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Protein Overview: CG6744-PA, FBpp0...

General Information:
Name(s) found: FBpp0300531 [FlyBase]
CG6744-PA / FBpp0081878 [FlyBase]
Description(s) found:
Found 27 descriptions.
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  • type=protein; loc=3R:complement(7259278..7259686,7259894..7261021,7261084..7261298); ID=FBpp0300531; name=CG6744-PB; parent=FBgn0037901,FBtr0308211; dbxref=FlyBase:FBpp0300531,FlyBase_Annotation_IDs:CG6744-PB,REFSEQ:NP_001247048,GB_protein:AFH06366; MD5=7e9a82f6d1bb6f42b7caf6d80f218149; length=583; release=r5.56; species=Dmel; [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\CG6744 (CG6744, FBgn0037901). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:7259210..7261425. It has the cytological map location 86E5. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: 3'-5' exonuclease activity; nucleic acid binding. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: nucleobase, nucleoside, nucleotide and nucleic acid metabolic process. 6 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 583 amino acids

    Gene Ontology:
    Cellular Component: intracellular [IEA]
    Biological Process: nucleobase, nucleoside, nucleotide and nucleic acid metabolic process [IEA]
    Molecular Function: nucleic acid binding [IEA]
    3'-5' exonuclease activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTRESAVATK RNWAILAAGV GLVYVLVRHR HRLLCPLRRV WSFGSLVPQR RIEVINSVQD  60
   61 PTTQWVLNEL KNHCQTFKVL GFDCEWITVG GSRRPVALLQ LSSHRGLCAL FRLCHMKQIP 120
  121 QDLRELLEDD SVIKVGVAPQ EDAMKLSHDY GVGVASTLDL RFLCVMAGHK PEGLGKLSKT 180
  181 HLNYTLDKHW RLACSNWEAK TLEPKQLDYA ANDALMAVAI YQKLCRDLQP KHFWQRRQLD 240
  241 DNSMHNKFEP FLDVDFTKGF TLNPSGSGVT RSKGSTQSKS NKWVPKKQPY RQIATRTKDF 300
  301 YDNCLLQAPD GELLCTIDRR KASWYLNQNL GTHISEEPFT VRLNFEPAGR AVGDVGRFYQ 360
  361 TIKKNQCVVC GDRDAYIRKN VVPREYRKHF PLVMKSHTSD DVLLLCPTCH QLSNISDLRV 420
  421 RSKLAVQCEA PFKQEDGSVK YHDDPQLKRV QSAGKALLHH GAKIPAAKKA EMEKTLLDYY 480
  481 SDQTDITEDL LRQAASVEYR VENSDYCQHG ERVVQQYRDH FGGLVELERL WRQHFLHTMQ 540
  541 PRFLPELWNV NHNADRLEVR ASEGRIDKAD LMVAGLDAKI KET

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..583] PSI-BLAST 111.0 STRUCTURE OF LARGE FRAGMENT OF ESCHERICHIA COLI DNA POLYMERASE I COMPLEXED WITH D/TMP

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • nuclease activity
    		•  0.687593316275503 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  0.419443418216132 bayes_pls_golite062009
  • hydrolase activity
    		•  0.402789197743512 bayes_pls_golite062009
  • catalytic activity
    		•  0.351839891620214 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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