YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: CG5214-PA

General Information:
Name(s) found: CG5214-PA / FBpp0081834 [FlyBase]
Description(s) found:
Found 23 descriptions.
SHOW ALL
  • This gene is referred to in FlyBase by the symbol Dmel\CG5214 (CG5214, FBgn0037891). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:7070006..7072586. It has the cytological map location 86D9. Based on sequence similarity, it is predicted to have molecular function</span>: dihydrolipoyllysine-residue succinyltransferase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: tricarboxylic acid cycle. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 468 amino acids

    Gene Ontology:
    Cellular Component: lipid particle [IDA]
    mitochondrial oxoglutarate dehydrogenase complex [ISS]
    Biological Process: tricarboxylic acid cycle [ISS]
    Molecular Function: dihydrolipoyllysine-residue succinyltransferase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTGIISIVTR RLPQTLGMRA LRSNEVKRCI RQYSRLVACA AQQQQLLRQD GSNRCQEATR  60
   61 LLTWQGIHTT SSLWSEQTVN VPPFADSIAE GDIKFTCKVG DSFAADEAVM EIETDKTTVA 120
  121 VPAPFSGTLT DILVKDGDTV KPGQALFKIK PGAAPAKAAA PAAAPAPAAP KAAPAPAAAP 180
  181 KPAPPPPAAG APKPPPPPPP KAAPRPPPPA PVAALKPAVA QVKVPPADGS RQILGTRSEQ 240
  241 RVKMNRMRLK IAARLKDAQN TCAMLTTFNE VDMSYAMDFR KQNLDAFTKK YGIKFGFMSI 300
  301 FAKASAYALQ DQPVVNAVID GTDIVYRDYV DISVAVATPR GLVVPVIRNV EGMNYADIEI 360
  361 ALAGLADKAR RDAITVEDMD GGTFTISNGG VFGSLMGTPI INPPQSAILG MHGIFERPIA 420
  421 VKGEVKIRPM MYIALTYDHR IIDGREAVLF LRKIKAAVEN PAIIVAGL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..73] PSI-BLAST 13.30103 No description for 2qf7A was found.
    2 View Details [74..235] PSI-BLAST 19.09691 The crystal structure of dihydrolipoamide dehydrogenase and dihydrolipoamide dehydrogenase-binding protein (didomain) subcomplex of human pyruvate dehydrogenase complex.
    3 View Details [236..468] PSI-BLAST 89.522879 Dihydrolipoamide succinyltransferase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • catalytic activity
    		•  0.985567717478902 bayes_pls_golite062009
  • transferase activity
    		•  0.65532722795675 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  0.590907147191141 bayes_pls_golite062009
  • transferase activity, transferring acyl groups other than amino-acyl groups
    		•  0.589573845516701 bayes_pls_golite062009
  • acyltransferase activity
    		•  0.58932324215015 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle