 345 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: thiamin metabolic process [IEA]
    thiamin diphosphate biosynthetic process [IEA]
    Molecular Function: thiamin diphosphokinase activity [ISS]
    ATP binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MILVKLYGTG GCTMTAAGAP GSALNWMRRS RHGFGLIRIT RVGRPAHQRT THSATHRFLC  60
   61 TKTTIGFRQQ MDHTIPPKEY KWTPGNLINE NFKLGDHGHV CVVLNRQIQV PAHVVKLLWK 120
  121 NAAVRCAVDG GSNHWRDFVV AQAMSKKANG SAPTTPLEPL DVITGDFDSI TEETVDFFKT 180
  181 TPKVHTPDQD ATDFTKAMAV LQPVMTQRKI QDVVVFHDTS GRLDQVMANL NTLYKSQKDN 240
  241 CNVFLLSGDS VTWLLRPGKH TIQVPVDLVT SQRWCSLMPV GSSAHNVTTT GLKWNLYHAQ 300
  301 LEFGGMVSTS NTYATEFVQV ETDANLIWSM GAYEFEDKVR QAAKT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..345] PSI-BLAST 73.39794 Thiamin pyrophosphokinase, substrate-binding domain; Thiamin pyrophosphokinase, catalytic domain


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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